SCOPUS 정보 검색 플랫폼

Volumn 505, Issue 2, 2011, Pages 202-212

UMP kinase from Mycobacterium tuberculosis: Mode of action and allosteric interactions, and their likely role in pyrimidine metabolism regulation

(6) Rostirolla, Diana C a Breda, Ardala a Rosado, Leonardo A a Palma, Mario S b Basso, Luiz A a Santos, Diógenes S a

a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL (Brazil)

b SÃO PAULO STATE UNIVERSITY UNESP (Brazil)

Author keywords

Allosteric regulation; Antitubercular drug target; Cooperative kinetics; Pyrimidine metabolism; Thermodynamic binding parameters; UMPK

Indexed keywords

ADENOSINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATE; PHOSPHOTRANSFERASE; PYRIMIDINE; UNCLASSIFIED DRUG; URIDINE 5' MONOPHOSPHATE KINASE; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

AMINO ACID METABOLISM; ARTICLE; ENZYME KINETICS; ENZYME PHOSPHORYLATION; ESCHERICHIA COLI; GENE AMPLIFICATION; GENE SEQUENCE; MOLECULAR CLONING; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; CLONING, MOLECULAR; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENES, SUPPRESSOR; GUANOSINE TRIPHOSPHATE; KINETICS; LIGANDS; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; POLYMERASE CHAIN REACTION; PYRIMIDINES; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRANSFERASES; URIDINE TRIPHOSPHATE;

ESCHERICHIA COLI; EUKARYOTA; MYCOBACTERIUM TUBERCULOSIS;

EID: 78651254744 PISSN: 00039861 EISSN: 10960384 Source Type: Journal
DOI: 10.1016/j.abb.2010.10.019 Document Type: Article

Times cited : (13)

References (48)

1
- 0033581124
- C. Dye, S. Scheele, P. Dolin, V. Pathania, and M.C. Raviglione J. Am. Med. Assoc. 282 1999 677 686
- (1999) J. Am. Med. Assoc. , vol.282 , pp. 677-686
- Dye, C.¹ Scheele, S.² Dolin, P.³ Pathania, V.⁴ Raviglione, M.C.⁵

2
- 78651249958
- World Health Organization, Global Tuberculosis Control: A Short Update to the 2009 Report, 2010.
- (2010) World Health Organization, Global Tuberculosis Control: A Short Update to the 2009 Report

3
- 38049098158
- W.W. Yew, and C.C. Leung Respirology 13 2008 21 46
- (2008) Respirology , vol.13 , pp. 21-46
- Yew, W.W.¹ Leung, C.C.²

4
- 71049135360
- A.A. Velayati, P. Farnia, M.R. Masjedi, T.A. Ibrahim, P. Tabarsi, R.Z. Haroun, H.O. Kuan, J. Ghanavi, P. Farnia, and M. Varahram Eur. Respir. J. 34 2009 1202 1203
- (2009) Eur. Respir. J. , vol.34 , pp. 1202-1203
- Velayati, A.A.¹ Farnia, P.² Masjedi, M.R.³ Ibrahim, T.A.⁴ Tabarsi, P.⁵ Haroun, R.Z.⁶ Kuan, H.O.⁷ Ghanavi, J.⁸ Farnia, P.⁹ Varahram, M.¹⁰

5
- 33847705622
- R.G. Ducati, L.A. Basso, and D.S. Santos Curr. Drug Targets 8 2007 423 435
- (2007) Curr. Drug Targets , vol.8 , pp. 423-435
- Ducati, R.G.¹ Basso, L.A.² Santos, D.S.³

6
- 17244362388
- J.G. Robertson Biochemistry 44 2005 5561 5571
- (2005) Biochemistry , vol.44 , pp. 5561-5571
- Robertson, J.G.¹

7
- 36549063511
- J.G. Robertson Curr. Opin. Struct. Biol. 17 2007 674 679
- (2007) Curr. Opin. Struct. Biol. , vol.17 , pp. 674-679
- Robertson, J.G.¹

