Women and ischemic heart disease: Paradox and pathophysiology

JACC: Cardiovascular Imaging

Volumn 4, Issue 1, 2011, Pages 74-77

  Bairey Merz, C Noel ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

ischemic heart disease; microvascular coronary dysfunction; women

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 18; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANGINA PECTORIS; ANGIOCARDIOGRAPHY; AORTA ATHEROSCLEROSIS; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; CORONARY ARTERY DISEASE; CORONARY FLOW RESERVE; DIAGNOSTIC ERROR; DIAGNOSTIC TEST ACCURACY STUDY; DOPPLER ECHOCARDIOGRAPHY; FAMILY HISTORY; FEMALE; HEART INFARCTION; HEART MUSCLE BLOOD FLOW; HOSPITALIZATION; HUMAN; ISCHEMIC HEART DISEASE; METABOLIC SYNDROME X; MORTALITY; MYOCARDIAL PERFUSION IMAGING; NOTE; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; SEX DIFFERENCE; TRANSTHORACIC ECHOCARDIOGRAPHY;

EID: 78651403734     PISSN: 1936878X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcmg.2010.10.004     Document Type: Editorial

References (18)

1. L.J. Shaw, C.N. Bairey Merz, and C.J. Pepine Insights from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE) study Part I: gender differences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategies J Am Coll Cardiol 47 Suppl 2006 4 20
2. C.B. Merz, L. Shaw, and S. Reis Ischemic heart disease in women: insights from the NHLBI-sponsored Women's Ischemic Syndrome Evaluation (WISE) study Part II: sex differences in presentation diagnosis, and outcome with regard to sex-based pathophysiology of atherosclerosis, maco and microvascular CAD J Am Coll Cardiol 47 Suppl 2006 21 29
3. C.N. Merz, S.F. Kelsey, and C.J. Pepine The Women's Ischemia Syndrome Evaluation (WISE) study: protocol design, methodology and feasibility report J Am Coll Cardiol 33 1999 1453 1461
4. M. Gulati, R.M. Cooper-DeHoff, and C. McClure Adverse cardiovascular outcomes in women with nonobstructive coronary artery disease: a report from the Women's Ischemia Syndrome Evaluation Study and the St James Women Take Heart Project Arch Intern Med 169 2009 843 850
5. C.J. Pepine, R.D. Anderson, and B.L. Sharaf Coronary microvascular reactivity to adenosine predicts adverse outcome in women evaluated for suspected ischemia results from the National Heart, Lung and Blood Institute WISE (Women's Ischemia Syndrome Evaluation) study J Am Coll Cardiol 55 2010 2825 2832
6. M. Doyle, N. Wienberg, and G.M. Pohost Prognostic value of global MR myocardial perfusion imaging in women with suspected myocardial ischemia and no obstructive coronary disease: results from the NHLBI-sponsored WISE (Women's Ischemia Syndrome Evaluation) study J Am Coll Cardiol Img 3 2010 1030 1036
7. J.G. Cleland, D. Pennel, and S. Ray The Carvedilol Hibernation Reversible Ischaemia Trial; Marker of Success (CHRISTMAS) The CHRISTMAS Study Steering Committee and Investigators Eur J Heart Fail 1 1999 191 196
8. S.D. Buchthal, J.A. den Hollander, and C.N. Merz Abnormal myocardial phosphorus-31 nuclear magnetic resonance spectroscopy in women with chest pain but normal coronary angiograms N Engl J Med 342 2000 829 835
9. S.E. Reis, R. Holubkov, and J.S. Lee Coronary flow velocity response to adenosine characterizes coronary microvascular function in women with chest pain and no obstructive coronary disease Results from the pilot phase of the Women's Ischemia Syndrome Evaluation (WISE) study J Am Coll Cardiol 33 1999 1469 1475
10. T.R. Wessel, C.B. Arant, and S.P. McGorray Coronary microvascular reactivity is only partially predicted by atherosclerosis risk factors or coronary artery disease in women evaluated for suspected ischemia: results from the NHLBI Women's Ischemia Syndrome Evaluation (WISE) Clin Cardiol 30 2007 69 74
11. L.J. Shaw, R. Bugiardini, and C.N. Merz Women and ischemic heart disease: evolving knowledge J Am Coll Cardiol 54 2009 1561 1575
12. K. Banks, D. Puttagunta, and S. Murphy Clinical characteristics, vascular function, and inflammation in women with angina in the absence of coronary atherosclerosis: the Dallas Heart Study J Am Coll Cardiol Img 4 2011 65 73
13. R. Bugiardini, and C.N. Bairey Merz Angina with "normal" coronary arteries: a changing philosophy JAMA 293 2005 477 484
14. O.C. Marroquin, K.E. Kip, and S.R. Mulukutla Inflammation, endothelial cell activation, and coronary microvascular dysfunction in women with chest pain and no obstructive coronary artery disease Am Heart J 150 2005 109 115
15. B.D. Johnson, K.E. Kip, and O.C. Marroquin Serum amyloid A as a predictor of coronary artery disease and cardiovascular outcome in women: the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Circulation 109 2004 726 732
16. K.E. Kip, O.C. Marroquin, and L.J. Shaw Global inflammation predicts cardiovascular risk in women: a report from the Women's Ischemia Syndrome Evaluation (WISE) study Am Heart J 150 2005 900 906
17. B. Healy The Yentl syndrome N Engl J Med 325 1991 274 276
18. R. Bugiardini, O. Manfrini, C. Pizzi, F. Fontana, and G. Morgagni Endothelial function predicts future development of coronary artery disease: a study of women with chest pain and normal coronary angiograms Circulation 109 2004 2518 2523