Lactobacillus strains differentially modulate cytokine production by hPBMC from pollen-allergic patients

FEMS Immunology and Medical Microbiology

Volumn 61, Issue 1, 2011, Pages 28-40

  Vissers, Yvonne M ^a   Snel, Johannes ^b   Zuurendonk, Peter F ^c   Kleerebezem, Michiel ^b   Wichers, Harry J ^a   Savelkoul, Huub F J ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b NIZO FOOD RESEARCH   (Netherlands)

^c FRIESLANDCAMPINA   (Netherlands)

Author keywords

Allergy; Immunomodulation; Lactic acid bacteria; PBMC; Pollinosis; Probiotics

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IMMUNOMODULATION; LACTOBACILLUS; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS FERMENTUM; LACTOBACILLUS PLANTARUM; PERIPHERAL BLOOD MONONUCLEAR CELL; POLLEN ALLERGY; PRIORITY JOURNAL; TH1 CELL; TH2 CELL;

ANTIGENS, PLANT; BETULA; CELL DEATH; CELL PROLIFERATION; CYTOKINES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; HYPERSENSITIVITY; IMMUNOMODULATION; LACTOBACILLUS; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; POACEAE; POLLEN; RHINITIS, ALLERGIC, SEASONAL;

EID: 78651102003     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2010.00741.x     Document Type: Article

References (58)

