Efficacy of Atovaquone and Azithromycin or Imidocarb Dipropionate in Cats with Acute Cytauxzoonosis

Journal of Veterinary Internal Medicine

Volumn 25, Issue 1, 2011, Pages 55-60

  Cohn, L A ^a   Birkenheuer, A J ^b   Brunker, J D ^c   Ratcliff, E R ^d   Craig, A W ^e  

^a UNIVERSITY OF MISSOURI   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c OKLAHOMA STATE UNIVERSITY   (United States)

^d Fair Grove Veterinary Services   (United States)

^e Lebanon Animal Hospital   (United States)

Author keywords

Antimicrobials; Clinical Trials; Microbiology; Molecular biology; Parasitology; PCR assays; Protozoa

Indexed keywords

ANTIPROTOZOAL AGENT; ATOVAQUONE; AZITHROMYCIN; DRUG DERIVATIVE; IMIDOCARB; IMIDOCARB DIPROPIONATE; PROTOZOAL DNA;

ANIMAL; ANIMAL DISEASE; ANIMAL PARASITOSIS; ARTICLE; CAT; CAT DISEASE; CHEMISTRY; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG COMBINATION; FEMALE; GENETICS; GENOTYPE; ISOLATION AND PURIFICATION; MALE; MULTICENTER STUDY; PARASITEMIA; PARASITOLOGY; PIROPLASMIDA; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; STATISTICAL MODEL; SURVIVAL;

ANIMALS; ANTIPROTOZOAL AGENTS; ATOVAQUONE; AZITHROMYCIN; CAT DISEASES; CATS; DNA, PROTOZOAN; DRUG THERAPY, COMBINATION; FEMALE; GENOTYPE; IMIDOCARB; LOGISTIC MODELS; MALE; PARASITEMIA; PIROPLASMIDA; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; PROTOZOAN INFECTIONS, ANIMAL; SURVIVAL ANALYSIS;

CYTAUXZOON FELIS; PROTOZOA;

EID: 78651255173     PISSN: 08916640     EISSN: 19391676     Source Type: Journal    
DOI: 10.1111/j.1939-1676.2010.0646.x     Document Type: Article

References (12)

1. Meinkoth J, Kocan AA, Whitworth L, et al. Cats surviving natural infection with Cytauxzoon felis: 18 cases (1997-1998). J Vet Intern Med 2000;14:521-525.
2. Greene CE, Latimer K, Hopper E, et al. Administration of diminazene aceturate or imidocarb dipropionate for treatment of cytauxzoonosis in cats. J Am Vet Med Assoc 1999;215:497-500.
3. Brown HM, Berghaus RD, Latimer KS, et al. Genetic variability of Cytauxzoon felis from 88 infected domestic cats in Arkansas and Georgia. J Vet Diag Invest 2009;21:59-63.
4. Haber MD, Tucker MD, Marr HS, et al. The detection of Cytauxzoon felis in apparently healthy free-roaming cats in the USA. Vet Parasitol 2007;146:316-320.
5. Brown HM, Latimer KS, Erikson LE, et al. Detection of persistent Cytauxzoon felis infection by polymerase chain reaction in three asymptomatic domestic cats. J Vet Diag Invest 2008;20:485-488.
6. Motzel SL, Wagner JE. Treatment of experimentally induced cytauxzoonosis in cats with parvaquone and buparvaquone. Vet Parasit 1990;35:131-138.
7. Brown HM, Lockhart JM, Latimer KS, et al. Identification and genetic characterization of Cytauxzoon felis in asymptomatic domestic cats and bobcats. Vet Parasitol 2010;172(3-4):311-316.
8. Greene CE, Meinkoth J, Kocan AA. Cytauxzoonosis. In: Greene GE, ed. Infectious Disease of the Dog and Cat, 3rd ed. St Louis, MO: Saunders Elsevier; 2006:716-722.
9. Birkenheuer AJ, Levy MG, Breitschwerdt EB. Efficacy of combined atovaquone and azithromycin for therapy of chronic Babesia gibsoni (Asian genotype) infections in dogs. J Vet Intern Med 2004;18:494-498.
10. Krause PJ, Lepore T, Sikand VK, et al. Atovaquone and azithromycin for the treatment of babesiosis. N Engl J Med 2000;343:1454-1458.
11. Birkenheuer AJ, Marr H, Alleman AR, et al. Development and evaluation of a PCR assay for the detection of Cytauxzoon felis DNA in feline blood samples. Vet Parasitol 2006;137:144-149.
12. Brown HM, Modaresi SM, Cook JL, et al. Genetic variability of archived Cytauxzoon felis histologic specimens from domestic cats in Georgia, 1995-2007. J Vet Diagn Invest 2009;21:493-498.