13915*G DNA polymorphism associated with lactase persistence in Africa interacts with Oct-1

Human Genetics

Volumn 129, Issue 1, 2011, Pages 111-113

  Olds, Lynne C ^a   Ahn, Jong Kun ^b   Sibley, Eric ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b Korea National Open University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

LACTASE; OCTAMER TRANSCRIPTION FACTOR 1; LACTOSE;

AFRICA; AGING; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CELL CULTURE; CORRELATION ANALYSIS; DNA POLYMORPHISM; DNA SEQUENCE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE INTERACTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION; SINGLE NUCLEOTIDE POLYMORPHISM; GENE EXPRESSION REGULATION; GENETIC EPISTASIS; GENETICS; LACTOSE INTOLERANCE; METABOLISM; NUCLEOTIDE SEQUENCE;

AFRICA; BASE SEQUENCE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EPISTASIS, GENETIC; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LACTASE; LACTOSE; LACTOSE INTOLERANCE; OCTAMER TRANSCRIPTION FACTOR-1; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC;

EID: 78651240254     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-010-0898-0     Document Type: Article

References (8)

1. NS Enattah T Sahi E Savilahti JD Terwilliger L Peltonen I Jarvela 2002 Identification of a variant associated with adult-type hypolactasia Nat Genet 30 2 233 237 1:CAS:528:DC%2BD38XhtFWltbw%3D 10.1038/ng826 11788828
2. NS Enattah TG Jensen M Nielsen R Lewinski M Kuokkanen H Rasinpera H El-Shanti JK Seo M Alifrangis IF Khalil A Natah A Ali S Natah D Comas SQ Mehdi L Groop EM Vestergaard F Imtiaz MS Rashed B Meyer J Troelsen L Peltonen 2008 Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture Am J Hum Genet 82 1 57 72 1:CAS:528:DC%2BD1cXhsFOks70%3D 10.1016/j.ajhg.2007.09.012 18179885 (Pubitemid 351735951)
3. HP Hauri B Sander H Naim 1994 Induction of lactase biosynthesis in the human intestinal epithelial cell line caco-2 Eur J Biochem 219 1-2 539 546 1:CAS:528:DyaK2cXhtlSku7c%3D 10.1111/j.1432-1033.1994.tb19969.x 7508390
4. CJ Ingram MF Elamin CA Mulcare ME Weale A Tarekegn TO Raga E Bekele FM Elamin MG Thomas N Bradman DM Swallow 2007 A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence? Hum Genet 120 6 779 788 1:CAS:528:DC%2BD2sXnsF2hsg%3D%3D 10.1007/s00439-006-0291-1 17120047 (Pubitemid 46128833)
5. RH Lewinsky TG Jensen J Moller A Stensballe J Olsen JT Troelsen 2005 T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro Hum Mol Genet 14 24 3945 3953 1:CAS:528:DC%2BD2MXhtlChsrrN 10.1093/hmg/ddi418 16301215 (Pubitemid 43020095)
6. LC Olds E Sibley 2003 Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element Hum Mol Genet 12 18 2333 2340 1:CAS:528:DC%2BD3sXntVCru7s%3D 10.1093/hmg/ddg244 12915462 (Pubitemid 37160877)
7. SA Tishkoff FA Reed A Ranciaro BF Voight CC Babbitt JS Silverman K Powell HM Mortensen JB Hirbo M Osman M Ibrahim SA Omar G Lema TB Nyambo J Ghori S Bumpstead JK Pritchard GA Wray P Deloukas 2007 Convergent adaptation of human lactase persistence in Africa and Europe Nat Genet 39 1 31 40 1:CAS:528:DC%2BD28XhtlGktLjK 10.1038/ng1946 17159977 (Pubitemid 46026499)
8. JT Troelsen J Olsen J Moller H Sjostrom 2003 An upstream polymorphism associated with lactase persistence has increased enhancer activity Gastroenterology 125 6 1686 1694 1:CAS:528:DC%2BD2cXhtVOrtw%3D%3D 10.1053/j.gastro.2003.09.031 14724821 (Pubitemid 37500433)