8
- 74149083849
- J.E. Ladbury, G.K. Klebe, and E. Freire Nat. Rev. Drug Discov. 9 2010 23 27
- (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 23-27
- Ladbury, J.E.¹ Klebe, G.K.² Freire, E.³

9
- 48749129111
- C. Meier, L.G. Carter, S. Sainsbury, E.J. Mancini, R.J. Owens, D.I. Stuart, and R.M. Esnouf J. Mol. Biol. 381 2008 1098 1105
- (2008) J. Mol. Biol. , vol.381 , pp. 1098-1105
- Meier, C.¹ Carter, L.G.² Sainsbury, S.³ Mancini, E.J.⁴ Owens, R.J.⁵ Stuart, D.I.⁶ Esnouf, R.M.⁷

10
- 0018412874
- G.E. Shambaugh Am. J. Clin. Nutr. 32 1979 1290 1297
- (1979) Am. J. Clin. Nutr. , vol.32 , pp. 1290-1297
- Shambaugh, G.E.¹

11
- 23944435947
- C. Marco-Marín, F. Gil-Ortiz, and V. Rubio J. Mol. Biol. 352 2005 438 454
- (2005) J. Mol. Biol. , vol.352 , pp. 438-454
- Marco-Marín, C.¹ Gil-Ortiz, F.² Rubio, V.³

12
- 17644435744
- H. Yan, and M.D. Tsai Adv. Enzymol. Relat. Areas Mol. Biol. 73 1999 103 134
- (1999) Adv. Enzymol. Relat. Areas Mol. Biol. , vol.73 , pp. 103-134
- Yan, H.¹ Tsai, M.D.²

13
- 21844477035
- P. Briozzo, C. Evrin, P. Meyer, L. Assairi, N. Joly, O. Barzu, and A. Gilles J. Biol. Chem. 280 2005 25533 25540
- (2005) J. Biol. Chem. , vol.280 , pp. 25533-25540
- Briozzo, P.¹ Evrin, C.² Meyer, P.³ Assairi, L.⁴ Joly, N.⁵ Barzu, O.⁶ Gilles, A.⁷

14
- 0028327709
- H.J. Müller-Dieckmann, and G.E. Schulz J. Mol. Biol. 236 1994 361 367
- (1994) J. Mol. Biol. , vol.236 , pp. 361-367
- Müller-Dieckmann, H.J.¹ Schulz, G.E.²

15
- 0037086275
- J. Liou, G.E. Dutschman, W. Lam, Z. Jiang, and Y. Cheng Cancer Res. 62 2002 1624 1631
- (2002) Cancer Res. , vol.62 , pp. 1624-1631
- Liou, J.¹ Dutschman, G.E.² Lam, W.³ Jiang, Z.⁴ Cheng, Y.⁵

16
- 0029785130
- K. Scheffzek, W. Kliche, L. Wiesmüller, and J. Reinstein Biochemistry 35 1996 9716 9727
- (1996) Biochemistry , vol.35 , pp. 9716-9727
- Scheffzek, K.¹ Kliche, W.² Wiesmüller, L.³ Reinstein, J.⁴

17
- 0028953772
- L. Serina, C. Blondin, E. Krin, O. Sismeiro, A. Danchin, H. Sakamoto, A.M. Gilles, and O. Bârzu Biochemistry 34 1995 5066 5074
- (1995) Biochemistry , vol.34 , pp. 5066-5074
- Serina, L.¹ Blondin, C.² Krin, E.³ Sismeiro, O.⁴ Danchin, A.⁵ Sakamoto, H.⁶ Gilles, A.M.⁷ Bârzu, O.⁸

18
- 0043270606
- C. Gagyi, N. Bucurenci, O. Sîrbu, G. Labesse, M. Ionescu, A. Ofiteru, L. Assairi, S. Landais, A. Danchin, O. Bârzu, and A. Gilles Eur. J. Biochem. 270 2003 3196 3204
- (2003) Eur. J. Biochem. , vol.270 , pp. 3196-3204
- Gagyi, C.¹ Bucurenci, N.² Sîrbu, O.³ Labesse, G.⁴ Ionescu, M.⁵ Ofiteru, A.⁶ Assairi, L.⁷ Landais, S.⁸ Danchin, A.⁹ Bârzu, O.¹⁰ Gilles, A.¹¹

