Behavioral deficit and decreased GABA receptor functional regulation in the hippocampus of epileptic rats: Effect of bacopa monnieri

Neurochemical Research

Volumn 36, Issue 1, 2011, Pages 7-16

  Mathew, Jobin ^a   Gangadharan, Gireesh ^a   Kuruvilla, Korah P ^a   Paulose, C S ^a  

^a Department of Physics   (India)

Author keywords

Bacopa monnieri; Bacoside A; Carbamazepine; Epilepsy; Pilocarpine

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA1; 4 AMINOBUTYRIC ACID RECEPTOR; ANTICONVULSIVE AGENT; BACOPA MONNIERI EXTRACT; BACOSIDE A; CARBAMAZEPINE; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR DISORDER; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EPILEPSY; GENE EXPRESSION; HIPPOCAMPUS; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TEMPORAL LOBE EPILEPSY;

ANIMALS; ANTICONVULSANTS; BACOPA; BEHAVIOR, ANIMAL; CARBAMAZEPINE; EPILEPSY; HIPPOCAMPUS; MALE; NEUROPSYCHOLOGICAL TESTS; PLANT EXTRACTS; RATS; RATS, WISTAR; RECEPTORS, GABA; SAPONINS; TRITERPENES;

BACOPA MONNIERI; RATTUS; SCROPHULARIACEAE;

EID: 78651286983     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-010-0253-9     Document Type: Article

References (67)

