Early goal-directed therapy in the management of severe sepsis/septic shock in an academic Emergency Department in Malaysia

Critical Care and Shock

Volumn 13, Issue 3, 2010, Pages 91-97

  Mohd Salleh, Farina ^a   Mohd Fathil, Shahridan ^a   Ahmad, Zulkernain ^a   Che'Man, Zuraidah ^a  

^a UNIVERSITI KEBANGSAAN MALAYSIA MEDICAL CENTER   (Malaysia)

Author keywords

Critical care; Early goal directed therapy; Emergency Department; Sepsis; Septic shock; Severe sepsis

Indexed keywords

LACTIC ACID;

ADULT; APACHE; ARTICLE; BLOOD CULTURE; BODY TEMPERATURE; BREATHING RATE; CARBON DIOXIDE TENSION; CENTRAL VENOUS CATHETERIZATION; CENTRAL VENOUS PRESSURE; CLINICAL ARTICLE; CLINICAL PROTOCOL; EARLY GOAL DIRECTED THERAPY; EMERGENCY WARD; FEMALE; HEART RATE; HEMODYNAMICS; HUMAN; LACTATE BLOOD LEVEL; LENGTH OF STAY; LEUKOCYTE COUNT; MALAYSIA; MALE; MEAN ARTERIAL PRESSURE; OXYGEN SATURATION; PROSPECTIVE STUDY; SEPSIS; SEPTIC SHOCK; SYSTOLIC BLOOD PRESSURE;

EID: 78651359580     PISSN: 14107767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001;29:1303-10.
2. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, et al. Early goaldirected therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-77.
3. Otero RM, Nguyen HB, Huang DT, Gaieski DF, Goyal M, Gunnerson KJ, et al. Early goal-directed therapy in severe sepsis and septic shock revisited: concepts, controversies, and contemporary fndings. Chest 2006;130:1579-95.
4. Trzeciak S, Dellinger RP, Abate NL, Cowan RM, Stauss M, Kilgannon JH, et al. Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department. Chest 2006;129:225-32.
5. Jones AE, Brown MD, Trzeciak S, Shapiro NI, Garrett JS, Heffner AC, et al. The effect of a quantitative resuscitation strategy on mortality in patients with sepsis: a metaanalysis. Crit Care Med 2008;36:2734-9.
6. Garcia AJ, Doshi P, Otero RM, Cannon CM, Rivers EP. Early sepsis management: a metaanalysis of published studies. Ann Emerg Med 2008;52: S59.
7. Gao F, Melody T, Daniels DF, Giles S, Fox S. The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study. Crit Care 2005;9: R764-70.
8. Jones AE, Focht A, Horton JM, Kline JA. Prospective external validation of the clinical effectiveness of an emergency departmentbased early goal-directed therapy protocol for severe sepsis and septic shock. Chest 2007;132:425-32.
9. McNeill G, Dixon M, Jenkins P. Can acute medicine units in the UK comply with the Surviving Sepsis Campaign's six-hour care bundle? Clin Med 2008;8:163-5.
10. Health Facts 2008. Health Informatics Centre. Planning and Development Division. Ministry of Health Malaysia [Online]. 2009 May 1 [cited 2010 Jul. 15]; Available from: URL: http://www.moh.gov. my/images/gallery/stats/heal-fact/ Health-Fact-2008-LANDSKAP.pdf