Effects of alzheimer caregiving on allostatic load

Journal of Health Psychology

Volumn 16, Issue 1, 2011, Pages 58-69

  Roepke, Susan K ^a   Mausbach, Brent T ^b   Patterson, Thomas L ^b,c   Von Känel, Roland ^b,d   Ancoli Israel, Sonia ^e   Harmell, Alexandrea L ^a   Dimsdale, Joel E ^a   Aschbacher, Kirstin ^e   Mills, Paul J ^a   Ziegler, Michael G ^a   Allison, Matthew ^a   Grant, Igor ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^d UNIVERSITY OF BERN   (Switzerland)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

allostatic load; Alzheimer's disease; caregiving; chronic stress; coping

Indexed keywords

ADRENALIN; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; NORADRENALIN;

ADAPTIVE BEHAVIOR; AGED; ALLOSTASIS; ALZHEIMER DISEASE; ARTICLE; BLOOD; BLOOD PRESSURE; BODY MASS; CAREGIVER; CASE CONTROL STUDY; COST OF ILLNESS; DEPRESSION; FEMALE; HUMAN; MALE; MENTAL STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGIC TEST; PSYCHOLOGICAL ASPECT; PSYCHOLOGICAL RATING SCALE; STATISTICAL MODEL;

ADAPTATION, PSYCHOLOGICAL; AGED; ALLOSTASIS; ALZHEIMER DISEASE; BLOOD PRESSURE; BODY MASS INDEX; CAREGIVERS; CASE-CONTROL STUDIES; CHOLESTEROL; CHOLESTEROL, HDL; COST OF ILLNESS; DEPRESSION; EPINEPHRINE; FEMALE; HUMANS; LINEAR MODELS; MALE; NOREPINEPHRINE; PSYCHIATRIC STATUS RATING SCALES; PSYCHOLOGICAL TESTS; STRESS, PSYCHOLOGICAL;

EID: 78651257412     PISSN: 13591053     EISSN: 14617277     Source Type: Journal    
DOI: 10.1177/1359105310369188     Document Type: Article

References (59)

