Anticancer drug-loaded nanospheres based on biodegradable amphiphilic ε-Caprolactone and carbonate copolymers

Pharmaceutical Research

Volumn 27, Issue 12, 2010, Pages 2743-2752

  Yan, Guo Ping ^a   Zong, Rong Feng ^a   Li, Liang ^a   Fu, Ting ^a   Liu, Fan ^a   Yu, Xiang Hua ^a  

^a WUHAN INSTITUTE OF TECHNOLOGY   (China)

Author keywords

Biodegradable polycarbonate; Copolymers; Drug controlled release; Nanospheres; Sulfadiazine

Indexed keywords

COPOLYMER; FLUOROURACIL; HYDROXYL GROUP; NANOSPHERE; POLY(CARBONATE ESTER) NANOSPHERE; POLYCAPROLACTONE; SULFADIAZINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIODEGRADABILITY; CANCER THERAPY; CELL STRAIN HEK293; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DIALYSIS; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG TARGETING; ELECTRIC POTENTIAL; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; NEBULIZATION; PRIORITY JOURNAL; STATIC ELECTRICITY; SYNTHESIS;

ANTINEOPLASTIC AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CARBONATES; CELL LINE; DRUG CARRIERS; DRUG SCREENING ASSAYS, ANTITUMOR; HEXANOIC ACIDS; HUMANS; LACTONES; MAGNETIC RESONANCE SPECTROSCOPY; NANOPARTICLES; POLYMERS;

EID: 78651323509     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0275-7     Document Type: Article

References (33)