1. Akdis CA & Akdis M (2009) Mechanisms and treatment of allergic disease in the big picture of regulatory T cells. J Allergy Clin Immun 123: 735-746; quiz 747-8.
2. Bickert T, Trujillo-Vargas CM, Duechs M, Wohlleben G, Polte T, Hansen G, Oelschlaeger TA & Erb KJ (2009) Probiotic Escherichia coli Nissle 1917 suppresses allergen-induced Th2 responses in the airways. Int Arch Allergy Imm 149: 219-230.
3. Bohle B (2007) The impact of pollen-related food allergens on pollen allergy. Allergy 62: 3-10.
4. Borchers AT, Selmi C, Meyers FJ, Keen CL & Gershwin ME (2009) Probiotics and immunity. J Gastroenterol 44: 26-46.
5. Boyle RJ, Robins-Browne RM & Tang ML (2006) Probiotic use in clinical practice: what are the risks? Am J Clin Nutr 83: 1256-1264; quiz 1446-1447.
6. Cammarota M, De Rosa M, Stellavato A, Lamberti M, Marzaioli I & Giuliano M (2009) In vitro evaluation of Lactobacillus plantarum DSMZ 12028 as a probiotic: emphasis on innate immunity. Int J Food Microbiol 135: 90-98.
7. Chen T, Isomaki P, Rimpilainen M & Toivanen P (1999) Human cytokine responses induced by gram-positive cell walls of normal intestinal microbiota. Clin Exp Immunol 118: 261-267.
8. D'Amato G, Cecchi L, Bonini S, Nunes C, Annesi-Maesano I, Behrendt H, Liccardi G, Popov T & van Cauwenberge P (2007) Allergenic pollen and pollen allergy in Europe. Allergy 62: 976-990.
9. de Roock S, van Elk M, van Dijk MEA, Timmerman HM, Rijkers GT, Prakken BJ, Hoekstra MO & de Kleer IM (2010) Lactic acid bacteria differ in their ability to induce functional regulatory T cells in humans. Clin Exp Aller 40: 103-110.
10. Drouault-Holowacz S, Foligne B, Dennin V, Goudercourt D, Terpend K, Burckel A & Pot B (2006) Anti-inflammatory potential of the probiotic dietary supplement Lactibiane tolerance: in vitro and in vivo considerations. Clin Nutr 25: 994-1003.
11. Ebner C, Schenk S, Najafian N, Siemann U, Steiner R, Fischer GW, Hoffmann K, Szepfalusi Z, Scheiner O & Kraft D (1995) Nonallergic individuals recognize the same T cell epitopes of Bet v 1, the major birch pollen allergen, as atopic patients. J Immunol 154: 1932-1940.
12. Erkeller-Yuksel FM, Deneys V, Yuksel B et al. (1992) Age-related changes in human blood lymphocyte subpopulations. J Pediatr 120: 216-222.
13. Fink LN (2010) Induction of regulatory T cells by probiotics: potential for treatment of allergy? Clin Exp Allergy 40: 5-8.
14. Flinterman AE, Knol EF, van Ieperen-van Dijk AG, Timmerman HM, Knulst AC, Bruijnzeel-Koomen CA, Pasmans SG & van Hoffen E (2007) Probiotics have a different immunomodulatory potential in vitro versus ex vivo upon oral administration in children with food allergy. Int Arch Allergy Imm 143: 237-244.
15. Foligne B, Nutten S, Grangette C, Dennin V, Goudercourt D, Poiret S, Dewulf J, Brassart D, Mercenier A & Pot B (2007) Correlation between in vitro and in vivo immunomodulatory properties of lactic acid bacteria. World J Gastroentero 13: 236-243.
16. Gabrielsson S, Paulie S, Rak S, Lagging E, Van Hage-Hamsten M, Harfast B & Troye-Blomberg M (1997) Specific induction of interleukin-4-producing cells in response to in vitro allergen stimulation in atopic individuals. Clin Exp Allergy 27: 808-815.
17. Garn H & Renz H (2007) Epidemiological and immunological evidence for the hygiene hypothesis. Immunobiology 212: 441-452.
18. Ghadimi D, Fölster-Holst R, de Vrese M, Winkler P, Heller KJ & Schrezenmeir J (2008) Effects of probiotic bacteria and their genomic DNA on TH1/TH2-cytokine production by peripheral blood mononuclear cells (PBMCs) of healthy and allergic subjects. Immunobiology 213: 677-692.
19. Green DR, Droin N & Pinkoski M (2003) Activation-induced cell death in T cells. Immunol Rev 193: 70-81.
20. Haller D, Blum S, Bode C, Hammes WP & Schiffrin EJ (2000) Activation of human peripheral blood mononuclear cells by nonpathogenic bacteria in vitro: evidence of NK cells as primary targets. Infect Immun 68: 752-759.
21. Isolauri E & Salminen S (2008) Probiotics: use in allergic disorders: a Nutrition, Allergy, Mucosal Immunology, and Intestinal Microbiota (NAMI) Research Group Report. J Clin Gastroenterol 42 (suppl 2): S91-S96.
22. Isolauri E, Sutas Y, Kankaanpaa P, Arvilommi H & Salminen S (2001) Probiotics: effects on immunity. Am J Clin Nutr 73: 444S-450S.
23. Jentsch-Ullrich K, Koenigsmann M, Mohren M & Franke A (2005) Lymphocyte subsets' reference ranges in an age- and gender-balanced population of 100 healthy adults - a monocentric German study. Clin Immunol 116: 192-197.
24. Jeurink PV, Vissers YM, Rappard B & Savelkoul HF (2008) T cell responses in fresh and cryopreserved peripheral blood mononuclear cells: kinetics of cell viability, cellular subsets, proliferation, and cytokine production. Cryobiology 57: 91-103.
25. Kalliomaki M, Antoine JM, Herz U, Rijkers GT, Wells JM & Mercenier A (2010) Guidance for substantiating the evidence for beneficial effects of probiotics: prevention and management of allergic diseases by probiotics. J Nutr 140: 713S-721S.
26. Kankaanpaa P, Sutas Y, Salminen S & Isolauri E (2003) Homogenates derived from probiotic bacteria provide down-regulatory signals for peripheral blood mononuclear cells. Food Chem 83: 269-277.
27. Kim JY, Kwon JH, Ahn SH, Lee SI, Han YS, Choi YO, Lee SY, Ahn KM & Ji GE (2010) Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial. Pediatr Allergy Immu 21: e386-e93.
28. Kirjavainen PV & Gibson GR (1999) Healthy gut microflora and allergy: factors influencing development of the microbiota. Ann Med 31: 288-292.
29. Kleerebezem M, Hols P, Bernard E, Rolain T, Zhou M, Siezen RJ & Bron PA (2010) The extracellular biology of the lactobacilli. FEMS Microbiol Rev 34: 199-230.
30. Kwon HK, Lee CG, So JS, Chae CS, Hwang JS, Sahoo A, Nam JH, Rhee JH, Hwang KC & Im SH (2010) Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders. P Natl Acad Sci USA 107: 2159-2164.