19
- 10944266371
- F. Fassy, O. Krebs, M. Lowinski, P. Ferrari, J. Winter, and V. Collard-Dutilleul Biochem. J. 384 2004 619 627
- (2004) Biochem. J. , vol.384 , pp. 619-627
- Fassy, F.¹ Krebs, O.² Lowinski, M.³ Ferrari, P.⁴ Winter, J.⁵ Collard-Dutilleul, V.⁶

20
- 33947221897
- K.S. Jensen, E. Johansson, and K.F. Jensen Biochemistry 46 2007 2745 2757
- (2007) Biochemistry , vol.46 , pp. 2745-2757
- Jensen, K.S.¹ Johansson, E.² Jensen, K.F.³

21
- 36749044833
- L. Egeblad-Welin, M. Welin, L. Wang, and S. Eriksson FEBS J. 274 2007 6403 6414
- (2007) FEBS J. , vol.274 , pp. 6403-6414
- Egeblad-Welin, L.¹ Welin, M.² Wang, L.³ Eriksson, S.⁴

22
- 23844434045
- K.A. Kantardjieff, C. Vasquez, P. Castro, N.M. Warfel, B.S. Rho, T. Lekin, C.Y. Kim, B.W. Segelke, T.C. Terwilliger, and B. Rupp Acta Crystallogr. D: Biol. Crystallogr. 61 2005 355 364
- (2005) Acta Crystallogr. D: Biol. Crystallogr. , vol.61 , pp. 355-364
- Kantardjieff, K.A.¹ Vasquez, C.² Castro, P.³ Warfel, N.M.⁴ Rho, B.S.⁵ Lekin, T.⁶ Kim, C.Y.⁷ Segelke, B.W.⁸ Terwilliger, T.C.⁹ Rupp, B.¹⁰

23
- 0032508046
- S.T. Cole, R. Brosch, J. Parkhill, T. Garnier, C. Churcher, D. Harris, S.V. Gordon, K. Eiglmeier, S. Gas, C.E. Barry, F. Tekaia, K. Badcock, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. Davies, K. Devlin, T. Feltwell, S. Gentles, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, A. Krogh, J. McLean, S. Moule, L. Murphy, K. Oliver, J. Osborne, M.A. Quail, M.A. Rajandream, J. Rogers, S. Rutter, K. Seeger, J. Skelton, R. Squares, S. Squares, J.E. Sulston, K. Taylor, S. Whitehead, and B.G. Barrell Nature 393 1998 537 544
- (1998) Nature , vol.393 , pp. 537-544
- Cole, S.T.¹ Brosch, R.² Parkhill, J.³ Garnier, T.⁴ Churcher, C.⁵ Harris, D.⁶ Gordon, S.V.⁷ Eiglmeier, K.⁸ Gas, S.⁹ Barry, C.E.¹⁰ Tekaia, F.¹¹ Badcock, K.¹² Basham, D.¹³ Brown, D.¹⁴ Chillingworth, T.¹⁵ Connor, R.¹⁶ Davies, R.¹⁷ Devlin, K.¹⁸ Feltwell, T.¹⁹ Gentles, S.²⁰ more..

24
- 34548239766
- D. Robertson, P. Carroll, and T. Parish Tuberculosis 87 2007 450 458
- (2007) Tuberculosis , vol.87 , pp. 450-458
- Robertson, D.¹ Carroll, P.² Parish, T.³

25
- 0026485123
- K. Yamanaka, T. Ogura, H. Niki, and S. Hiraga J. Bacteriol. 174 1992 7517 7526
- (1992) J. Bacteriol. , vol.174 , pp. 7517-7526
- Yamanaka, K.¹ Ogura, T.² Niki, H.³ Hiraga, S.⁴

26
- 0011106749
- J.C. Smallshaw, and R.A. Kelln Genetics (Life Sci. Adv.) 11 1992 59 65
- (1992) Genetics (Life Sci. Adv.) , vol.11 , pp. 59-65
- Smallshaw, J.C.¹ Kelln, R.A.²