1. Park K, Lee S, Kang E, Kim K, Choi K, Kwon IC. New generation of multifunctional nanoparticles for cancer imaging and therapy. Adv Funct Mater. 2009;19:1553-66.
2. Tokiwa Y, Calabia BP, Ugwu CU, Aiba S. Biodegradability of Plastics. Int J Mol Sci. 2009;10:3722-42.
3. Norowski PA, Bumgardner JD. Biomaterial and antibiotic strategies for peri-implantitis: A review. J Biomed Mater Res B Appl Biomater. 2009;88B(2):530-43.
4. Chawla JS, Amiji MM. Biodegradable poly(epsilon-caprolactone) nanoparticles for tumor-targeted delivery of tamoxifen. Int J Pharm. 2002;249:127-38.
5. Yan GP, Zhuo RX, Zheng CY. Study on the anticancer drug 5- fluorouracil-conjugated polyaspart-amides containing hepatocytetargeting group. J Bioact Compatible Polym. 2001;16(4):277-93.
6. Yan GP, Zhuo RX, Zhang X, Zhang X, Li LY, Liu ML. Tumorselective macromolecular MRI contrast agents. J Bioact Compatible Polym. 2002;17(2):139-51.
7. Yan GP, Zhuo RX. Research progress of magnetic resonance imaging contrast agents. Chin Sci Bull. 2001;46(7):531-8.
8. Yan GP, Li H, Bottle SE, Cheng SX, Wang XG, Yew YK, et al. Preparation, properties and mathematical modeling of microparticle drug delivery systems based on biodegradable amphiphilic tri-block copolymers. J Appl Polym Sci. 2004;92:3869-73.
9. Li H, Yan GP, Wu SN, Wang ZJ, Lam KY. Numerical simulation of controlled nifepine release from chitosan microspheres. J Appl Polym Sci. 2004;93:1928-37.
10. Yan GP, Peng L, Jian SQ, Li L, Bottle SE. Spin probes for electron paramagnetic resonance imaging. Chin Sci Bull. 2008;53 (24):3777-89.
11. Yan GP, Robinsonand L, Hogg P. Magnetic resonance imaging contrast agents: Overview and perspectives. Radiography. 2007;13:e5-19.
12. Yan GP, Zhuo RX, Zhang X, Xu MY, Li LY, Ye ZH. Hepatic targeting macromolecular MRI contrast agents. Polym Int. 2002;51:892-8.
13. Yan GP, Zhang JY, Zhou JX, Bottle SE, Yu XH, Wu JY, Li L. Targeted contrast agents for molecular imaging in magnetic resonance imaging (MRI). Recent Advances of Bioconjugate Chemistry in Molecular Imaging (ISBN 978-81-0210-7), Chen XY, Ed. 2008; Chapter 19: 371-98, Research Signpost, Kerala, India.
14. Liao LQ, Liu LJ, Zhang C, He F, Zhuo RX. Heating characteristics and polymerization of ε-caprolactone under microwave irradiation. J Appl Polym Sci. 2003;90:2657-64.
15. Barbault-Foucher S, Grefa R, Russo P. Design of poly-vepsilncaprolactone nanospheres coated with bioadhesive hyaluronic acid for ocular delivery. J Control Release. 2002;83:365-75.
16. Sun H, Mei L, Song C, Cui X, Wang P. The in vivo degradation, absorption and excretion of PCL-based implant. Biomaterials. 2006;27:1735-40.
17. Brown AH, Sheares VV. Amorphous unsaturated aliphatic polyesters derived from dicarboxylic monomers synthesized by diels-Alder chemistry. Macromolecules. 2007;40:4848-53.
18. Albertsson AC, Eklund M. Synthesis of copolymers of 1, 3-dioxan- 2-one and oxepan-2-one using coordination catalysts. J Polym Sci Part A Polym Chem. 1994;32:265-79.
19. Pego AP, Poot AA, Grijpma DW, Grijpma DW, Feijen J. Copolymers of trimethylene carbonate and epsilon-caprolactone for porous nerve guides: Synthesis and properties. J Biomater Sci Polym Ed. 2001;12:35-53.
20. Feng YK, Zhang SF. Hydrophilic-hydrophobic AB diblock copolymers containing poly(trimethylene carbonate) and poly (ethylene oxide) blocks. J Polym Sci Part A Polym Chem. 2005;43:4819-27.
21. Zurita R, Puiggali J, Franco L, Rodriguez-Galan A. Copolymerization of glycolide and trimethylene carbonate. J Polym Sci Part A: Polym Chem. 2006;44:993-1013.
22. Dobrzynski P, Kasperczyk J. Synthesis of biodegradable copolymers with low-toxicity zirconium compounds. V. multiblock and random copolymers of L-lactide with trimethylene carbonate obtained in copolymerizations initiated with zirconium( IV) acetylacetonate. J Polym Sci Part A: Polym Chem. 2006;44:3184-201.
23. Hu B, Yan GP, Zhuo RX, Wu Y, Fan CL. Polycarbonate microspheres containing tumor necrosis factor-a genes and magnetic powder as potential cancer therapeutics. J Appl Polym Sci. 2008;107(5):3343-9.
24. Kricheldorf HR, Weegen-Schulz B. Polymers of carbonic acid 11. reactions and polymerizations of aliphatic cyclocarbonates with boron halides. Macromolecules. 1993;26:5991-5.
25. Kricheldorf HR, Weegen-Schulz B. Polymers of carbonic acid. XIV. high molecular weight poly(trimethylene carbonate) by ringopening polymerization with butyltin chlorides as initiators. J Polym Sci Polym Chem. 1995;33(13):2193-201.
26. Matsuo J, Aoki K, Sanda F, Endo T. Substituent effect on the anionic equilibrium polymerization of six-membered cyclic carbonates. Macromolecules. 1998;31:4432-8. (Pubitemid 128567880)
27. Liu ZL, Zhang JM, Zhuo RX. Synthesis and characterization of functional polycarbonates. Chem J Chin Universities. 2003;24 (9):1730-2.
28. Mei LL, Yan GP, Yu XH, Yu XH, Cheng SX, Wu JY. Ringopening copolymerization and properties of polycarbonate copolymers. J Appl Polym Sci. 2008;108:93-8.
29. Chen H, Yan GP, Li L, Ai CW, Yu XH, Wu JY. Synthesis, characterization and properties of e-caprolactone and carbonate copolymers. J Appl Polym Sci. 2009;114(5):3087-96.
30. Lu K, Yan GP, Chen H, Li L, Ai CW, Yu XH. Microwave-assisted ring-opening copolymerization of e-caprolactone and 2-phenyl-5, 5- bis(oxymethyl) trimethylene carbonate. Chin Sci Bull. 2009;54 (18):3237-43.
31. Huang JL, Wang HY, Zhou CL. Ring-opening polymerization of ethylene oxide by anion initiation using sulfadiazine as parent compound. J Appl Polym Sci. 1995;58:8-11.
32. Yan GP, Zheng CY, Cao W, Li W, Li LY, Liu ML, et al. Synthesis and preliminary evaluation of gadolinium complexes containing sulfonamide groups as potential MRI contrast agents. Radiography. 2003;9:35-41.
33. Yan GP, Liu ML, Li LY. Studies on polyaspartamide gadolinium complexes containing sulfadiazine groups as MRI contrast agents. Bioconjug Chem. 2005;16:967-71.