Synthesis of the sphingolipid activator protein, saposin C, using an azido-protected O-acyl isopeptide as an aggregation-disrupting element

Tetrahedron Letters

Volumn 52, Issue 5, 2011, Pages 635-639

  Hojo, Hironobu ^a   Katayama, Hidekazu ^a   Tano, Chiharu ^a   Nakahara, Yuko ^a   Yoneshige, Azusa ^a   Matsuda, Junko ^a   Sohma, Youhei ^b   Kiso, Yoshiaki ^b   Nakahara, Yoshiaki ^a  

^a TOKAI UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Azido group; Native chemical ligation; O Acyl isopeptide; Peptide thioester; Saposin C

Indexed keywords

AZIDE; GLYCOSPHINGOLIPID; PEPTIDE; SAPOSIN C; SPHINGOLIPID ACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; CARBOXY TERMINAL SEQUENCE; DISULFIDE BOND; PROTEIN AGGREGATION; PROTEIN SYNTHESIS; SOLID PHASE SYNTHESIS; SOLUBILITY;

EID: 78651113484     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.11.154     Document Type: Article

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