Sex differences in the analgesic effects of ICI 182,780 and Flutamide on ureteral calculosis in rats

Hormones and Behavior

Volumn 59, Issue 1, 2011, Pages 9-13

  Affaitati, Giannapia ^a   Ceccarelli, Ilaria ^b   Fiorenzani, Paolo ^b   Rossi, Cosmo ^a   Pace, Maria Caterina ^c   Passavanti, Maria Beatrice ^c   Aurilio, Caterina ^c   Sorda, Giuseppina ^d   Danielli, Barbara ^d   Giamberardino, Maria Adele ^a   Aloisi, Anna Maria ^b  

^a UNIVERSITY OF CHIETI   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

^c SECOND UNIVERSITY OF NAPLES   (Italy)

^d Ospedale 21   (Italy)

Author keywords

Receptor antagonists; Sex hormones; Visceral pain

Indexed keywords

ALMOND OIL; ESTRADIOL; FLUTAMIDE; FULVESTRANT; TESTOSTERONE;

ANALGESIC ACTIVITY; ANALYSIS OF VARIANCE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; ESTRADIOL BLOOD LEVEL; FEMALE; HORMONE BLOOD LEVEL; MALE; NONHUMAN; PAIN ASSESSMENT; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; SHAM PROCEDURE; SURGICAL TECHNIQUE; TESTOSTERONE BLOOD LEVEL; TREATMENT OUTCOME; TREATMENT RESPONSE; URETER STONE; VISCERAL PAIN;

ANALGESICS; ANALYSIS OF VARIANCE; ANIMALS; ESTRADIOL; FEMALE; FLUTAMIDE; MALE; PAIN; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; SEX CHARACTERISTICS; TESTOSTERONE; URETERAL CALCULI;

EID: 78651427511     PISSN: 0018506X     EISSN: 10956867     Source Type: Journal    
DOI: 10.1016/j.yhbeh.2010.09.008     Document Type: Article

References (33)

