Novel treatment of onychomycosis using over-the-counter mentholated ointment: A clinical case series

Journal of the American Board of Family Medicine

Volumn 24, Issue 1, 2011, Pages 69-74

  Derby, Richard ^a   Rohal, Patrick ^b   Jackson, Constance ^c   Beutler, Anthony ^d   Olsen, Cara ^d  

^a Family Medicine Residency Program   (United States)

^b Malcolm Grow Medical Center ^*  (United States)

^c US Air Force 28th Medical Group   (United States)

^d Uniformed Services University of the Health Sciences   (United States)

Author keywords

Mentholated ointment; Onychomycosis; Treatment

Indexed keywords

ANTIFUNGAL AGENT; CAMPHOR DERIVATIVE; CAMPHOR PLUS EUCALYPTUS OIL PLUS MENTHOL PLUS THYMOL; EUCALYPTUS OIL; MENTHOL; NON PRESCRIPTION DRUG; POTASSIUM HYDROXIDE; THYMOL; UNCLASSIFIED DRUG; VAPORUB;

ADULT; AGED; ARTICLE; CANDIDA ALBICANS; CANDIDA PARAPSILOSIS; CASE STUDY; CLINICAL ARTICLE; CLINICAL ASSESSMENT; COST EFFECTIVENESS ANALYSIS; CRYPTOCOCCUS; DRUG EFFICACY; DRUG SAFETY; FEMALE; FOLLOW UP; FUNGUS CULTURE; FUSARIUM; HUMAN; MALE; NONHUMAN; OINTMENT; OUTCOME ASSESSMENT; PATIENT SATISFACTION; PENICILLIUM; PHOTOGRAPHY; PILOT STUDY; QUESTIONNAIRE; RATING SCALE; SCORING SYSTEM; TOENAIL ONYCHOMYCOSIS; TREATMENT DURATION; TRICHOPHYTON MENTAGROPHYTES; TRICHOPHYTON RUBRUM;

ADULT; AGED; AGED, 80 AND OVER; ANTI-INFECTIVE AGENTS, LOCAL; CAMPHOR; CANDIDA; DRUG COMBINATIONS; EUCALYPTUS; FEMALE; FOOT DERMATOSES; HEALTH STATUS INDICATORS; HUMANS; MALE; MENTHOL; MIDDLE AGED; NONPRESCRIPTION DRUGS; OINTMENTS; ONYCHOMYCOSIS; PATIENT SATISFACTION; PILOT PROJECTS; PLANT EXTRACTS; PROSPECTIVE STUDIES; QUESTIONNAIRES; STATISTICS AS TOPIC; TERPENES; THYMOL; TREATMENT OUTCOME;

EID: 78651370786     PISSN: 15572625     EISSN: 15587118     Source Type: Journal    
DOI: 10.3122/jabfm.2011.01.100124     Document Type: Article

References (15)

1. Gupta AK, Jain HC, Lynde CW, et al. Prevalence and epidemiology of onychomycosis in patients visiting physicians' offices: a multicenter Canadian survey of 15,000 patients. J Am Acad Dermatol 2000;43:244-8.
2. Erbagci Z, Tuncel A, Zer Y, Balci I. A prospective epidemiologic survey on the prevalence of onychomycosis and dermatophytosis in male boarding school residents. Mycopathologia 2005;159:347. (Pubitemid 40747828)
3. Ghannoum MA, Hajjeh RA, Scher R, et al. A largescale North American study of fungal isolates from nails: the frequency of onychomycosis, fungal distribution, and antifungal susceptibility patterns. J Am Acad Dermatol 2000;43:641-8.
4. Gupta AK, Jain HC, Lynde CW, Summerbell RC. Prevalence of unsuspected onychomycosis in patients visting dermatologists' offices in Ontario, Canada: a multicenter survey of 2001 patients. Int J Dermatol 1997;36:783-7.
5. Elewski BE, Charif MA. Prevalence of onychomycosis in patients attending a dermatology clinic in northeastern Ohio for other conditions. Arch Dermatol 1997;133:1172-3.
6. Drake LA, Patrick DL, Fleckman P, et al. The impact of onychomycosis on quality of life: development of an international onychomycosis questionnaire to measure patient quality of life. J Am Acad Dermatol 1999;41:189-96. (Pubitemid 29379702)
7. de Berker D. Fungal nail disease. N Engl J Med 2009;360:2108-16.
8. Gupta AK, Ryder JE, Johnson AM. Cumulative meta-analysis of systemic antifungal agents for the treatment of onychomycosis. Br J Dermatol 2004;150:537-44.
9. Gupta AK, Joseph WS. Ciclopirox 8% nail lacquer in the treatment of onychomycosis of the toenails in the United States. J Am Podiatr Med Assoc 2000;90:495-501.
10. Vicks VapoRub might help fight toenail fungus. Consum Rep 2006;71:49.
11. Pinto E, Pina-Vaz C, Salgueiro L, et al. Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species. J Med Microbiol 2006;55(Pt 10);1367-73. (Pubitemid 44349528)
12. Salgueiro LR, Pinto E, Goncalves MG, et al. Chemical composition and antifungal activity of the essential oil of Thymbra capitata. Planta Med 2004;70:572-5. (Pubitemid 38887919)
13. Pina-Vaz C, Goncalves Rodrigues A, Pinto E, et al. Antifungal activity of Thymus oils, and their essential compounds. J Eur Aca Dermatol Vernerol 2004;18:73-8. (Pubitemid 38159363)
14. Ramsewak RS, Nair MG, Stommel M, Selanders L. In vitro antagonistic activity of monoterpenes and their mixtures against "toe nail fungus" pathogens. Phytother Res 2003;17:376-9.
15. Lexi-Comp Reader version 2.4060407. Drug pricing information. Hudson, OH: Lexi-Comp, Inc.; 2006.