1. A receptor-mediated inhibition J Physiol 562 37 46 1:CAS:528: DC%2BD2MXotlelsQ%3D%3D 10.1113/jphysiol.2004.077362 15528237 (Pubitemid 40207782)
2. K Tsunashima C Schwarzer E Kirchmair W Sieghart G Sperk 1997 GABA(A) receptor subunits in the rat hippocampus III: altered messenger RNA expression in kainic acid-induced epilepsy Neuroscience 80 1019 1032 1:CAS:528: DyaK2sXls1Ojsr8%3D 10.1016/S0306-4522(97)00144-9 9284057 (Pubitemid 27359789)
3. AR Brooks-Kayal MD Shumate H Jin TY Rikhter DA Coulter 1998 Selective changes in single cell GABA(A) receptor subunit expression and function in temporal lobe epilepsy Nat Med 4 1166 1172 1:CAS:528:DyaK1cXms1Ggt78%3D 10.1038/2661 9771750 (Pubitemid 28468830)
4. A receptor subtypes in human temporal lobe epilepsy J Neurosci 20 5401 5419 1:CAS:528:DC%2BD3cXlt1Wiu78%3D 10884325
5. S Baulac G Huberfeld I Gourfinkel-An G Mitropoulou A Beranger JF Prud'homme M Baulac A Brice R Bruzzone E LeGuern 2001 First genetic evidence of GABA(A) receptor dysfunction in epilepsy: a mutation in the gamma2-subunit gene Nat Genet 28 46 48 1:CAS:528:DC%2BD3MXjt1Wqu70%3D 10.1038/88254 11326274 (Pubitemid 32405815)
6. RH Wallace C Marini S Petrou LA Harkin DN Bowser RG Panchal DA Williams GR Sutherland JC Mulley IE Scheffer SF Berkovic 2001 Mutant GABA(A) receptor gamma2-subunit in childhood absence epilepsy and febrile seizures Nat Genet 28 49 52 1:CAS:528:DC%2BD3MXjt1Wqu7o%3D 10.1038/88259 11326275 (Pubitemid 32405816)
7. P Cossette L Liu K Brisebois H Dong A Lortie M Vanasse JM Saint-Hilaire L Carmant A Verner WY Lu YT Wang GA Rouleau 2002 Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy Nat Genet 31 184 189 1:CAS:528:DC%2BD38XktVKgtr4%3D 10.1038/ng885 11992121
8. DS Olton BC Papas 1979 Spatial memory and hippocampal function Neuropsychologia 17 669 682 1:STN:280:DyaL3c%2FpvF2nsg%3D%3D 10.1016/0028-3932(79)90042-3 522981 (Pubitemid 10167907)
9. BB Rosane MT Helena 2004 Carbamazepine enhances discriminative memory in rat model of epilepsy Epilepsia 45 1443 1447 10.1111/j.0013-9580.2004.52403.x (Pubitemid 39470048)
10. P Kwan MJ Brodie 2001 Neuropsychological effects of epilepsy and antiepileptic drugs Lancet 357 216 222 1:STN:280:DC%2BD3M7kvFChuw%3D%3D 10.1016/S0140-6736(00)03600-X 11213111 (Pubitemid 32108114)
11. Martin S, Jones M, Simpson E, Van den Buuse M (2003) Impaired spatial reference memory in aromatase-deficient (ArKO) mice. Neuroreport 14:1979-1982
12. CD Conrad KA Grote RJ Hobbs A Ferayorni 2003 Sex differences in spatial and non-spatial Y-maze performance after chronic stress Neurobio Learn Mem 79 32 40 10.1016/S1074-7427(02)00018-7 (Pubitemid 36071188)
13. CD Conrad SJ Lupien LC Thanasoulis BS McEwen 1997 The effects of type I and type II corticosteroid receptor agonists on exploratory behavior and spatial memory in the Y-maze Brain Res 759 76 83 1:CAS:528:DyaK2sXjtlWgtLk%3D 10.1016/S0006-8993(97)00236-9 9219865 (Pubitemid 27286346)
14. LS Leung KA Boon T Kaibara NK Innis 1990 Radial maze per-formance following hippocampal kindling Behav Brain Res 40 119 129 1:STN:280: DyaK3M7js1Ohsg%3D%3D 10.1016/0166-4328(90)90004-X 2285473 (Pubitemid 20369877)
15. Qing LI, Chun lJ, Li-sha XU, Zheng-bin ZG, Li-xia Y, Lu-ying L, Zhong C (2005) Histidine enhances carbamazepine action against seizures and improves spatial memory deficits induced by chronic transauricular kindling in rats. Acta Pharmacologica Sinica 26:1297-1302
16. A Russo AA Izzo F Borrelli M Renis A Vanella 2003 Free radical scavenging capacity and protective effect of Bacopa monniera L. on DNA damage Phytother Res 17 46 54 10.1002/ptr.1061 (Pubitemid 37152749)
17. HK Sing BN Dhawan 1997 Neuropsychopharmacological effects of the Ayurvedic nootropic Bacopa monniera Linn. (Brahmi) Indian J Pharmacol 29 359 365