1. Andresen, E.M., Malmgren, J.A., Carter, W.B., & Patrick, D.L. (1994). Screening for depression in well older adults: Evaluation of a short form of the CES-D. American Journal of Preventive Medicine, 10, 77-84.
2. Aschbacher, K., Mills, P., von Känel, R., Hong, S., Mausbach, B., Roepke, S.,... Grant, I. (2008). Effects of depressive and anxious symptoms on norepinephrine and platelet P-selectin responses to acute psychological stress among elderly caregivers. Brain Behavior and Immunity, 22, 493-502.
3. Aschbacher, K., von Känel, R., Dimsdale, J.E., Patterson, T.L., Mills, P.J., Mausbach, B.T.,... Grant, I. (2006). Dementia severity of the care receiver predicts procoagulant response in Alzheimer caregivers. American Journal of Geriatric Psychiatry, 14, 694-703.
4. Baron, R.M., & Kenny, D.A. (1986). The moderator- mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. Journal of Personality & Social Psychology, 51, 1173-1182.
5. Bellingrath, S., Weigl, T., & Kudielka, B.M. (2009). Chronic work stress and exhaustion is associated with higher allostatic load in female school teachers. Stress, 12, 37-48.
6. Brown, D.E., James, G.D., & Mills, P.S. (2006). Occupational differences in job strain and physiological stress: Female nurses and school teachers in Hawaii. Psychosomatic Medicine, 68, 524-530.
7. Burns, D.D., Shaw, B.F., & Croker, W. (1987). Thinking styles and coping strategies of depressed women: An empirical investigation. Behaviour Research & Therapy, 25, 223-225.
8. Clark, M.S., Bond, M.J., & Hecker, J.R. (2007). Environmental stress, psychological stress, and allostatic load. Psychology, Health, & Medicine, 12, 18-30.
9. Cohen, S., Evans, G.W., Stokols, D., & Krantz, D.S. (1986). Behavior, health, and environmental stress. New York: Plenum Press.
10. Davidson, L.M., & Baum, A. (1986). Chronic stress and posttraumatic stress disorders. Journal of Consulting and Clinical Psychology, 54, 303-308.
11. DeGood, D.E. (1975). Cognitive control factors in vascular stress responses. Psychophysiology, 12, 399-401.
12. Dimsdale, J.E., & Ziegler, M.G. (1991). What do plasma and urinary measures of catecholamines tell us about human response to stressors? Circulation, 83 (4 (Suppl II )). 1136-42.
13. Doering, L.V., Dracup, K., Caldwell, M.A., Moser, D.K., Erickson, V.S., Fonarow, G., & Hamilton, M. (2004). Is coping style linked to emotional states in heart failure patients ? Journal of Cardiac Failure, 10, 344-349. (Pubitemid 39092688)
14. Elliot, A.F., Burgio, L.D., & DeCoster, J. (2010). Enhancing caregiver health: Findings from the Resources for Enhancing Alzheimer's Caregiver Health II Intervention. Journal of the American Geriatrics Society, 58, 30-37.
15. Glei, D.A., Goldman, N., Chuang, Y., & Weinstein, M. (2007). Do chronic stressors lead to physiological dysregulation? Testing the theory of allostatic load. Psychosomatic Medicine, 69, 769-776.
16. Glover, D.A., Stuber, M., & Poland, R.E. (2006). Allostatic load in women with and without PTSD symptoms. Psychiatry, 69, 191-203.
17. Gräsel, E. (1995). Somatic symptoms and caregiving strain among family caregivers of older patients with progressive nursing needs. Archives of Gerontology and Geriatrics, 21, 253-266.
18. Holmbeck, G.N. (2002). Post-hoc probing of significant moderational and mediational effects in studies of pediatric populations. Journal of Pediatric Psychology, 27 (1). 87-96.
19. Houston, B.K. (1972). Control over stress, locus of control, and response to stress. Journal of Personality and Social Psychology, 21, 249-255.
20. Janoff-Bulman, R., & Brickman, P. (1982). Expectations and what people learn from failure. Hillsdale, NJ: Erlbaum.
21. Karlamangla, A.S., Singer, B., McEwen, B.S., Rowe, J.W., & Seeman, T. (2002). Allostatic load as a predictor of functional decline: MacArthur studies of successful aging. Journal of Clinical Epidemiology, 55, 696-710.
22. Kennedy, B., & Ziegler, M.G. (1990). A more sensitive and specific radioenzymatic assay for catecholamines. Life Sciences, 47, 2143-2153.
