TNF microsatellite alleles may confer protection against the development of lipodystrophy syndrome in Brazilian HIV patients

International Journal of Immunogenetics

Volumn 37, Issue 5, 2010, Pages 379-385

  Silva, M M ^a   Simoes R T ^a   Castelli, E C ^a   Mendes Junior, C T ^a   Deghaide, N H S ^a   Tsuda, L C ^a   Machado, A A ^a   Donadi, E A ^a   Fernandes, A P M ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA5; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ALLELE; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE PREDISPOSITION; GENE AMPLIFICATION; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV ASSOCIATED LIPODYSTROPHY; HOMOZYGOSITY; HOMOZYGOTE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION;

ADULT; ALLELES; BRAZIL; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HIV INFECTIONS; HIV-ASSOCIATED LIPODYSTROPHY SYNDROME; HUMANS; MICROSATELLITE REPEATS; MIDDLE AGED; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78651103879     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/j.1744-313X.2010.00937.x     Document Type: Article

References (35)

1. van Belle, G., Fisher, L.D., Heagerty, P.J. & Lumley, T.S. (2004). Biostatistics: A Methodology for the Health Sciences, 2nd edn. John Wiley & Sons, Inc., Hoboken, NJ.
2. Bouma, G., Xia, B., Crusius, J.B., Bioque, G., Koutroubakis, I., Von Blomberg, B.M. et al. (1996) Distribution of four polymorphism in the tumour necrosis factor (TNF) genes in patients with inflammatory bowel disease (IBD). Clinical Experiments in Immunology, 103, 391.
3. Christeff, N., Melchior, J.C., de Trchis, P., Perronne, C., Nunez, E.A. & Gougeon, M.L. (1999) Lipodystrophy defined by a clinical score in HIV-infected men on highly active antiretroviral therapy: correlation between dyslipidaemia and steroid hormone alterations. AIDS, 13, 2251.
4. D'Alfonso, S. & Richiardi, P.M. (1994) A polymorphic variation in a putative regulation box of the TNFA promoter region. Immunogenetics, 39, 150.
5. Danis, V.A., Millington, M., Hyland, V., Lawford, R., Huang, Q. & Grennan, D. (1995) Increased frequency of the uncommon allele of a tumour necrosis factor alpha gene polymorphism in rheumatoid arthritis and systemic lupus erythematous. Disease Markers, 12, 127.
6. Derky, H.H., Bruin, K.F. & Jongeneel, C.V. (1995) Familial differences in endotoxin-induced TNF release in whole blood and pheriferal blood mononuclear cells in vitro: relationship to TNF gene polymorphism. Journal of Endothelial Research, 2, 19.
7. Excoffier, L. & Slatkin, M. (1998) Incorporating genotypes of relatives into a test of linkage disequilibrium. American Journal of Human Genetics, 62, 171.
8. Excoffier, L., Laval, G. & Scheneider, S. (2005) Arlequin ver. 3.0: An integrated software package for population genetics data analysis. Evolution Bioinform Online, 1, 47.
9. Field, M. (2001) Tumour necrosis factor polymorphisms in rheumatic diseases. Quarterly Journal of Medicine, 94, 237.
10. Guo, S.W. & Thompson, E.A. (1992) Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics, 48, 361.
11. Huizinga, T.W., Westendorp, R.G., Bollen, E.L., Keijseres, V., Brinkman, B.M., Langermans, J.A. et al. (1997) TNF-alpha promoter polymorphisms, production and susceptibility to multiple sclerosis in different groups of patients. Journal of Neuroimmunology, 72, 149.
12. Johnson, J.A., Albu, J.B., Engelson, E.S., Fried, S.K., Inada, Y., Ionescu, G. et al. (2004) Increased systemic and adipose tissue cytokines in patients with HIV-associated lipodystrophy. American Journal of Physiology and Endocrinological Metabolism, 286, 261.
13. Kroeger, K.M., Carville, K.S. & Abraham, L.J. (1997) The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription. Molecular Immunology, 34, 391.
14. Ledru, E., Christeff, N., Patey, O., Melchior, J.C. & Gougeon, M.L. (2000) Alteration of tumor necrosis factor-alpha T-cell homeostasis following potent antiretroviral therapy: contribution to the development of human immunodeficiency virusassociated lipodystrophy syndrome. Blood, 95, 3191.