27
- 0004136246
- Spring Harbor Laboratory Press New York
- J. Sambrook, and D.W. Russel Molecular Cloning: A Laboratory Manual 2001 Spring Harbor Laboratory Press New York
- (2001) Molecular Cloning: A Laboratory Manual
- Sambrook, J.¹ Russel, D.W.²

28
- 0014949207
- U.K. Laemmli Nature 227 1970 680 685
- (1970) Nature , vol.227 , pp. 680-685
- Laemmli, U.K.¹

29
- 0017184389
- M.M. Bradford Anal. Biochem. 72 1976 248 254
- (1976) Anal. Biochem. , vol.72 , pp. 248-254
- Bradford, M.M.¹

30
- 56149088837
- B. Monson de Souza, and M.S. Palma Biochim. Biophys. Acta 1778 2008 2797 2805
- (2008) Biochim. Biophys. Acta , vol.1778 , pp. 2797-2805
- Monson De Souza, B.¹ Palma, M.S.²

31
- 0031759474
- H. Chassaigne, and R. Lobinski Analyst 123 1998 2125 2130
- (1998) Analyst , vol.123 , pp. 2125-2130
- Chassaigne, H.¹ Lobinski, R.²

32
- 58149185141
- D.A. Benson, I. Karsch-Mizrachi, D.J. Lipman, J. Ostell, and E.W. Sayers Nucleic Acids Res. 37 2009 D26 D31
- (2009) Nucleic Acids Res. , vol.37
- Benson, D.A.¹ Karsch-Mizrachi, I.² Lipman, D.J.³ Ostell, J.⁴ Sayers, E.W.⁵

33
- 0027968068
- J.D. Thompson, D.G. Higgins, and T.J. Gibson Nucleic Acids Res. 22 1994 4673 4680
- (1994) Nucleic Acids Res. , vol.22 , pp. 4673-4680
- Thompson, J.D.¹ Higgins, D.G.² Gibson, T.J.³

34
- 0034889953
- J.S. Oliveira, C.A. Pinto, L.A. Basso, and D.S. Santos Protein Expr. Purif. 22 2001 430 435
- (2001) Protein Expr. Purif. , vol.22 , pp. 430-435
- Oliveira, J.S.¹ Pinto, C.A.² Basso, L.A.³ Santos, D.S.⁴

35
- 0003760238
- John Wiley and Sons New York
- I. Segel Enzyme Kinetics, Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems 1975 John Wiley and Sons New York
- (1975) Enzyme Kinetics, Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems
- Segel, I.¹

36
- 23944514165
- John Wiley and Sons, Inc. New Jersey
- R.A. Copeland Evaluation of Enzyme Inhibitors in Drug Discovery 2005 John Wiley and Sons, Inc. New Jersey
- (2005) Evaluation of Enzyme Inhibitors in Drug Discovery
- Copeland, R.A.¹

37
- 33947473184
- R.G. Bates, and H.B. Hetzer J. Phys. Chem. 65 1961 667 671
- (1961) J. Phys. Chem. , vol.65 , pp. 667-671
- Bates, R.G.¹ Hetzer, H.B.²

38
- 0031670461
- H. Fukada, and K. Takahashi Proteins 33 1998 159 166
- (1998) Proteins , vol.33 , pp. 159-166
- Fukada, H.¹ Takahashi, K.²

39
- 17144395537
- M.C. Pinna, A. Salis, M. Monduzzi, and B.W. Ninham J. Phys. Chem. B 109 2005 5406 5408
- (2005) J. Phys. Chem. B , vol.109 , pp. 5406-5408
- Pinna, M.C.¹ Salis, A.² Monduzzi, M.³ Ninham, B.W.⁴

40
- 33751408436
- Y. Zhang, and P.S. Cremer Curr. Opin. Chem. Biol. 10 2006 658 663
- (2006) Curr. Opin. Chem. Biol. , vol.10 , pp. 658-663
- Zhang, Y.¹ Cremer, P.S.²

