Identification of operationally tolerant liver transplant recipients

Liver Transplantation

Volumn 16, Issue SUPPL. 2, 2010, Pages

  Sánchez Fueyo, Alberto ^a,b,c  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GRAFT RECIPIENT; GRAFT REJECTION; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; LIVER TRANSPLANTATION; PRIORITY JOURNAL;

EID: 78651405845     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.22164     Document Type: Article

References (24)

1. Crispe IN,. Hepatic T cells and liver tolerance. Nat Rev 2003; 3: 51-62.
2. Starzl TE, Demetris AJ, Trucco M, Murase N, Ricordi C, Ildstad S, et al. Cell migration and chimerism after whole-organ transplantation: the basis of graft acceptance. Hepatology 1993; 17: 1127-1152. (Pubitemid 23187422)
3. Lerut J, Sanchez-Fueyo A,. An appraisal of tolerance in liver transplantation. Am J Transplant 2006; 6: 1774-1780. (Pubitemid 44024949)
4. Devlin J, Doherty D, Thomson L, Wong T, Donaldson P, Portmann B, Williams R,. Defining the outcome of immunosuppression withdrawal after liver transplantation. Hepatology 1998; 27: 926-933. (Pubitemid 28160476)
5. Mazariegos GV, Reyes J, Marino IR, Demetris AJ, Flynn B, Irish W, et al. Weaning of immunosuppression in liver transplant recipients. Transplantation 1997; 63: 243-249. (Pubitemid 27121206)
6. Pons JA, Yélamos J, Ramírez P, Oliver-Bonet M, Sánchez A, Rodríguez-Gago M, et al. Endothelial cell chimerism does not influence allograft tolerance in liver transplant patients after withdrawal of immunosuppression. Transplantation 2003; 75: 1045-1047. (Pubitemid 36438536)
7. Eason JD, Cohen AJ, Nair S, Alcantera T, Loss GE,. Tolerance: is it worth the risk? Transplantation 2005; 79: 1157-1159. (Pubitemid 40664015)
8. Takatsuki M, Uemoto S, Inomata Y, Egawa H, Kiuchi T, Fujita S, et al. Weaning of immunosuppression in living donor liver transplant recipients. Transplantation 2001; 72: 449-454. (Pubitemid 32769631)
9. Tisone G, Orlando G, Cardillo A, Palmieri G, Manzia TM, Baiocchi L, et al. Complete weaning off immunosuppression in HCV liver transplant recipients is feasible and favourably impacts on the progression of disease recurrence. J Hepatol 2006; 44: 702-709.
10. Tryphonopoulos P, Tzakis AG, Weppler D, Garcia-Morales R, Kato T, Madariaga JR, et al. The role of donor bone marrow infusions in withdrawal of immunosuppression in adult liver allotransplantation. Am J Transplant 2005; 5: 608-613. (Pubitemid 40313354)
11. Feng S,. Long-term management of immunosuppression after pediatric liver transplantation: is minimization or withdrawal desirable or possible or both? Curr Opin Organ Transplant 2008; 13: 506-512.
12. Scandling JD, Busque S, Dejbakhsh-Jones S, Benike C, Millan MT, Shizuru JA, et al. Tolerance and chimerism after renal and hematopoietic-cell transplantation. N Engl J Med 2008; 358: 362-368. (Pubitemid 351159235)
13. Kawai T, Cosimi AB, Spitzer TR, Tolkoff-Rubin N, Suthanthiran M, Saidman SL, et al. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 2008; 358: 353-361. (Pubitemid 351159234)
14. Yoshitomi M, Koshiba T, Haga H, Li Y, Zhao X, Cheng D, et al. Requirement of protocol biopsy before and after complete cessation of immunosuppression after liver transplantation. Transplantation 2009; 87: 606-614.
15. Mazariegos GV, Zahorchak AF, Reyes J, Ostrowski L, Flynn B, Zeevi A, Thomson AW,. Dendritic cell subset ratio in peripheral blood correlates with successful withdrawal of immunosuppression in liver transplant patients. Am J Transplant 2003; 3: 689-696. (Pubitemid 36745241)
16. Li Y, Koshiba T, Yoshizawa A, Yonekawa Y, Masuda K, Ito A, et al. Analyses of peripheral blood mononuclear cells in operational tolerance after pediatric living donor liver transplantation. Am J Transplant 2004; 4: 2118-2125. (Pubitemid 39611642)
17. Martínez-Llordella M, Puig-Pey I, Orlando G, Ramoni M, Tisone G, Rimola A, et al. Multiparameter immune profiling of operational tolerance in liver transplantation. Am J Transplant 2007; 7: 309-319. (Pubitemid 46096324)
18. Pons JA, Revilla-Nuin B, Baroja-Mazo A, Ramírez P, Martínez-Alarcõn L, Sánchez-Bueno F, et al. FoxP3 in peripheral blood is associated with operational tolerance in liver transplant patients during immunosuppression withdrawal. Transplantation 2008; 86: 1370-1378.
19. Jiang S, Lechler RI,. Regulatory T cells in the control of transplantation tolerance and autoimmunity. Am J Transplant 2003; 3: 516-524. (Pubitemid 36612834)
20. Puig-Pey I, Bohne F, Benítez C, Lõpez M, Martínez-Llordella M, Oppenheimer F, et al. Characterization of gammadelta T cell subsets in organ transplantation. Transpl Int; doi:10.1111/j.1432-2277.2010.01095.x.
21. Martínez-Llordella M, Lozano JJ, Puig-Pey I, Orlando G, Tisone G, Lerut J, et al. Using transcriptional profiling to develop a diagnostic test of operational tolerance in liver transplant recipients. J Clin Invest 2008; 118: 2845-2857.
22. Bohne F, Martínez-Llordella M, Lozano JJ, Lopez M, Benitez C, Miquel R, et al. Transcriptional profiling of liver grafts in spontaneous operational tolerance [abstract]. Accessed August 2010.
23. Girlanda R, Rela M, Williams R, O'Grady JG, Heaton ND,. Long-term outcome of immunosuppression withdrawal after liver transplantation. Transplant Proc 2005; 37: 1708-1709. (Pubitemid 40790804)
24. Assy N, Adams PC, Myers P, Simon V, Minuk GY, Wall W, Ghent CN,. Randomized controlled trail of total immunosuppression withdrawal in liver transplant recipients: role of ursodeoxycholic acid. Transplantation 2007; 83: 1571-1576. (Pubitemid 46987908)