Reprogramming fibroblasts into cardiomyocytes

New England Journal of Medicine

Volumn 364, Issue 2, 2011, Pages 177-178

  Murry, Charles E ^a   Pu, William T ^b,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYOD1 PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CELL DIFFERENTIATION; FIBROBLAST; GENE EXPRESSION; HEART FAILURE; HEART MUSCLE CELL; HUMAN; MICROARRAY ANALYSIS; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL;

EID: 78651362485     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcibr1013069     Document Type: Article

References (4)

1. Ieda M, Fu JD, Delgado-Olguin P, et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 2010;142:375-86.
2. Davis RL, Weintraub H, Lassar AB. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 1987;51:987-1000.
3. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-76.
4. Murry CE, Kay MA, Bartosek T, Hauschka SD, Schwartz SM. Muscle differentiation during repair of myocardial necrosis in rats via gene transfer with MyoD. J Clin Invest 1996;98:2209-17.