15. Lois, E., Franchimont, D., Piron, A., Gevaert, Y., Schaaf-Lafontaine, N., Roland, S. et al. (1998) Tumour necrosis factor (TNF) gene polymorphism influences TNF-alpha production in lipopolysaccharide (LPS)-stimulated whole blood cell culture in healthy humans. Clinical Experiments in Immunology, 113, 401.
16. Maher, B., Alfirevic, A., Vilar, F.J., Wilkins, E.G.L, Park, B.K. & Pirmohamed, M. (2002) TNF-α promoter region gene polymorphisms in HIV-positive patients with lipodystrophy. AIDS, 16, 2013.
17. Marsh, H.P., Haldar, N.A., Bunce, M., Marshall, S.E., Le Monier, K., Winsey, S.L. et al. (2003) Polymorphisms in tumour necrosis factor (TNF) are associated with risk of bladder cancer and grade of tumour at presentation. British Journal of Câncer, 89, 1096.
18. Miller, A.S., Dykes, D.D. & Polenky, H.F. (1988) A simple salting out procedure for extracting DNA for human nucleated cells. Nucleic Acids Research, 16, 1215.
19. Miller, J., Carr, A., Emery, S., Law, M., Malla, S., Baker, D. et al. (2003) HIV lipodystrophy: prevalence, severity and correlates of risk in Australia. HIV Médicine, 4, 293.
20. Mycko, M., Kowalski, W., Kwinkowski, M., Buenafe, A.C., Szymanska, B., Tronczynska, E. et al. (1998) Multiple sclerosis: the frequency of allelic forms of tumour necrosis factor and lymphotoxin-alpha. Journal of Neuroimmunology, 84, 198.
21. Nolan, D., Moore, C., Castley, A., Sayer, D., Mamotte, C., John, M. et al. (2003) Tumour necrosis factor-alpha gene -238G/A promoter polymorphism associated with a more rapid onset of lipodystrophy. AIDS, 17, 121.
22. Pociot, F., Briant, L., Jongeneel, C.V., Molving, J., Worsaae, H., Abbal, M. et al. (1993) Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-alpha and TNF-beta by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. European Journal of Immunology, 23, 224.
23. Raymond, M. & Rousset, F. (1995a) An exact test for population differentiation. Evolution, 49, 1280.
24. Raymond, M. & Rousset, F. (1995b) GENEPOP (version 1.2): population genetics software for exact tests and ecumenicism. Journal of Heredity, 86, 248.
25. Sanguinetti, C.J., Dias Neto, E. & Simpson, A.J. (1994) Rapid silver staining and recovery of PCR products separated on polyacrylamide gels. BioTechniques, 17, 914.
26. Stephens, M., Smith, N.J. & Donnelly, P. (2001) A new statistical method for haplotype reconstruction from population data. American Journal of Human Genetics, 68, 978.
27. Tarr, P.E., Taffé, P., Bleiber, G., Furrer, H., Rotger, M., Martinez, R. et al. (2005) HIV Cohort Study. Modeling the influence of APOC3, APOE, and TNF polymorphisms on the risk of antiretroviral therapy-associated lipid disorders. The Journal of Infectious Diseases, 191, 1419.
28. Tsukamoto, K., Ohta, N., Shiral, Y. & Emi, M. (1998) A highly polymorphic CA repeat marker at the human tumor necrosis factor alpha (TNFA alpha) locus. Journal of Human Genetics, 43, 278.
29. Tugular, S., Berthoux, P. & Berthoux, F. (2003) Polymorphisms of the tumour necrosis factor alpha gene at position -308 and TNFd microsatellite in primary IgA nephropathy. Nephrology and Dialectic Transplant, 18, 724.
30. Turner, D.M., Grants, S.C., Lamb, W.R., Brenchley, P.E., Dyer, P.A., Sinnott, P.J. et al. (1995) A genetic marker of high TNFalpha production in heart transplant recipients. Transplantation, 60, 1113.
31. Udalova, I.A., Nedospasov, S.A., Webb, G.C., Chaplin, D.D. & Turretskaya, R.L. (1993) Highly informative typing of the human TNF locus using six adjacent polymorphic markers. Genomic, 16, 180.
32. Vassalli, P. (1992) The pathophysiology of tumor necrosis factors. Annual Review of Immunology, 10, 411.
33. Vigouroux, C., Maachi, M., Nguyen, T.H., Coussieu, C., Gharakhanian, S., Funahashi, T. et al. (2003) Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy. AIDS, 17, 1503.
34. Wilson, A.G., Di Giovine, F.S, Blakemore, A.I. & Duff, G.W. (1992) Single base polymorphism in the human tumour necrosis factor alpha (TNF-α) gene detectable by NcoI restriction of PCR product. Human Molecular Genetics, 1, 353.
35. Wilson, A.G., Symon, J.A., McDowell, T.L., McDevitt, H.O. & Duff, G.W. (1997) Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activity. Proceedings of National Academic Sciences of USA, 94, 3195.