Enzyme prodrug therapy designed to target l-methioninase to the tumor vasculature

Cancer Letters

Volumn 301, Issue 2, 2011, Pages 177-184

  Van Rite, Brent D ^a   Lazrak, Yahya A ^a   Pagnon, Magali L ^a   Palwai, Naveen R ^a   Neves, Luís F F ^a   McFetridge, Peter S ^a   Harrison, Roger G ^a  

^a University of Oklahoma   (United States)

Author keywords

Breast cancer; Enzyme; L methioninase annexin V; Prodrug; Tumor vasculature

Indexed keywords

HYBRID PROTEIN; LIPOCORTIN 5; METHIONINE GAMMA LYASE; SELENOMETHIONINE;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME PRODRUG THERAPY; HUMAN; HUMAN CELL; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TUMOR VASCULARIZATION; VASCULAR ENDOTHELIUM;

ANNEXIN A5; BREAST NEOPLASMS; CARBON-SULFUR LYASES; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOTHELIAL CELLS; FEMALE; HUMANS; KINETICS; METHANOL; NEOVASCULARIZATION, PATHOLOGIC; ORGANOSELENIUM COMPOUNDS; PRODRUGS; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; SELENOMETHIONINE;

EID: 78651417648     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2010.11.013     Document Type: Article

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