Melanoma: Is hair the root of the problem?

Pigment Cell and Melanoma Research

Volumn 24, Issue 1, 2011, Pages 110-118

  Gomez Garcia, Angela M ^a,b   McLaren, Christine E ^a   Meyskens, Frank L ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Hair follicle; Melanoma; Stem cell niche; Ultraviolet light

Indexed keywords

ARTICLE; CANCER INCIDENCE; ESTHETIC SURGERY; HAIR; HUMAN; MELANOMA; SUN EXPOSURE;

EID: 78651416212     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2010.00782.x     Document Type: Article

References (32)

1. Autier, P., and Dore, J.F. (1998). Influence of sun exposures during childhood and during adulthood on melanoma risk. EPIMEL and EORTC Melanoma Cooperative Group. European Organisation for Research and Treatment of Cancer. Int. J. Cancer 77, 533-537.
2. Blume, U., Ferracin, J., Verschoore, M., Czernielewski, J.M., and Schaefer, H. (1991). Physiology of the vellus hair follicle: hair growth and sebum excretion. Br. J. Dermatol. 124, 21-28.
3. Blume-Peytavi, U. (2008). Hair Growth and Disorders. (Berlin: Springer).
4. Bulliard, J.L., De Weck, D., Fisch, T., Bordoni, A., and Levi, F. (2007). Detailed site distribution of melanoma and sunlight exposure: aetiological patterns from a Swiss series. Ann. Oncol. 18, 789-794.
5. Elwood, J.M., and Gallagher, R.P. (1998). Body site distribution of cutaneous malignant melanoma in relationship to patterns of sun exposure. Int. J. Cancer 78, 276-280.
6. Franbourg, A., Hallegot, P., Baltenneck, F., Toutain, C., and Leroy, F. (2003). Current research on ethnic hair. J. Am. Acad. Dermatol. 48, S115-119.
7. Fujimoto, A., Kimura, R., Ohashi, J. et al. (2008). A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness. Hum. Mol. Genet. 17, 835-843.
8. Green, A.C., Kimlin, M., Siskind, V., and Whiteman, D.C. (2006). Hypothesis: hair cover can protect against invasive melanoma on the head and neck (Australia). Cancer Causes Control 17, 1263-1266.
9. Grojean, R.E., Sousa, J.A., and Henry, M.C. (1980). Utilization of solar radiation by polar animals: an optical model for pelts. Appl. Opt. 19, 339-346.
10. Iyengar, B. (1998). The hair follicle: a specialised UV receptor in the human skin? Biol. Signals Recept. 7, 188-194.
11. Koon, D. (1998). Is Polar Bear Hair Fiber Optic? Appl. Opt. 37, 3198-3200.
12. Kwon, H., Liu, P.H., Lew, D.-H., Nishimura, E.K., and Orgill, D.P. (2008). Hair Follicle Melanocyte Cells as a Renewable Source of Melanocytes for Culture and Transplantation. In EPlasty, Open Science Co LLC, Springfield.
13. Langbein, L., Yoshida, H., Praetzel-Wunder, S., Parry, D.A., and Schweizer, J. (2010). The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle. J. Invest. Dermatol. 130, 55-73.
14. Mangelsdorf, S., Otberg, N., Maibach, H.I., Sinkgraven, R., Sterry, W., and Lademann, J. (2006). Ethnic variation in vellus hair follicle size and distribution. Skin Pharmacol. Physiol. 19, 159-167.
15. McCreary, D.R., Hildebrandt, T.B., Heinberg, L.J., Boroughs, M., and Thompson, J.K. (2007). A Review of Body Image Influences on Men's Fitness Goals and Supplement Use. Am. J. Mens Health 1, 307-316.
16. Meyer, K.C., Klatte, J.E., Dinh, H.V., Harries, M.J., Reithmayer, K., Meyer, W., Sinclair, R., and Paus, R. (2008). Evidence that the bulge region is a site of relative immune privilege in human hair follicles. Br. J. Dermatol. 159, 1077-1085.
17. Meyskens, F.L., Young, A.R., and Berwick, M.. (2006). Cutaneous Malignant Melanoma: What is the Role of Ultraviolet Radiation. In American Society of Clinical Oncology: Educational Track 2006. American Society of Clinical Oncology, Alexandria.
18. Nishimura, E.K., Jordan, S.A., Oshima, H., Yoshida, H., Osawa, M., Moriyama, M., Jackson, I.J., Barrandon, Y., Miyachi, Y., and Nishikawa, S. (2002). Dominant role of the niche in melanocyte stem-cell fate determination. Nature 416, 854-860.
19. Oliveria, S.A., Saraiya, M., Geller, A.C., Heneghan, M.K., and Jorgensen, C. (2006). Sun exposure and risk of melanoma. Arch. Dis. Child. 91, 131-138.
20. Otberg, N., Richter, H., Schaefer, H., Blume-Peytavi, U., Sterry, W., and Lademann, J. (2004). Variations of hair follicle size and distribution in different body sites. J. Invest. Dermatol. 122, 14-19.
21. Parra, E.J. (2007). Human pigmentation variation: evolution, genetic basis, and implications for public health. Am. J. Phys. Anthropol. Suppl. 45, 85-105.
22. Randall, V.A. (2008). Androgens and hair growth. Dermatol. Ther. 21, 314-328.
23. Sacco, J.J., Botten, J., Macbeth, F., Bagust, A., and Clark, P. (2010). The average body surface area of adult cancer patients in the UK: a multicentre retrospective study. PLoS ONE 5, e8933.
24. Schneider, M.R., Schmidt-Ullrich, R., and Paus, R. (2009). The hair follicle as a dynamic miniorgan. Curr. Biol. 19, R132-142.
25. Siervogel, R.M., Roche, A.F., Himes, J.H., Chumlea, W.C., and McCammon, R. (1982). Subcutaneous fat distribution in males and females from 1 to 39 years of age. Am. J. Clin. Nutr. 36, 162-171.
26. Slominski, A., Wortsman, J., Plonka, P.M., Schallreuter, K.U., Paus, R., and Tobin, D.J. (2005). Hair follicle pigmentation. J. Invest. Dermatol. 124, 13-21.
27. Sun, F., Chaney, A., Anderson, R., and Aguilar, G. (2009). Thermal modeling and experimental validation of human hair and skin heated by broadband light. Lasers Surg. Med. 41, 161-169.
28. von Thaler, A.K., Kamenisch, Y., and Berneburg, M. (2010). The role of ultraviolet radiation in melanomagenesis. Exp. Dermatol. 19, 81-88.
29. Vogt, A., Hadam, S., Heiderhoff, M., Audring, H., Lademann, J., Sterry, W., and Blume-Peytavi, U. (2007). Morphometry of human terminal and vellus hair follicles. Exp. Dermatol. 16, 946-950.
30. Williams, M.L., and Pennella, R. (1994). Melanoma, melanocytic nevi, and other melanoma risk factors in children. J. Pediatr. 124, 833-845.
31. Yu, H., Fang, D., Kumar, S.M., Li, L., Nguyen, T.K., Acs, G., Herlyn, M., and Xu, X. (2006). Isolation of a novel population of multipotent adult stem cells from human hair follicles. Am. J. Pathol. 168, 1879-1888.
32. Zanetti, R., Franceschi, S., Rosso, S., Colonna, S., and Bidoli, E. (1992). Cutaneous melanoma and sunburns in childhood in a southern European population. Eur. J. Cancer 28A, 1172-1176.