Acute and sub-chronic oral toxicity studies of an aqueous stem bark extract of Pterocarpus soyauxii Taub (Papilionaceae) in rodents

Journal of Ethnopharmacology

Volumn 133, Issue 2, 2011, Pages 329-335

  Tchamadeu, M C ^a,b,c   Dzeufiet, P D D ^a   Nana, P ^a   Kouambou Nouga, C C ^a   Ngueguim Tsofack, F ^a   Allard, J ^b,c,d   Blaes, N ^b,c   Siagat, R ^a   Zapfack, L ^a   Girolami, J P ^b,c   Tack, I ^b,c,d   Kamtchouing, P ^a   Dimo, T ^a  

^a UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^b INSERM   (France)

^c UNIVERSITÉ DE TOULOUSE   (France)

^d UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

Acute and sub chronic toxicity; Aqueous stem bark extract; Blood analysis; Histopathology; Mortality; Pterocarpus soyauxii

Indexed keywords

PLANT EXTRACT; PLANT MEDICINAL PRODUCT; PTEROCARPUS SOYAUXII EXTRACT; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BARK; BEHAVIOR CHANGE; BIOCHEMICAL PARAMETERS; BODY WEIGHT; CHEMICAL PARAMETERS; CHRONIC TOXICITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG FATALITY; DRUG MEGADOSE; DRUG SAFETY; DRUG SCREENING; FEMALE; FLUID INTAKE; FOOD INTAKE; HEMATOLOGICAL PARAMETERS; HISTOPATHOLOGY; LD 50; LEGUME; LOW DRUG DOSE; MALE; MOUSE; MOUTH DISEASE; NONHUMAN; ORGAN WEIGHT; PLANT STEM; PTEROCARPUS SOYAUXII; SUBCHRONIC TOXICITY; TOXICITY TESTING;

ADMINISTRATION, ORAL; ANIMALS; BEHAVIOR, ANIMAL; CAMEROON; ETHNOPHARMACOLOGY; FEMALE; LETHAL DOSE 50; MALE; MEDICINE, AFRICAN TRADITIONAL; MICE; MICE, INBRED BALB C; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PLANT BARK; PLANT EXTRACTS; PLANTS, MEDICINAL; PTEROCARPUS; RATS; RATS, WISTAR;

MUS; PAPILIONOIDEAE; PTEROCARPUS SOYAUXII; RATTUS; RODENTIA;

EID: 78651396319     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.09.035     Document Type: Article

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