Validation and application of reversed phase high-performance liquid chromatographic method for quantification of pizotifen malate in pharmaceutical solid dosage formulations

Pakistan Journal of Pharmaceutical Sciences

Volumn 23, Issue 4, 2010, Pages 435-441

  Rahman, Shaikh Mukidur ^a   Kabir, Abul Kalam Lutful ^a   Jahan, Arshad ^b   Momen, Azm Ruhul ^c   Rouf, Abu Shara Shamsur ^a  

^a UNIVERSITY OF DHAKA   (Bangladesh)

^b Square Pharmaceuticals Ltd ^*  (Bangladesh)

^c JAGANNATH UNIVERSITY   (Bangladesh)

Author keywords

Chromatography; Pizotifen malate; Placebo study; Sedating antihistamine; System suitability; Ultraviolet detection

Indexed keywords

ACETIC ACID; ACETONITRILE; PIZOTIFEN; PLACEBO;

ACCURACY; ANALYTIC METHOD; ARTICLE; DRUG DOSAGE FORM; DRUG FORMULATION; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY ANALYSIS; SOLID STATE; VALIDATION PROCESS;

CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSAGE FORMS; INDICATORS AND REAGENTS; PIZOTYLINE; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; SEROTONIN ANTAGONISTS; SOLUTIONS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 78651406842     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. British Pharmacopoeia (2009). Monographs: Medicinal and Pharmaceutical Substances, Pizitifen malate, Volume I & II.
2. Dessouky YM, Hassanein HH, Mohammad MAA and Hanafy RS (2004). Spectrophotometric and spectrofluorimetric determination of pizotifen malate. Bull. Fac. Pharm. Cairo Univ ., 42(1): 41-51.
3. El-Kousy N and Bebawy LI (1999). Determination of some antihistaminic drugs by atomic absorption spectrometry and colorimetric methods. J. Pharmaceut. Biomed., 20: 671-679.
4. Fronza M, Junior LB, Wrasse M, Barth T and Dalmora SL (2006). Development and validation of a RP-HPLC Method for the Quantification and Dissolution Studies of Valdecoxib. Acta Farm. Bonaerense, 25(1): 117-122.
5. Ganesh M, Uppatyay S, Tivari R, Kamalakannan K, Rathinavel G, Gangully S and Sivakumar (2009). Quantitation of Alfuzosin Hydrochloride in Pharmaceutical Formulations by RP-HPLC. Pak. J. Pharm. Sci., 22(3): 263-266.
6. Guidelines for the Validation of Analytical Methods for Active Constituent, Agricultural and Veterinary Chemical Products, Australian Pesticides & Veterinary Medicines Authority, 2004.
7. Kazakevich Y and Lobrutto R (2007). HPLC for Pharmaceutical Scientists, John Wiley & Sons, Inc., New Jersey, pp.11.
8. st ed, Elsevier Inc., UK, pp.197-205.
9. th Ed., The Pharmaceutical Press, UK, p.624.
10. rd ed, Informa Healthcare USA, Inc., New York, p.526.
11. Stout TH and Dorsey JG (2001). High-Performance Liquid Chromatography. In: Ohannesian L, Streeter AJ (editors). Hand book of Pharmaceutical Analysis, Marcel Dekker, Inc., New York, p.138.