Hypoglycemic and antihyperglycemic effect of Witheringia solanacea in normal and alloxan-induced hyperglycemic rats

Journal of Ethnopharmacology

Volumn 133, Issue 2, 2011, Pages 907-910

  Herrera, Cristina ^a   García Barrantes, Pedro M ^a   Binns, Franklin ^a   Vargas, Marianela ^a   Poveda, Luis ^b   Badilla, Sandra ^a  

^a UNIVERSIDAD DE COSTA RICA   (Costa Rica)

^b UNIVERSIDAD NACIONAL   (Costa Rica)

Author keywords

Alloxan; Antidiabetic activity; Antihyperglycemic activity; Hypoglycemic activity; Solanaceae; Witheringia solanacea

Indexed keywords

ALLOXAN; ANTIDIABETIC AGENT; GLUCOSE; PLANT EXTRACT; UNCLASSIFIED DRUG; WITHERINGIA SOLANACEA EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG SYNTHESIS; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HYPERGLYCEMIA; MALE; NONHUMAN; PLANT LEAF; RAT;

ANIMALS; BLOOD GLUCOSE; COSTA RICA; DIABETES MELLITUS, EXPERIMENTAL; ETHNOPHARMACOLOGY; GLUCOSE TOLERANCE TEST; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; MALE; MEDICINE, TRADITIONAL; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; SOLANACEAE;

RATTUS; RODENTIA; SOLANACEAE; WITHERINGIA SOLANACEA;

EID: 78651382311     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.10.003     Document Type: Article

References (15)

1. F.J. Alarcon-Aguilara, R. Roman-Ramos, S. Pérez-Gutiérrez, A. Aguilar-Contreras, C.C. Contreras-Weber, and J.L. Flores-Saenz Study of the antihyperglycemic effect of plants used as antidiabetics Journal of Ethnopharmacology 61 1998 101 110
2. J.M. Barbosa-Filho, T. Vasconcelos, A.A. Alencar, L.M. Batista, R. Oliveira, D.N. Guedes, H.S. Falcão, M.D. Moura, M. Diniz, and J. Modesto-Filho Plants and their active constituents from South, Central, and North America with hypoglycemic activity Revista Brasileira de Farmacognosia 15 2005 392 413
3. L. Bohs Insights into Witheringia solanacea (Solanaceae) complex in Costa Rica. I. Breeding systems and crossing studies Biotropica 32 2000 70 79
4. J.P. Burke, K. Williams, K.M.V. Narayan, C. Leibson, S.M. Haffner, and M.P. Stern A population perspective on diabetes prevention: whom should we target for preventing weight gain? Diabetes Care 26 2003 1999 2004
5. C. Caballero-George, P.M.L. Vanderheyden, P.N. Solis, L. Pieters, A.A. Shahat, M.P. Gupta, G. Vauquelin, and A.J. Vlietinck Biological screening of selected medicinal Panamanian plants by radioligand-binding techniques Phytomedicine 8 2001 59 70
6. L. De la Torre, D. Alarcón, L.P. Kvist, and J. Salazar Usos medicinales de las plantas, Enciclopedia de las Plantas Útiles del Ecuador Herbario QCA and Herbario AAU 2008 105 114
7. W.C. Evans Trease and Evans' Pharmacognosy fifteenth edition 2002 Saunders Ltd. Edinburgh
8. M. García, P. Sánchez, L. Poveda, and M. Otárola Proyecto Etnobotánico del Caribe Norte de Costa Rica. Estación Biológica Caño Palma 2006 Universidad Nacional Autónoma de Costa Rica (UNA)
9. A. Gurib-Fakim Medicinal plants: traditions of yesterday and drugs of tomorrow Molecular Aspects of Medicine 27 2006 1 93
10. N.J. Jacobo-Herrera, P. Bremmer, N. Márquez, M.P. Gupta, S. Gibbons, E. Muñoz, and M. Heinrich Physalins from Witheringia solanacea as modulator of the NF-κB cascade Journal of Natural Products 69 2006 328 331
11. C.A. Lans Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus Journal of Ethnobiology and Ethnomedicine 2 2006 45
12. S. Lenzen The mechanisms of alloxan and streptozotocin induced diabetes Diabetologia 51 2008 216 226
13. O. Lock de Ugaz Segunda edition Investigación Fitoquímica: Métodos en el estudio de Productos Naturales 1994 Fondo Editorial de la Pontificia Universidad Católica del Perú Lima, Perú
14. J.L. Stone, and S.E. Pierce Rapid recent radiation of S-RNase lineages in Witheringia solanacea (Solanaceae) Heredity 94 2005 547 555
15. A.T. Vieira, V. Pinho, L.B. Lepsch, C. Scavone, I.M. Ribeiro, T. Tomassini, R. Ribeiro-dos-Santos, M.B.P. Soares, M.M. Teixeira, and D.G. Souza Mechanisms of the anti-inflammatory effects of the natural secosteroids physalins in a model of intestinal ischaemia and reperfusion injury British Journal of Pharmacology 146 2005 244 251