23. Kiecolt-Glaser, J.K., Dura, J.R., Speicher, C.E., Trask, O.J., & Glaser, R. (1991). Spousal caregivers of dementia victims: Longitudinal changes in immunity and health. Psychosomatic Medicine, 53, 345-362.
24. Kiecolt-Glaser, J.K., Glaser, R., Gravenstein, S., Malarkey, W.B., & Sheridan, J. (1996). Chronic stress alters the immune response to influenza virus vaccine in older adults. Proceedings of the National Academy of Sciences of the United States of America, 93, 3043-3047.
25. Kubzansky, L.D., Kawachi, I., & Sparrow, D. (1999). Socioeconomic status, hostility, and risk factor clustering in the Normative Aging Study: Any help from the concept of allostatic load? Annals of Behavioral Medicine, 21, 330-338.
26. Mahoney, R., Regan, C., Katona, C., & Livingston, G. (2005). Anxiety and depression in family caregivers of people with Alzheimer disease: The LASER-AD study. American Journal of Geriatric Psychiatry, 13, 795-801.
27. Manuck, S.B., Harvey, A.H., Lechleiter, S.L., & Neal, K.S. (1978). Effects of coping on blood pressure, responses to threat or aversive stimulation. Psychophysiology, 15, 544-549.
28. Maselko, J., Kubzansky, L., Kawachi, I., Seeman, T.E., & Berkman, L. (2007). Religious service attendance and allostatic load among high-functioning elderly. Psychosomatic Medicine, 69, 464-472.
29. Mausbach, B.T., Coon, D.W., Patterson, T.L., & Grant, I. (2008 a). Engagement in activities is associated with affective arousal in Alzheimer's caregivers: A preliminary examination of the temporal relations between activity and affect. Behavior Therapy, 39, 366-374.
30. Mausbach, B.T., Dimsdale, J.E., Ziegler, M.G., Mills, P.J., Ancoli-Israel, S., Patterson, T.L., & Grant, I. (2005). Depressive symptoms predict norepinephrine response to a psychological stressor task in Alzheimer's caregivers. Psychosomatic Medicine, 67, 638-642.
31. Mausbach, B.T., Mills, P.J., Patterson, T.L., Aschbacher, K., Dimsdale, J.E., Ancoli-Israel, S.,... Grant, I. (2007 a). Stress-related reduction in personal mastery is associated with reduced immune cell beta2-adrenergic receptor sensitivity. International Psychogeriatrics, 19, 935-946.
32. Mausbach, B.T., Patterson, T.L., von Känel, R., Mills, P.J., Ancoli-Israel, S., Dimsdale, J.E., & Grant, I. (2006). Personal mastery attenuates the effect of caregiving stress on psychiatric morbidity. Journal of Nervous and Mental Disease, 194, 132-134.
33. Mausbach, B.T., Patterson, T.L., von Känel, R., Mills, P.J., Dimsdale, J.E., Ancoli-Israel, S., & Grant, I. (2007 b). The attenuating effect of personal mastery on the relations between stress and Alzheimer caregiver health: A five-year longitudinal analysis. Aging and Mental Health, 11, 637-644.
34. Mausbach, B.T., von Känel, R., Depp, C., Patterson, T.L., Aschbacher, K., Mills, P.J.,... Grant, I. (2008 b). The moderating effect of personal mastery on the relations between stress and Plasminogen Activator Inhibitor-1 (PAI-1) antigen. Health Psychology, 27 (2 Suppl.). S172 - S179.
35. McEwen, B.S. (2003). Mood disorders and allostatic load. Biological Psychiatry, 54, 200-207.
36. McEwen, B.S., & Stellar, E. (1993). Stress and the individual: Mechanisms leading to disease. Archives of Internal Medicine, 153, 2093-2101.
37. McNaughton, M.E., Patterson, T.L., Smith, T.L., & Grant, I. (1995). The relationship among stress, depression, locus of control, irrational beliefs, social support, and health in Alzheimer's disease caregivers. Journal of Nervous and Mental Disease, 183 (2). 78-85.
38. Mills, P.J., Adler, K.A., Dimsdale, J.E., Perez, C.J., Ziegler, M.G., Ancoli-Israel, S.,... Grant, I. (2004). Vulnerable caregivers of Alzheimer disease patients have a deficit in beta 2-adrenergic receptor sensitivity and density. American Journal of Geriatric Psychiatry, 12, 281-286.
39. Pearlin, L.I., Mullan, J.T., Semple, S.J., & Skaff, M.M. (1990). Caregiving and the stress process: An overview of concepts and their measures. The Gerontologist, 5, 583-594.
40. Pearlin, L.I., & Schooler, C. (1978). The structure of coping. Journal of Health and Social Behavior, 19, 2-21.
