Insulin-resistant brain state (IRBS) changes membrane composition of fatty acids in temporal and entorhinal brain cortices of rats: Relevance to sporadic Alzheimer's disease?

Journal of Neural Transmission

Volumn 117, Issue 12, 2010, Pages 1419-1422

  Plaschke, Konstanze ^b   Müller, Dorothea ^a   Hoyer, Siegfried ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b NONE

Author keywords

Fatty acid; Insulin; IRBS; Sporadic Alzheimer's disease

Indexed keywords

ARACHIDONIC ACID; MEMBRANE PHOSPHOLIPID; OLEIC ACID; PALMITIC ACID; STEARIC ACID;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN MEMBRANE; CONTROLLED STUDY; ENTORHINAL CORTEX; FRONTAL CORTEX; INSULIN RESISTANCE; LIPID COMPOSITION; MALE; MEMBRANE STRUCTURE; NONHUMAN; PRIORITY JOURNAL; RAT; SPORADIC ALZHEIMER DISEASE; STREPTOZOCIN DIABETES; TEMPORAL CORTEX;

ALZHEIMER DISEASE; ANIMALS; DIABETES COMPLICATIONS; ENTORHINAL CORTEX; FATTY ACIDS; INSULIN RESISTANCE; MALE; MEMBRANE LIPIDS; RATS; RATS, WISTAR; TEMPORAL LOBE; TIME;

EID: 78651230721     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-010-0523-3     Document Type: Article

References (27)

