Memory impairment in rats by hippocampal administration of the serine protease subtilisin

Behavioural Brain Research

Volumn 219, Issue 1, 2011, Pages 63-67

  Kornisiuk, Edgar ^a   Snitcofsky, Marina ^a   Blanco, Carlos ^a   Harvey, Alan L ^b   Stone, Trevor W ^c   Jerusalinsky, Diana ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Avoidance; Hippocampus; Memory; Proteases; Subtilisin

Indexed keywords

SERINE PROTEINASE INHIBITOR; SUBTILISIN;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVOIDANCE BEHAVIOR; CONTROLLED STUDY; FOOTSHOCK; HIPPOCAMPUS; LEARNING DISORDER; LONG TERM DEPRESSION; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; NONHUMAN; PRIORITY JOURNAL; RAT; STIMULUS RESPONSE; TASK PERFORMANCE;

ANIMALS; AVOIDANCE LEARNING; CEREBRAL HEMORRHAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROSHOCK; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; INJECTIONS; MALE; MEMORY; MEMORY DISORDERS; MOTOR ACTIVITY; RATS; RATS, WISTAR; SERINE PROTEINASE INHIBITORS; SUBTILISIN;

EID: 78651322627     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2010.12.027     Document Type: Article

References (16)

1. Qian Z., Gilbert M.E., Colico M.A., Kandel E.R., Kuhl D. Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation. Nature 1993, 361:453-457.
2. Chen Z.-L., Yoshida S., Kato K., Momata Y., Suzuki J., Tanaka T., et al. Expression and activity-dependent changes of a novel limbic serine protease gene in the hippocampus. J Neurosci 1995, 15:5088-5097.
3. Shimizu C., Yoshida S., Shibata M., Kato K., Momota Y., Matsumoto K., et al. Characterization of recombinant and brain neuropsin, a plasticity-related serine protease. J Biol Chem 1998, 273:11189-11196.
4. Komai S., Matsuyama T., Matsumoto K., Kato K., Kobayashi M., Imamura K., et al. Neuropsin regulates an early phase of Schaffer-collateral long-term potentiation in the murine hippocampus. Eur J Neurosci 2000, 12:1479-1486.
5. Tamura H., Ishikawa Y., Hino N., Maeda M., Yoshida S., Kaku S., et al. Neuropsin is essential for early processes of memory acquisition and Schaffer collateral long-term potentiation in adult mouse hippocampus in vivo. J Physiol (Lond) 2006, 570:541-551.
6. Frischnecht R., Fejtova A., Viesti M., Stephan A., Sonderegger P. Activity-induced synaptic capture and exocytosis of the neuronal serine protease neurotrypsin. J Neurosci 2008, 28:1568-1579.
7. Kemp A., Manahan-Vaughan D. Hippocampal long-term depression and long-term potentiation encode different aspects of novelty acquisition. Proc Nat Acad Sci USA 2004, 101:8192-8197.
8. MacGregor D.G., Mallon A.P., Harvey A.L., Young L., Nimmo H.G., Stone T.W. Group S8A serine proteases, including a novel enzyme cadeprin, induce long-lasting, metabotropic glutamate receptor-dependent synaptic depression in rat hippocampal slices. Eur J Neurosci 2007, 26:1870-1880.
9. Monard D. Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth. Trends Neurosci 1988, 11:541-544.
10. Hirata A., Yoshida S., Inoue N., Matsumoto-Miyai K., Ninomiya A., Taniguchi M., et al. Abnormalities of synapses and neurons in the hippocampus of neuropsin-deficient mice. Mol Cell Neurosci 2001, 17:600-610.
11. Diamandis E.P., Scorilas A., Kishi T., Blennow K., Luo L.Y., Soosaipillai A., et al. Altered kallikrein 7 and 10 concentrations in cerebrospinal fluid of patients with Alzheimer's disease and frontotemporal dementia. Clin Biochem 2004, 37:230-237.
12. Vawter M.P., Weickert C.S., Ferran E., Matsumoto M., Overman K., Hyde T.M., et al. Gene expression of metabolic enzymes and a protease inhibitor in the prefrontal cortex are decreased in schizophrenia. Neurochem Res 2004, 29:1245-1255.
13. Paxinos G., Watson C. The rat brain in stereotaxic coordinates 1998, Academic Press, San Diego. 4th ed.
14. Blake M.G., Boccia M.M., Baratti C.M. Behavioral differences on memory retrieval between two variants of step-through inhibitory avoidance task in mice. Neurosci Lett 2008, 444:102-105.
15. Martel G., Jaffard R., Guillou J.-L. Identification of hippocampus-dependent and hippocampus-independent memory components in step-down inhibitory avoidance tasks. Behav Brain Res 2010, 207:138-143.
16. Molinari F., Rio M., Meskenaite V., Encha-Razavi F., Auge J., Bacq D., et al. Truncating neurotrypsin mutation in autosomal recessive non-syndromic mental retardation. Science 2002, 298:1779-1781.