Target vessel reopening by guidewire insertion in ST-elevation myocardial infarction is a predictor of final TIMI flow and survival

Thrombosis and Haemostasis

Volumn 105, Issue 1, 2011, Pages 52-58

  Adlbrecht, Christopher ^a   Distelmaier, Klaus ^a   Gündüz, Duygu ^a   Redwan, Bassam ^a   Plass, Christian ^a   Bonderman, Diana ^a   Kaider, Alexandra ^a   Christ, Günter ^a   Lang, Irene M ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Guidewire; Myocardial infarction; Prognosis; Reperfusion; Thrombectomy

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; FIBRINOGEN RECEPTOR ANTAGONIST; GLYCERYL TRINITRATE; HEPARIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ADULT; ANGIOCARDIOGRAPHY; ARTICLE; CONFIDENCE INTERVAL; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; CORONARY ARTERY THROMBOSIS; ECHOCARDIOGRAPHY; FEMALE; GUIDE WIRE; HAZARD RATIO; HEART INFARCTION; HEART MUSCLE REPERFUSION; HUMAN; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PERCUTANEOUS CORONARY INTERVENTION; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; REGRESSION ANALYSIS; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; SURVIVAL; THROMBECTOMY; TREATMENT OUTCOME; UNIVARIATE ANALYSIS;

AGED; ANGIOPLASTY; CORONARY CIRCULATION; CORONARY VESSELS; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; MYOCARDIAL REVASCULARIZATION; PROGNOSIS; REGIONAL BLOOD FLOW; SURVIVAL RATE; THROMBOLYTIC THERAPY; TREATMENT OUTCOME;

EID: 78651110794     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH10-04-0246     Document Type: Article

References (26)

1. Thatcher JL, et al. Improved efficiency in acute myocardial infarction care through commitment to emergency department-initiated primary PCI. J Invasive Cardiol 2003; 15: 693-698.
2. Van de Werf F, et al. Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology. Eur Heart J 2008; 29: 2909-2945.
3. Gibson CM, et al. Relationship of the TIMI myocardial perfusion grades, flow grades, frame count, and percutaneous coronary intervention to long-term outcomes after thrombolytic administration in acute myocardial infarction. Circulation 2002; 105: 1909-1913.
4. Sabatine MS, et al. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med 2005; 352: 1179-1189.
5. Brodie BR, et al. Benefit of coronary reperfusion before intervention on outcomes after primary angioplasty for acute myocardial infarction. Am J Cardiol 2000; 85: 13-18.
6. van 't Hof AW, et al. Facilitation of primary coronary angioplasty by early start of a glycoprotein 2b/3a inhibitor: results of the ongoing tirofiban in myocardial infarction evaluation (On-TIME) trial. Eur Heart J 2004; 25: 837-846.
7. Kurowski V, et al. The effects of facilitated primary PCI by guide wire on procedural and clinical outcomes in acute ST-segment elevation myocardial infarction. Clin Res Cardiol 2007; 96: 557-565.
8. Chesebro JH, et al. Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge. Circulation 1987; 76: 142-154.
9. Kaplan E, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958; 53: 457-481
10. Cox D. Regression models and life tables. JR Stat Soc B 1972; 34: 187-220.
11. Lev EI, et al. Effect of clopidogrel pretreatment on angiographic and clinical outcomes in patients undergoing primary percutaneous coronary intervention for ST-elevation acute myocardial infarction. Am J Cardiol 2008; 101: 435-439.
12. Adlbrecht C, et al. Active endothelin is an important vasoconstrictor in acute coronary thrombi. Thromb Haemost 2007; 97: 642-649. (Pubitemid 46592943)
13. Distelmaier K, et al. Local complement activation triggers neutrophil recruitment to the site of thrombus formation in acute myocardial infarction. Thromb Haemost 2009; 102: 564-572.
14. Perrin J, et al. In vitro effects of human neutrophil cathepsin G on thrombin generation: Both acceleration and decreased potential. Thromb Haemost 2010; 104: 514-522.
15. Bonderman D, et al. Role for staphylococci in misguided thrombus resolution of chronic thromboembolic pulmonary hypertension. Arterioscl Thromb Vasc Biol 2008; 28: 678-684. (Pubitemid 351651329)
16. Bernlochner I, et al. Association between inflammatory biomarkers and platelet aggregation in patients under chronic clopidogrel treatment. Thromb Haemost 2010; 104: 1193-1200.
17. Kramer MC, et al. Presence of older thrombus is an independent predictor of long-term mortality in patients with ST-elevation myocardial infarction treated with thrombus aspiration during primary percutaneous coronary intervention. Circulation 2008; 118: 1810-1816.
18. Hausenloy DJ. Signalling pathways in ischaemic postconditioning. Thromb Haemost 2009; 101: 626-634.
19. Stone GW, et al. Normal flow (TIMI-3) before mechanical reperfusion therapy is an independent determinant of survival in acute myocardial infarction: analysis from the primary angioplasty in myocardial infarction trials. Circulation 2001; 104: 636-641.
20. De Luca G, et al. Symptom-onset-to-balloon time and mortality in patients with acute myocardial infarction treated by primary angioplasty. J Am Coll Cardiol 2003; 42: 991-997. (Pubitemid 37108581)
21. Bates E, et al. Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction. Circulation 2008; 117: 886-896.
22. Nakatani D, et al. Effect of intracoronary thrombectomy on 30-day mortality in patients with acute myocardial infarction. Am J Cardiol 2007; 100: 1212-1217.
23. Maioli M, et al. Randomized early versus late abciximab in acute myocardial infarction treated with primary coronary intervention (RELAx-AMI Trial). J Am Coll Cardiol 2007; 49: 1517-1524.
24. Ellis SG, et al. Facilitated PCI in patients with ST-elevation myocardial infarction. N Engl J Med 2008; 358: 2205-2217.
25. Cannon CP. Importance of TIMI 3 flow. Circulation 2001; 104: 624-626.
26. Beran G, et al. Intracoronary thrombectomy with the X-sizer catheter system improves epicardial flow and accelerates ST-segment resolution in patients with acute coronary syndrome: a prospective, randomized, controlled study. Circulation 2002; 105: 2355-2360.