18. A Russo F Borrelli 2005 Bacopa monniera, a reputed nootropic plant: an overview Phytomedicine 12 305 317 1:CAS:528:DC%2BD2MXlvVGhtrw%3D 10.1016/j.phymed.2003.12.008 15898709 (Pubitemid 40471030)
19. RH Singh L Singh 1980 Studies on the anti-anxiety effect of the medhya rasayana drug, Brahmi (Bacopa monniera Wettst.) -part 1 J Res Ayurveda Siddha 1 133 148
20. HK Singh BN Dhawan 1982 Effect of Bacopa monniera Linn. (brahmi) extract on avoidance responses in rat J Ethnopharmacol 5 205 214 1:STN:280: DyaL387itlKitA%3D%3D 10.1016/0378-8741(82)90044-7 7057659 (Pubitemid 12126680)
21. Singh HK, Dhawan BN (1992) Drugs affecting learning and memory. In: Tandon PN, Bijiani V, Wadhwa S (eds) Lectures in neurobiology, vol 1. Wiley Eastern, New Delhi, pp 189-207
22. M Deepak A Amit 2004 The need for establishing identities of 'bacoside A and B', the putative major bioactive saponins of Indian medicinal plant Bacopa monnieri Phytomedicine 11 264 268 1:CAS:528:DC%2BD2cXjsFyksb8%3D 10.1078/0944-7113-00351 15070183 (Pubitemid 38314071)
23. Mathew J, Paul J, Nandhu MS, Paulose CS (2009) Bacopa monnieri and Bacoside-A for ameliorating epilepsy associated behavioral deficits. Fitoterapia. PMID: 19944749
24. CS Paulose F Chathu SK Reas A Krishnakumar 2008 Neuroprotective role of bacopa monnieri extract in epilepsy and effect of glucose supplementation during hypoxia: glutamate receptor gene expression Neurochem Res 33 1573 6903 10.1007/s11064-007-9513-8
25. RJ Racine 1972 Modification of seizure activity by electrical stimulation. After discharge threshold Electroencephalogr Clin Neurophysiol 32 269 279 1:STN:280:DyaE387gvFClsQ%3D%3D 10.1016/0013-4694(72)90176-9 4110396
26. OH Lowry N Roserbbrough AL Farr RJ Randall 1951 Protein measurement with Folin phenol reagent J Biol Chem 193 265 275 1:CAS:528:DyaG38XhsVyrsw%3D%3D 14907713
27. S Kurioka K Toshiaki M Makoto 1981 Effect of Sodim and Bicarbonate Ions on GABA Receptor binding in synaptic membrane of rat brain J Neurochem 37 418 421 1:CAS:528:DyaL3MXltV2jsL8%3D 10.1111/j.1471-4159.1981.tb00471.x 6267202 (Pubitemid 11059457)
28. G Scatchard 1949 The attractions of proteins for small molecules and ions Ann NY Acad Sci 51 660 672 1:CAS:528:DyaH1MXktFGktw%3D%3D 10.1111/j.1749-6632. 1949.tb27297.x
29. MX Ma YM Chen J He T Zeng JH Wang 2007 Effects of morphine and its withdrawal on Y-maze spatial recognition memory in mice Neuroscience 147 1059 1065 1:CAS:528:DC%2BD2sXotlSltLg%3D 10.1016/j.neuroscience.2007.05.020 17601672 (Pubitemid 47102553)
30. Y Akwa N Ladurelle DF Covey EE Baulieu 2001 The synthetic enantiomer of pregnenolone sulfate is very active on memory in rats and mice, even more so than its physiological neurosteroid counterpart: distinct mechanisms? Proc Natl Acad Sci USA 98 14033 14037 1:CAS:528:DC%2BD3MXovVynu7k%3D 10.1073/pnas. 241503698 11717462 (Pubitemid 33116019)
31. VC Terra-Bustamante ÉR Coimbra KO Rezek SR Escorsi-Rosset R Guarnieri CL Dalmagro LM Inuzuka MM Bianchin L Wichert-Ana V Alexandre OM Takayanagui D Araújo AC dos Santos CG Carlotti R Walz HJ Markowitsch AC Sakamoto 2005 Cognitive performance of patients with mesial temporal lobe epilepsy and incidental calcified neurocysticercosis J Neurol Neurosurg Psychiatry 76 1080 1083 1:STN:280:DC%2BD2Mzms1ymsw%3D%3D 10.1136/jnnp.2004. 048934 16024883 (Pubitemid 41081280)
32. K Goffin J Nissinen LK Van 2007 Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat Exp Neurol 205 501 505 1:CAS:528:DC%2BD2sXls1ait7k%3D 10.1016/j.expneurol.2007.03.008 17442304 (Pubitemid 46755770)
33. M Glien C Brandt H Potschka W Loscher 2002 Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy Epilepsia 43 350 357 1:CAS:528:DC%2BD38XjtlSltbY%3D 10.1046/j.1528-1157.2002.18101.x 11952764 (Pubitemid 34297172)