1. Aloisi A.M., Bonifazi M. Sex hormones, central nervous system and pain. Horm. Behav. 2006, 50:1-7.
2. Aloisi A.M., Ceccarelli I. Role of gonadal hormones in formalin-induced pain responses of male rats: modulation by estradiol and naloxone administration. Neuroscience 2000, 95:559-566.
3. Aloisi A.M., Affaitati G., Ceccarelli I., Fiorenzani P., Lerza R., Rossi C., Pace M.C., Chiefari M., Aurilio C., Giamberardino M.A. Estradiol and testosterone differently affect visceral pain-related behavioural responses in male and female rats. Eur. J. Pain 2010, 14:602-607.
4. Bradshaw H.B., Berkley K.J. Estrogen replacement reverses ovariectomy-induced vaginal hyperalgesia in the rat. Maturitas 2002, 41:157-165.
5. Canonaco M., Giusi G., Madeo A., Facciolo R.M., Lappano R., Canonaco A., Maggiolini M.J. A sexually dimorphic distribution pattern of the novel estrogen receptor G-protein-coupled receptor 30 in some brain areas of the hamster. Endocrinol. 2008, 196:131-138.
6. Chaban V.V., Micevych P.E. Estrogen receptor-alpha mediates estradiol attenuation of ATP-induced Ca2+ signaling in mouse dorsal root ganglion neurons. J. Neurosci. Res. 2005, 81:31-37.
7. Chaban V.V., Mayer E.A., Ennes H.S., Micevych P.E. Estradiol inhibits ATP-induced intracellular calcium concentration increase in dorsal root ganglia neurons. Neuroscience 2003, 118:941-948.
8. Clairborne J., Nag S., Mokha S.S. Activation of opioid receptor like-1 receptor in the spinal cord produces sex-specific antinociception in the rat: estrogen attenuates antinociception in the female, whereas testosterone is required for the expression of antinociception in the male. J. Neurosci. 2006, 26:13048-13053.
9. Craft R.M. Modulation of pain by estrogens. Pain 2007, 132:S3-S12.
10. Craft R.M., Mogil J.S., Aloisi A.M. Sex differences in pain and analgesia: the role of gonadal hormones. Eur. J. Pain 2004, 8:397-411.
11. Fehrenbacher J.C., Loverme J., Clarke W., Hargreaves K.M., Piomelli D., Taylor B.K. Rapid pain modulation with nuclear receptor ligands. Brain Res. Rev. 2009, 60:114-124.
12. Fernández-Fernández R., Tena-Sempere M., Roa J., Castellano J.M., Navarro V.M., Aguilar E., Pinella L. Direct stimulatory effect of ghrelin on pituitary release of LH through a nitric oxide-dependent mechanism that is modulated by estrogen. Reproduction 2007, 133:1223-1232.
13. Gaumond I., Arsenault P., Marchand S. The role of sex hormones on formalin-induced nociceptive responses. Brain Res. 2002, 958:139-145.
14. Giamberardino M.A., Valente R., De Bigontina P., Vecchiet L. Artificial ureteral calculosis in rats: behavioural characterization of visceral pain episodes and their relationship with referred lumbar muscle hyperalgesia. Pain 1995, 61:459-469.
15. Giamberardino M.A., Berkley K.J., Affaitati G., Lerza R., Centurione L., Lapenna D., Vecchiet L. Influence of endometriosis on pain behaviors and muscle hyperalgesia induced by a ureteral calculosis in female rats. Pain 2002, 95:247-257.
16. Giamberardino M.A., Tafuri E., Savini A., Fabrizio A., Affaitati G., Lerza R., Di Ianni L., Lapenna D., Mezzetti A. Contribution of myofascial trigger points to migraine symptoms. J. Pain 2007, 8:869-878.
17. Hildebrand F., Hubbard W.J., Choudhry M.A., Thobe B.M., Pape H.C., Chaudry I.H. Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females. J. Leukoc. Biol. 2006, 80:759-765.
18. Howell A., Osborne C.K., Morris C., Wakeling A.E. ICI 182, 780 (Faslodex): development of a novel, "pure" antiestrogen. Cancer 2000, 89:817-825.
19. Huynh H., Alpert L., Alaoui-Jamali M.A., Ng C.Y., Chan T.W. Co-administration of finasteride and the pure anti-oestrogen ICI 182, 780 act synergistically in modulating the IGF system in rat prostate. J. Endocrinol. 2001, 171:109-118.
20. Kang I.H., Kim H.S., Shin J.H., Kim T.S., Moon H.J., Kim I.Y., Choi K.S., Kil K.S., Park Y.I., Dong M.S., Han S.Y. Comparison of anti-androgenic activity of flutamide, vinclozolin, procymidone, linuron, and p, p?-DDE in rodent 10-day Hershberger assay. Toxicology 2004, 199:145-159.
21. Kuba T., Wu H.B., Nazarian A., Festa E.D., Barr G.A., Jenab S., Inturrisi C.E., Quinones-Jenab V. Estradiol and progesterone differentially regulate formalin-induced nociception in ovariectomized female rats. Horm. Behav. 2006, 49:441-449.
22. Kuhn J., Dina O.A., Goswami C., Suckow V., Levine J.D., Hucho T. GPR30 estrogen receptor agonists induce mechanical hyperalgesia in the rat. Eur. J. Neurosci. 2008, 27:1700-1709.
23. Labus J.S., Naliboff B.N., Fallon J., Berman S.M., Suyenobu B., Bueller J.A., Mandelkern M., Mayer E.A. Sex differences in brain activity during aversive visceral stimulation and its expectation in patients with chronic abdominal pain: a network analysis. NeuroImage 2008, 41:1032-1043.
24. Levin E.R. Plasma membrane estrogen receptors. Trends Endocrinol. Metab. 2009, 20:477-482.
25. Lu C.L., Hsieh J.C., Dun N.J., Oprea T.I., Wang P.S., Luo J.C., Lin H.C., Chang F.Y., Lee S.D. Estrogen rapidly modulates 5-hydroxytrytophan-induced visceral hypersensitivity via GPR30 in rats. Gastroenterology 2009, 137:1040-1050.
26. Maggiolini M., Picard D. The unfolding stories of GPR30, a new membrane-bound estrogen receptor. J. Endocrinol. 2010, 204:105-114.
27. Micevych P.E., Mermelstein P.G. Membrane estrogen receptors acting through metabotropic glutamate receptors: an emerging mechanism of estrogen action in brain. Mol. Neurobiol. 2008, 38:66-77.
28. Shimizu T., Yu H.P., Hsieh Y.C., Choudhry M.A., Suzuki T., Bland K.I., Chaudry I.H. Flutamide attenuates pro-inflammatory cytokine production and hepatic injury following trauma-hemorrhage via estrogen receptor-related pathway. Ann. Surg. 2007, 245:297-304.
29. Simard J., Luthy I., Guay J., Bélanger A., Labrie F. Characteristics of interaction of the antiandrogen flutamide with the androgen receptor in various target tissues. Mol. Cell. Endocrinol. 1986, 44:261-270.
30. Tetel M.J. Modulation of steroid action in the central and peripheral nervous systems by nuclear receptor coactivators. Psychoneuroendocrinology 2009, 34:S9-S19.
31. Tetel M.J., Auger A.P., Charlier T.D. Who's in charge? Nuclear receptor coactivator and corepressor function in brain and behavior. Front Neuroendocrinol. 2009, 30:328-342.
32. Viguier-Martinez M.C., Hochereau de Reviers M.T., Barenton B., Perreau C. Effect of a non-steroidal antiandrogen, flutamide, on the hypothalamo-pituitary axis, genital tract and testis in growing male rats: endocrinological and histological data. Acta Endocrinol. (Copenh) 1983, 102:299-306.
33. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983, 16:109-110.