41. Pratt, C.C., Schmall, V.L., Wright, S., & Cleland, M. (1985). Burden and coping strategies of caregivers to Alzheimer's Patients. Family Relations, 34, 27-33.
42. Reuven-Magril, O., Dar, R., & Liberman, N. (2008). Illusion of control and behavioral control attempts in obsessive-compulsive disorder. Journal of Abnormal Psychology, 117, 334-341.
43. Roepke, S.K., Mausbach, B.T., Aschbacher, K., Ziegler, M.G., Dimsdale, J.E., Mills, P.J.,... Grant, I. (2008). Personal mastery is associated with reduced sympathetic arousal in stressed Alzheimer caregivers. American Journal of Geriatric Psychiatry, 16, 310-317.
44. Roepke, S.K., Mausbach, B.T., von Känel, R., Harmell, A.L., Ancoli-Israel, S., Dimsdale, J.E.,... Grant, I. (2009). The moderating role of personal mastery on the relationship between caregiver status and multiple dimensions of fatigue. International Journal of Geriatric Psychiatry, 12, 1453-1462.
45. Schulz, R., & Beach, S.R. (1999). Caregiving as a risk factor for mortality: The Caregiver Health Effects Study. JAMA: Journal of the American Medical Association, 282, 2215-2219.
46. Schulz, R., O'Brien, A.T., Bookwala, J., & Fleissner, K. (1995). Psychiatric and physical morbidity effects of dementia caregiving: Prevalence, correlates, and causes. The Gerontologist, 35, 771-791.
47. Seeman, T.E. (1991). Personal control and coronary artery disease: How generalized expectancies about control may influence disease risk. Journal of Psychosomatic Research, 35, 661-669.
48. Seeman, T.E., McEwen, B.S., Rowe, J.W., & Singer, B.H. (2001). Allostatic load as a marker of cumulative biological risk: MacArther studies of successful aging. Proceedings of the National Academy of Sciences of the United States of America, 98, 4770-4775.
49. Seeman, T.E., Singer, B.H., Rowe, J.W., Horwitz, R.I., & McEwen, B.S. (1997). Price of adaptation-allostatic load and its health consequences: MacArthur studies of successful aging. Archives of Internal Medicine, 157, 2259-2268.
50. Seeman, T.E., Singer, B.H., Ryff, C.D., Dienberg, L.G., & Levy-Storms, L. (2002). Social relationships, gender, and allostatic load across two age cohorts. Psychosomatic Medicine, 64, 395-406.
51. Shaw, W.S., Patterson, T.L., Ziegler, M.G., Dimsdale, J.E., Semple, S.J., & Grant, I. (1999). Accelerated risk of hypertensive blood pressure recordings among Alzheimer caregivers. Journal of Psychosomatic Research, 46, 215-277.
52. Singer, B., & Ryff, C. (1999). Hierarchies of life histories and associated health risks. Annals of the New York Academy of Sciences, 896, 96-115.
53. Singer, B., Ryff, C., & Seeman, T.E. (2004). Operationalizing allostatic load. In J. Schulkin (Ed.), Allostasis, homeostasis, and the cost of physiological adaptation (pp. 113-149). Cambridge: Cambridge University Press.
54. Vitaliano, P.P., Scanlan, J.M., Zhang, J., Savage, M.V., Hirsch, I.B., & Siegler, I.C. (2002). A path model of chronic stress, the metabolic syndrome, and coronary heart disease. Psychosomatic Medicine, 64, 418-435.
55. von Känel, R., Ancoli-Israel, S., Dimsdale, J.E., Mills, P.J., Mausbach, B.T., Ziegler, M.G.,... Grant, I. (2010). Sleep and biomarkers of atherosclerosis in elderly Alzheimer caregivers and controls. Gerontology, 56 (1). 41-50.
56. von Känel, R., Dimsdale, J.E., Adler, K.A., Patterson, T.L., Mills, P.J., & Grant, I. (2005). Exaggerated plasma fibrin formation (d-dimer) in elderly Alzheimer caregivers as compared to noncaregiving controls. Gerontology, 51, 7-13.
57. von Känel, R., Dimsdale, J.E., Mills, P.J., Ancoli-Israel, S., Patterson, T.L., Mausbach, B.T., & Grant, I. (2006). Effect of Alzheimer caregiving stress and age on frailty markers Interleukin-6, C-reactive protein, and d-dimer. Journals of Gerontology, Series A: Biological and Medical Sciences, 61A, 963-969.
58. Weinstein, M., Goldman, N., Hedley, A., Yu-Hsuan, L., & Seeman, T. (2003). Social linkages to biological markers of health among the elderly. Journal of Biosocial Science, 35, 433-453.
59. Weinstein, N.D. (1982). Unrealistic optimism about susceptibility to health problems. Journal of Behavioral Medicine, 5, 441-460.