34. J Hong W Heng O Gregory W Jianning D Kathleen S Di F Eric H Che-Chang D Richard W Kopke Jang-Yen 2003 Demonstration of functional coupling between γ-aminobutyric acid (GABA) synthesis and vesicular GABA transport into synaptic vesicles Proc Natl Acad Sci USA 100 4293 4298 10.1073/pnas.0730698100 (Pubitemid 36418196)
35. J Joseph B Niggemann KS Zaenker F Entschladen 2002 The neurotransmitter γ-aminobutyric acid is an inhibitory regulator for the migration of SW 480 colon carcinoma cells Cancer Res 22 6467 6469
36. P Lavenex DG Amaral 2000 Hippocampal-neocortical interaction: a hierarchy of associativity Hippocampus 10 420 430 1:STN:280:DC%2BD3M%2FmsFChtg%3D%3D 10.1002/1098-1063(2000)10:4<420::AID-HIPO8>3.0.CO;2-5 10985281
37. LR Squire CE Stark RE Clark 2004 The medial temporal lobe Annu Rev Neurosci 27 279 306 1:CAS:528:DC%2BD2cXmslant7k%3D 10.1146/annurev.neuro.27. 070203.144130 15217334 (Pubitemid 39050405)
38. DW Schulz RL Macdonald 1981 Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: correlation with anticonvulsant and anesthetic actions Brain Res 23 177 188 10.1016/0006-8993(81) 91179-3 (Pubitemid 11156793)
39. RL MacDonald JL Barker 1979 Enhancement of GABA-mediated postsynaptic inhibition in cultured mammalian spinal cord neurons: a common mode of anticonvulsant action Brain Res 167 323 336 1:CAS:528:DyaE1MXksV2gsLo%3D 10.1016/0006-8993(79)90826-6 445132 (Pubitemid 9149938)
40. KS Ashok AT Dennis 2000 Fetal hippocampal grafts containing CA3 cells restore host hippocampal glutamate decarboxylase-positive interneuron numbers in a rat model of temporal lobe epilepsy J Neuroscience 20 8788 8801
41. L Quan G Meili BS Chang DH Lowenstein 2003 Epilepsy N Engl J Med 349 1257 1266 10.1056/NEJMra022308 (Pubitemid 37152036)
42. D Gaffan 1994 Scene-specific memory for objects: a model of episodic memory impairment in monkeys with fornix transection J Cogn Neurosci 6 305 320 10.1162/jocn.1994.6.4.305
43. JP Aggleton MW Brown 1999 Episodic memory, amnesia, and the hippocampal-anterior thalamic axis Behav Brain Sci 22 425 444 1:STN:280:DC%2BD3M3ivFGgtQ%3D%3D 11301518
44. JP Aggleton D McMackin K Carpenter J Hornak N Kapur S Halpin 2000 Differential cognitive effects of colloid cysts in the third ventricle that spare or compromise the fornix Brain 123 800 815 10.1093/brain/123.4.800 10734011
45. A Daniel RO Levy LR Hopkins 2004 Squire Impaired odour recognition memory in patients with hippocampal lesions Learn Mem 11 794 796 10.1101/lm.82504 (Pubitemid 39602520)
46. W Godehard B Katrin I Eva 2004 Impaired associative memory in temporal lobe epilepsy subjects after lesions of hippocampus, parahippocampal gyrus, and amygdale Hippocampus 14 785 796 10.1002/hipo.10216 (Pubitemid 39220395)
47. R Rausch S Kraemer CJ Pietras M Le BG Vickrey EA Passaro 2003 Early and late cognitive changes following temporal lobe surgery for epilepsy Neurology 60 951 959 1:STN:280:DC%2BD3s7ktVWmsQ%3D%3D 12654959
48. RV Blake SJ Wroe EK Breen RA McCarthy 2000 Accelerated forgetting in patients with epilepsy Evidence for an impairment in memory consolidation Brain 123 472 483 10.1093/brain/123.3.472 10686171
49. CR Butler AZ Zeman 2008 Recent insights into the impairment of memory in epilepsy: transient epileptic amnesia, accelerated long-term forgetting and remote memory impairment Brain 131 243 263 10.1093/brain/awn127
50. A Stelzer G Simon G Kovacs R Rai 1994 Synaptic disinhibition during maintenance of long-term potentiation in the CA1 hippocampal subfield Proc Natl Acad Sci USA 91 3058 3062 1:CAS:528:DyaK2cXis1ajurY%3D 10.1073/pnas.91.8.3058 8159706