1. K Abe T Araki M Aoki K Kogure 1992 Phospholipid metabolism and second messenger system after brain ischemia Adv Exp Med Biol 318 183 195 1:CAS:528:DyaK3sXnvVGgtg%3D%3D 1636489
2. O Blondel B Portha 1989 Early appearance of in vivo insulin resistance in adult streptozotocin-injected rats Diabete Metab 15 382 387 1:CAS:528:DyaK3MXkt1Oh 2697607
3. H Braak E Braak 1991 Neuropathological stageing of Alzheimer-related changes Acta Neuropathol 82 239 259 1:STN:280:DyaK387gtFOiug%3D%3D 1759558
4. A Ding R Nitsch S Hoyer 1992 Changes in brain monoaminergic neurotransmitter concentrations in rat after intracerebroventricular injection of streptozotocin J Cereb Blood Flow Metab 12 103 109 1:CAS:528: DyaK38Xht1KhsL8%3D 1370067
5. E Grünblatt M Salkovic-Petrisic J Osmanovic P Riederer S Hoyer 2007 Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein J Neurochem 101 757 770 17448147
6. R Hellweg R Nitsch C Hock M Jaksch S Hoyer 1992 Nerve growth factor and choline acetyltransferase activity levels in the rat brain following experimental impairment of cerebral glucose and energy metabolism J Neurosci Res 31 479 486 1:CAS:528:DyaK38XitFahurk%3D 1386388
7. F Hirata J Axelrod 1980 Phospholipid methylation and biological signal transmission Science 209 1082 1090 1:CAS:528:DyaL3cXlvVeiu7c%3D 6157192
8. S Hoyer 1992 The biology of the aging brain, oxidative and related metabolism Eur J Gerontol 1 157 165
9. BT Hyman GW Van Hoesen AR Damasio CL Barnes 1984 Alzheimer's disease: cell-specific pathology isolates the hippocampal formation Science 225 1168 1170 1:STN:280:DyaL2czgtVejsg%3D%3D 6474172
10. I Kadish O Thibault EM Blalock KC Chen JC Gant NM Porter PW Landfield 2009 Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment J Neurosci 29 1805 1816 1:CAS:528:DC%2BD1MXit1Witbk%3D 19211887
11. T Kadowaki M Kasuga Y Akanuma O Ezaki F Takaku 1984 Decreased autophosphorylation of the insulin receptor-kinase in streptozotocin-diabetic rats J Biol Chem 259 14208 14216 1:CAS:528:DyaL2cXmtVylsr0%3D 6389544
12. H Lannert S Hoyer 1998 Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats Behav Neurosci 112 1199 1208 1:CAS:528:DyaK1cXnsleis7g%3D 9829797 (Pubitemid 28519002)
13. D Müller RM Nitsch RJ Wurtman S Hoyer 1998 Streptozotocin increases free fatty acids and decreases phospholipids in rat brain J Neural Transm 105 1271 1281 9928896
14. R Nitsch S Hoyer 1991 Local action of the diabetogenic drug, streptozotocin, on glucose and energy metabolism in rat brain cortex Neurosci Lett 128 199 202 1:CAS:528:DyaK3MXltlehs7c%3D 1834965
15. RM Nitsch JK Blusztajn AG Pittas BE Slack JH Growdon RJ Wurtman 1992 Evidence for a membrane defect in Alzheimer disease brain Proc Natl Acad Sci USA 89 1671 1675 1:CAS:528:DyaK38XhslWmsLY%3D 1311847
16. K Plaschke S Hoyer 1993 Action of the diabetogenic drug streptozotocin on glycolytic and glycogenolytic metabolism in adult rat brain cortex and hippocampus Int J Dev Neurosci 11 477 483 1:CAS:528:DyaK2cXhs1Slt7g%3D 8237464
17. D Praticò K Uryu S Leight JQ Trojanoswki VM Lee 2001 Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis J Neurosci 21 4183 4187 11404403
18. WB Rowe EM Blalock KC Chen I Kadish D Wang JE Barrett O Thibault NM Porter GM Rose PW Landfield 2007 Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats J Neurosci 27 3098 3110 1:CAS:528:DC%2BD2sXktlKnsL0%3D 17376971
19. M Salkovic-Petrisic S Hoyer 2007 Central insulin resistance as a trigger for sporadic Alzheimer-like pathology: an experimental approach J Neural Transm Suppl 72 217 233 1:CAS:528:DC%2BD2sXhsVKns7bN 17982898
20. M Salkovic-Petrisic F Tribl M Schmidt S Hoyer P Riederer 2006 Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway J Neurochem 96 1005 1015 1:CAS:528:DC%2BD28XivFWjsr8%3D 16412093
21. M Salkovic-Petrisic J Osmanovic E Grünblatt P Riederer S Hoyer 2009 Modeling sporadic Alzheimer's disease: the insulin resistant brain state generates multiple long-term morphobiological abnormalities including hyperphosphorylated tau protein and amyloid-beta J Alzheimers Dis 18 729 750 1:CAS:528:DC%2BD1MXhsFynsrnK 19661616
22. AA Spector MA Yorek 1985 Membrane lipid composition and cellular function J Lipid Res 26 1015 1035 1:CAS:528:DyaL2MXlsFOqsr0%3D 3906008
23. FF Sun WE Fleming BM Taylor 1993 Degradation of membrane phospholipids in the cultured human astroglial cell line UC-11MG during ATP depletion Biochem Pharmacol 45 1149 1155 1:CAS:528:DyaK3sXksVSksL0%3D 8461044
24. J Svedberg P Björntorp U Smith P Lönnroth 1990 Free-fatty acid inhibition of insulin binding, degradation, and action in isolated rat hepatocytes Diabetes 39 570 574 1:CAS:528:DyaK3cXktVSrsbw%3D 2185108
25. Y Wu FF Sun DM Tong BM Taylor 1996 Changes in membrane properties during energy depletion-induced cell injury studied with fluorescence microscopy Biophys J 71 91 100 1:CAS:528:DyaK28XktVOhu7c%3D 8804592
26. JK Yao TM Wengenack GL Curran JF Poduslo 2009 Reduced membrane lipids in the cortex of Alzheimer's disease transgenic mice Neurochem Res 34 102 108 1:CAS:528:DC%2BD1MXktValsQ%3D%3D 18373196
27. AW Yuen JW Sander D Fluegel PN Patsalos GS Bell T Johnson MJ Koepp 2005 Omega-3 fatty acid supplementation in patients with chronic epilepsy: a randomized trial Epilepsy Behav 7 253 258 16006194