A study of the hepatic tolerance of the ethyl acetate fraction of Morinda morindoides (Baker) Milne-Redhead (Rubiaceae) extract in rabbit

Tropical Journal of Pharmaceutical Research

Volumn 9, Issue 6, 2010, Pages 573-579

  Tra Bi, I Otis ^a   Djyh, B Nazaire ^a   Bahi, C ^a   Meite, S ^a   N'guessan, J David ^a  

^a UNIVERSITÉ FÉLIX HOUPHOUËT BOIGNY   (Côte d’Ivoire)

Author keywords

Hepatic tolerance; Morinda morindoides; Serum biochemical parameters

Indexed keywords

ACETIC ACID; ACETIC ACID ETHYL ESTER; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LACTATE DEHYDROGENASE; MORINDA MORINDOIDES EXTRACT; PLANT EXTRACT; PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD SAMPLING; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG DOSE COMPARISON; EXPERIMENTAL RABBIT; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GLUCOSE BLOOD LEVEL; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER METABOLISM; MALE; MEDICINAL PLANT; MORINDA MORINDOIDES; NONHUMAN; NORMAL VALUE; PROTEIN BLOOD LEVEL; SOLVENT EXTRACTION; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 78651414308     PISSN: 15965996     EISSN: 15969827     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Tona L, Ngimbi NP, Tsakala M, Messia K, Cimanga RK, Apers S, De Brune T, Totte J, Pieters L, Vlietinck AJ. Biological screening of traditional preparations from some medicinal plants used as antidiarrheal in Kinshasa, Congo. Phytomedicine, 1999; 6 (1): 59-66.
2. Zirihi GN, Mambu L, Guede-Guina F, Bodo B, Grellier P. In vitro antiplasmodial activity and cytotoxity of 33 west African plants used for treatment of malaria. J Ethnopharmacol, 2005; 98: 281-285.
3. Moroh, JL, Bahi C, Dje K, Loukou YG, Guede-Guina, F. Etude de l'activité antimicrobienne de l'extrait acétatique (EAC) de Morinda morindoides (Baker) Milne-Readhead (Rubiaceae) sur la croissance in vitro des souches d'Escherichia coli. Bulletin de la Société Royale des Sciences de Liège, 2008; 77: 44-61.
4. Meite S, N'Guessan JD, Bahi C, Yapi HF, Djaman AJ and Guede-Guina F: Antidiarrheoal activity of the ethyl acetate extract of Morinda morindoides in rats. Trop J Pharm Res, 2009; 8 (3): 201-207
5. Kamo IL. BE: Etude des effets de BGG F1 sur le Coeur isolé de rat et la pression artérielle de lapin. DEA Biotechnologie, Université Abidjan- Cocody, 2008; p 34
6. Cimanga K, Kambu K, Tona L, Hermans N, Apers S, Totte J, Pieters L, Vlietink AJ. Cytotoxicity and in vitro susceptibility of Entamoeba hitolytica to Morinda morindoides leaf extracts and its isolated constituents. J Ethnopharmacol, 2006; 107: 83-90
7. Bagre, I, Bahi C, Gnahoue, G, Djaman, AJ, Guede, GF. Composition phytochimique et évaluation in-vitro de l'activité antifongique des extraits des feuilles de Morinda morindoïdes (baker) Milne-Redhead (Rubiaceae) sur Aspergillus fumigatus et candida albicans. J. Sci.Pharm. Biol., 2007; 8(1): 15-23.
8. Cimanga KR, Mukenyi PNK, Kambu KO, Tona LG, Apers S, Totte J, Pieters L, Vlietinck AJ. The spasmolytic activity of extracts and some isolated compounds from the leaves of Morinda morindoides (Baker) Milne-Redh. (Rubiaceae). J Ethnopharmacol, 2010; 127: 215-220.
9. Cimanga K, De Bryune T, Aleidis L, Pieters L, Clays M, Vanden BD, Kambu, K, Tona, L, Vlietinck, A. Flavonoid-O-glycosides from the leaves of Morinda morindoides. Phytochemistry, 1995; 5: 1301-1303.
10. Cimanga K, De Bryune T, Van Poel B, Ma Y, Claeys M, Pieters L, Kambu K, Tona L, Bakana P, Vanden BD Vlietinck A.Complementmodulating properties of a kaempferol 7-Orhamnosylophoroside from the leaves of Morinda morindoides. Planta medica, 1997; 63: 220-223
11. Cimanga KR, Tona LG, Kambu KO, Messia KG, Muyembe TJJ, Apers S, Pieters L, Vlietinck AJ. Antimalarial activity of some extracts and isolated constituents from Morinda morindoides. J Nat Remedies, 2008; 8(2): 191-202.
12. Hodgson E. A Text Book of Modern Toxicology, 3rd edn, John Wiley and Sons, Inc, New Jersey, 2004; pp 203-211
13. Guédé-Guina F, Vangah-Manda M, Harouna D, Bahi C. Potencies of Misca, a plant source concentrate against fungi. J. Ethno pharmacol. 1993; 14 (2): 45-53
14. Council Directive 86/609/EEC of 24 November 1986 on the approximation of laws, Regulations and administrative provisions of the member states regarding the protection of animals used for experimental and other scientific purposes Official Journal L 358, 18/12/1986; pp 0001-0028
15. Schmidt E, Schmidt FW. Manuel d'enzymologie Clinique. Serie Boehringer Mannheim Diagnostica, 1973; p 76
16. Medirabbit.com. Valeurs de référence de biochimie sanguine, 2004 http://www.medirabbit.com/FR/Hematologie/biochimie/bloodchemistryfr.htm
17. Founzegue AC, Adama C, N'Guessan JD, Koffi GK, Djaman AJ, Guede-Guina F Etude des paramètres sériques biochimiques: le cas des lapins (Néozélandais-Cunistar) de Côte d'Ivoire. Sciences et Nature, 2007;.4(1): 37-43
18. Djyh BN. Etude de l'évolution de quelques paramètres sériques marqueurs de la biotolérance de trois phytomédicaments. Thèse de Doctorat 3è cycle, UFR Biosciences, Université, Cocody-Abidjan, 2003; p 144.
19. Xavier L. Rôle du foie dans le métabolisme des nutriments en nutrition artificielle. Nutrition clinique et métabolisme, 1999; 13(4): 225-231
20. Eastham RD. Abrégé de constantes biologiques. Edition Masson, Paris-France; 1978; p 248