51. YM Lu IM Mansuy ER Kandel J Roder 2000 Calcineurin-mediated LTD of GABAergic inhibition underlies the increased excitability of CA1 neurons associated with LTP Neuron 26 197 205 1:CAS:528:DC%2BD3cXjtFSkt7s%3D 10.1016/S0896-6273(00)81150-2 10798404
52. CA Chapman JC Lacaille 1999 Cholinergic induction of theta-frequency oscillations in hippocampal inhibitory interneurons and pacing of pyramidal cell firing Neurosci 19 8637 8645 1:CAS:528:DyaK1MXmt1ejsLY%3D
53. CA Chapman JC Lacaille 1999 Intrinsic theta-frequency membrane potential oscillations in hippocampal CA1 interneurons of stratum lacunosum-moleculare J Neurophysiol 81 1296 1307 1:STN:280:DyaK1M7oslWquw%3D%3D 10085356
54. S Roodenrys D Booth S Bulzomi A Phipps C Micallef J Smoker 2002 Chronic effects of Brahmi (Bacopa monnieri) on human memory Neuropsychopharmacology 27 279 281 10.1016/S0893-133X(01)00419-5 12093601 (Pubitemid 34686978)
55. T Murugesan 2005 Evaluation of psychopharmacological effects of Linn Extract Phytomedicine 8 472 476 10.1078/S0944-7113(04)70068-9
56. HK Singh RP Rastogi RC Srimal BN Dhawan 1988 Effect of bacosides A and B on avoidance responses in rats Phytother Res 2 70 75 1:CAS:528: DyaL1cXls1ehu7s%3D 10.1002/ptr.2650020205 (Pubitemid 19038336)
57. HK Singh BN Dhawan 1982 Effect of Bacopa monniera Linn. (brahmi) extract on avoidance responses in rat J Ethnopharmacol 5 205 214 1:STN:280: DyaL387itlKitA%3D%3D 10.1016/0378-8741(82)90044-7 7057659 (Pubitemid 12126680)
58. SK Bhattacharya S Ghosal 1998 Anxiolytic activity of a standardized extract of Bacopa monniera-an experimental study Phytomedicine 5 77 82 1:CAS:528:DyaK1cXivFeqtrs%3D
59. K Sairam M Dorababu RK Goel SK Bhattacharya 2002 Antidepressant activity of standardized extract of Bacopa monniera in experimental models of depression in rats Phytomedicine 9 207 211 1:CAS:528:DC%2BD38Xlt1ejsbc%3D 10.1078/0944-7113-00116 12046860
60. C Stough J Lloyd J Clarke 2001 The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects Psychopharmacology 156 481 484 1:CAS:528:DC%2BD3MXmvVygurY%3D 10.1007/s002130100815 11498727 (Pubitemid 32695859)
61. Bhattacharya SK, Kumar A, Ghosal S (2000) Effect of Bacopa monniera on animal models of Alzheimer's disease and perturbed central cholinergic markers of cognition in rats. In: Siva Sanka DV (eds), Molecular aspects of Asian medicine. PJD Publications, New York
62. GK Ganguly CL Malhtora 1967 Some neuropharmacological and behavioral effects of an activefraction from Herpestis monniera Linn (Brahmi) Indian J Physiol Pharmacol 11 33 43 1:CAS:528:DyaF1MXksVyisrw%3D 5630157
63. PK Dey C Datta 1966 Effect of psychotropic phytochemicals on cerebral amino acid level Indian J Exp Biol 4 216 218 1:CAS:528:DyaF2sXksFejtA%3D%3D 5977555
64. SK Bhattacharya A Bhattacharya A Kumar S Ghosal 2000 Antioxidant activity of Bacopa monniera in rat frontal cortex, striatum and hippocampus Phytother Res 14 174 179 1:STN:280:DC%2BD3c3ns1agtQ%3D%3D 10.1002/(SICI)1099-1573(200005) 14:3<174::AID-PTR624>3.0.CO;2-O 10815010 (Pubitemid 30326010)
65. A Russo F Borrelli A Campisi 2003 Nitric oxide-related toxicity in cultured astrocytes: effect of Bacopa monnieri Life Sci 73 1517 1526 1:CAS:528:DC%2BD3sXlsVagtLY%3D 10.1016/S0024-3205(03)00476-4 12865091 (Pubitemid 36833284)
66. N Limpeanchob S Jaipan S Rattanakaruna W Phrompittayarat K Ingkaninan 2008 Neuroprotective effect of Bacopa monnieri on beta-amyloid-induced cell death in primary cortical culture J Ethnopharmacol 30 112 117 10.1016/j.jep.2008.07.039
67. DK Chowdhuri D Parmar P Kakkar 2002 Antistress effects of bacosides of Bacopa monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain Phytother Res 16 639 645 1:CAS:528:DC%2BD38XpsFKns70%3D 10.1002/ptr.1023 12410544 (Pubitemid 35334184)