41
- 58149088061
- P. Meyer, C. Evrin, P. Briozzo, N. Joly, O. Bârzu, and A. Gilles J. Biol. Chem. 283 2008 36011 36018
- (2008) J. Biol. Chem. , vol.283 , pp. 36011-36018
- Meyer, P.¹ Evrin, C.² Briozzo, P.³ Joly, N.⁴ Bârzu, O.⁵ Gilles, A.⁶

42
- 15844416304
- L. Serina, N. Bucurenci, A.M. Gilles, W.K. Surewicz, H. Fabian, H.H. Mantsch, M. Takahashi, I. Petrescu, G. Batelier, and O. Bârzu Biochemistry 35 1996 7003 7011
- (1996) Biochemistry , vol.35 , pp. 7003-7011
- Serina, L.¹ Bucurenci, N.² Gilles, A.M.³ Surewicz, W.K.⁴ Fabian, H.⁵ Mantsch, H.H.⁶ Takahashi, M.⁷ Petrescu, I.⁸ Batelier, G.⁹ Bârzu, O.¹⁰

43
- 34147149525
- C. Evrin, M. Straut, N. Slavova-Azmanova, N. Bucurenci, A. Onu, L. Assairi, M. Ionescu, N. Palibroda, O. Bârzu, and A. Gilles J. Biol. Chem. 282 2007 7242 7253
- (2007) J. Biol. Chem. , vol.282 , pp. 7242-7253
- Evrin, C.¹ Straut, M.² Slavova-Azmanova, N.³ Bucurenci, N.⁴ Onu, A.⁵ Assairi, L.⁶ Ionescu, M.⁷ Palibroda, N.⁸ Bârzu, O.⁹ Gilles, A.¹⁰

44
- 34249876230
- S.E. Lee, S.Y. Kim, C.M. Kim, M. Kim, Y.R. Kim, K. Jeong, H. Ryu, Y.S. Lee, S.S. Chung, H.E. Choy, and J.H. Rhee Infect. Immun. 75 2007 2795 2801
- (2007) Infect. Immun. , vol.75 , pp. 2795-2801
- Lee, S.E.¹ Kim, S.Y.² Kim, C.M.³ Kim, M.⁴ Kim, Y.R.⁵ Jeong, K.⁶ Ryu, H.⁷ Lee, Y.S.⁸ Chung, S.S.⁹ Choy, H.E.¹⁰ Rhee, J.H.¹¹

45
- 65249143233
- C. Thum, C.Z. Schneider, M.S. Palma, D.S. Santos, and L.A. Basso J. Bacteriol. 191 2009 2884 2887
- (2009) J. Bacteriol. , vol.191 , pp. 2884-2887
- Thum, C.¹ Schneider, C.Z.² Palma, M.S.³ Santos, D.S.⁴ Basso, L.A.⁵

46
- 13344275165
- N. Bucurenci, H. Sakamoto, P. Briozzo, N. Palibroda, L. Serina, R.S. Sarfati, G. Labesse, G. Briand, A. Danchin, O. Brzu, and A.M. Gilles J. Biol. Chem. 271 1996 2856 2862
- (1996) J. Biol. Chem. , vol.271 , pp. 2856-2862
- Bucurenci, N.¹ Sakamoto, H.² Briozzo, P.³ Palibroda, N.⁴ Serina, L.⁵ Sarfati, R.S.⁶ Labesse, G.⁷ Briand, G.⁸ Danchin, A.⁹ Brzu, O.¹⁰ Gilles, A.M.¹¹

47
- 78651189765
- J. Monod, J. Wyman, and J.P. Changeux J. Mol. Biol. 12 1965 88 118
- (1965) J. Mol. Biol. , vol.12 , pp. 88-118
- Monod, J.¹ Wyman, J.² Changeux, J.P.³

48
- 54349105873
- T.S. Balganesh, P.M. Alzari, and S.T. Cole Trends Pharmacol. Sci. 29 2008 576 581
- (2008) Trends Pharmacol. Sci. , vol.29 , pp. 576-581
- Balganesh, T.S.¹ Alzari, P.M.² Cole, S.T.³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.