31. Larche M (2007) Regulatory T cells in allergy and asthma. Chest 132: 1007-1014.
32. Lavasani S, Dzhambazov B, Nouri M, Fak F, Buske S, Molin G, Thorlacius H, Alenfall J, Jeppsson B & Westrom B (2010) A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells. PLoS One 5: e9009.
33. Lebeer S, Vanderleyden J & De Keersmaecker SC (2010) Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens. Nat Rev Microbiol 8: 171-184.
34. Li N, Russel WM, Douglas-escobar M, Hauser N, Lopez M & Neu J (2009) Live and heat-killed Lactobacillus rhamnosus GG: effects on proinflammatory and anti-inflammatory cytokines/chemokines in gastrostomy-fed infant rats. Pediatr Res 66: 203-207.
35. Lopez P, Gueimonde M, Margolles A & Suarez A (2010) Distinct Bifidobacterium strains drive different immune responses in vitro. Int J Food Microbiol 138: 157-165.
36. Majamaa H & Isolauri E (1997) Probiotics: a novel approach in the management of food allergy. J Allergy Clin Immun 99: 179-185.
37. Medina M, Izquierdo E, Ennahar S & Sanz Y (2007) Differential immunomodulatory properties of Bifidobacterium logum strains: relevance to probiotic selection and clinical applications. Clin Exp Immunol 150: 531-538.
38. Meijerink M, Van Hemert S, Taverne N, Wels M, de Vos P, Bron PA, Savelkoul HF, van Bilsen J, Kleerebezem M & Wells J (2010) Identification of genetic loci in Lactobacillus plantarum that modulate the immune response of dendritic cells using comparative genome hybridization. PLoS One 5: e10632.
39. Miettinen M, Vuopio-Varkila J & Varkila K (1996) Production of human tumor necrosis factor alpha, interleukin-6, and interleukin-10 is induced by lactic acid bacteria. Infect Immun 64: 5403-5405.
40. Miettinen M, Matikainen S, Vuopio-Varkila J, Pirhonen J, Varkila K, Kurimoto M & Julkunen I (1998) Lactobacilli and streptococci induce interleukin-12 (IL-12), IL-18, and gamma interferon production in human peripheral blood mononuclear cells. Infect Immun 66: 6058-6062.
41. Murch SH (2005) Probiotics as mainstream allergy therapy? Arch Dis Child 90: 881-882.
42. Niers LE, Timmerman HM, Rijkers GT, van Bleek GM, van Uden NO, Knol EF, Kapsenberg ML, Kimpen JL & Hoekstra MO (2005) Identification of strong interleukin-10 inducing lactic acid bacteria which down-regulate T helper type 2 cytokines. Clin Exp Allergy 35: 1481-1489.
43. Niers L, Martin R, Rijkers G, Sengers F, Timmerman H, van Uden N, Smidt H, Kimpen J & Hoekstra M (2009) The effects of selected probiotic strains on the development of eczema (the PandA study). Allergy 64: 1349-1358.
44. Ongol MP, Iguchi T, Tanaka M, Sone T, Ikeda H, Asano K & Nishimura T (2008) Potential of selected strains of lactic Acid bacteria to induce a Th1 immune profile. Biosci Biotech Bioch 72: 2847-2857.
45. Pessi T, Sutas Y, Hurme M & Isolauri E (2000) Interleukin-10 generation in atopic children following oral Lactobacillus rhamnosus GG. Clin Exp Allergy 30: 1804-1808.
46. Pineiro M & Stanton C (2007) Probiotic bacteria: legislative framework - requirements to evidence basis. J Nutr 137: 850S-853S.
47. Pochard P, Gosset P, Grangette C, Andre C, Tonnel AB, Pestel J & Mercenier A (2002) Lactic acid bacteria inhibit TH2 cytokine production by mononuclear cells from allergic patients. J Allergy Clin Immun 110: 617-623.
48. Rasche C, Wolfram C, Wahls M & Worm M (2007) Differential immunomodulating effects of inactivated probiotic bacteria on the allergic immune response. Acta Derm-Venereol 87: 305-311.
49. Rautava S, Kalliomaki M & Isolauri E (2005) New therapeutic strategy for combating the increasing burden of allergic disease: Probiotics-A Nutrition, Allergy, Mucosal Immunology and Intestinal Microbiota (NAMI) Research Group report. J Allergy Clin Immun 116: 31-37.
50. Romagnani S (2004) Immunologic influences on allergy and the TH1/TH2 balance. J Allergy Clin Immun 113: 395-400.
51. Savilahti E, Kuitunen M & Vaarala O (2008) Pre and probiotics in the prevention and treatment of food allergy. Curr Opin Allergy Clin Immunol 8: 243-248.
52. Shida K, Suzuki T, Kiyoshima-Shibata J, Shimada S & Nanno M (2006) Essential roles of monocytes in stimulating human peripheral blood mononuclear cells with Lactobacillus casei to produce cytokines and augment natural killer cell activity. Clin Vaccine Immunol 13: 997-1003.
53. Timmerman HM, Niers LE, Ridwan BU, Koning CJ, Mulder L, Akkermans LM, Rombouts FM & Rijkers GT (2007) Design of a multispecies probiotic mixture to prevent infectious complications in critically ill patients. Clin Nutr 26: 450-459.
54. Tracey KJ & Cerami A (1993) Tumor necrosis factor, other cytokines and disease. Annu Rev Cell Biol 9: 317-343.
55. van Baarlen P, Troost FJ, van Hemert S, van der Meer C, de Vos WM, de Groot PJ, Hooiveld GJ, Brummer RJ & Kleerebezem M (2009) Differential NF-kappaB pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance. P Natl Acad Sci USA 106: 2371-2376.
56. van Hoffen E, Korthagen NM, de Kivit S, Schouten B, Bardoel B, Duivelshof A, Knol J, Garssen J & Willemsen LE (2010) Exposure of intestinal epithelial cells to UV-killed Lactobacillus GG but not Bifidobacterium breve enhances the effector immune response in vitro. Int Arch Allergy Immunol 152: 159-168.
57. Vissers YM, Snel J, Zuurendonk PF, Smit BA, Wichers HJ & Savelkoul HF (2010) Differential effects of Lactobacillus acidophilus and Lactobacillus plantarum strains on cytokine induction in human peripheral blood mononuclear cells. FEMS Immunol Med Microbiol 59: 60-70.
58. Vliagoftis H, Kouranos VD, Betsi GI & Falagas ME (2008) Probiotics for the treatment of allergic rhinitis and asthma: systematic review of randomized controlled trials. Ann Allergy Asthma Immunol 101: 570-579.