Validated RP-LC-MS/MS method for the simultaneous determination of allopurinol and its major metabolite, oxypurinol, in human plasma

Journal of Liquid Chromatography and Related Technologies

Volumn 34, Issue 1, 2011, Pages 26-37

  Kasawar, Gajanan ^a   Razzak, Mushtaq ^a   Zaheer, Zahid ^b   Farooqui, Mazahar ^a  

^a MAULANA AZAD COLLEGE   (India)

^b Y B CHAVAN COLLEGE OF PHARMACY   (India)

Author keywords

allopurinol; human plasma; LC MS MS; oxypurinol; validation

Indexed keywords

ALLOPURINOL; HUMAN PLASMAS; LC-MS/MS; OXYPURINOL; VALIDATION;

ACETONITRILE; DRUG PRODUCTS; FORMIC ACID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METABOLITES; PLASMAS; RECOVERY;

PLASMA (HUMAN);

ACETONITRILE; ALLOPURINOL; FORMIC ACID; LAMIVUDINE; OXIPURINOL;

ANTICOAGULATION; ARTICLE; CORRELATION COEFFICIENT; DILUTION; DRUG DETERMINATION; DRUG STABILITY; FREEZE THAWING; HEMOLYSIS; HUMAN; LIMIT OF QUANTITATION; LINEAR REGRESSION ANALYSIS; MASS SPECTROMETRY; NEGATIVE ION ELECTROSPRAY; PLASMA; PRECIPITATION; QUALITY CONTROL; REVERSED PHASE LIQUID CHROMATOGRAPHY; STANDARD; STRUCTURE ACTIVITY RELATION;

EID: 78651095808     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2011.534692     Document Type: Article

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