Possible involvement of microRNAs (miR-135a*) in heart failure associated with 25bp deletion in MYBPC3 (cardiac myosin binding protein C) gene

Medical Hypotheses

Volumn 76, Issue 2, 2011, Pages 306-

  Uppugunduri, Chakradhara Rao Satyanarayana ^a  

^a JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 135A; MINERALOCORTICOID; MYOSIN BINDING PROTEIN C; UNCLASSIFIED DRUG;

BLOOD PRESSURE REGULATION; CARDIOMYOPATHY; EXON; GENE DELETION; HEART FAILURE; HEART HYPERTROPHY; HUMAN; HYPOTHESIS; INTRON; LETTER; MODULATION; PREDICTION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

CARDIOMYOPATHIES; CARRIER PROTEINS; EXONS; GENE DELETION; HEART FAILURE; HUMANS; INTRONS; MICRORNAS; MODELS, BIOLOGICAL;

EID: 78651091807     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2010.11.032     Document Type: Letter

References (10)

1. Ho Y.L., Wu C.C., Lin L.C., et al. Assessment of the coronary artery disease and systolic dysfunction in hypertensive patients with the dobutamine-atropine stress echocardiography: effect of the left ventricular hypertrophy. Cardiology 1998, 89:52-58.
2. Niimura H., Patton K.K., McKenna W.J., et al. Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly. Circulation 2002, 105:446-451.
3. Dhandapany P.S., Sadayappan S., Xue Y., et al. A common MYBPC3 (cardiac myosin binding protein C) variant associated with cardiomyopathies in South Asia. Nat Genet 2009, 41:187-191.
4. Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
5. Filipowicz W., Bhattacharyya S.N., Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?. Nat Rev Genet 2008, 9:102-114.
6. Griffiths-Jones S., Saini H.K., van Dongen S., Enright A.J. MiRBase: tools for microRNA genomics. Nucleic acid Res 2008, 36:D154-D158. (Database Issue).
7. Liu N., Olson E.N. MicroRNA regulatory networks in cardiovascular development. Dev Cell 2010, 18:510-525.
8. Ikeda S., Pu W.T. Expression and function of microRNAs in heart disease. Curr Drug Targets 2010, 11:913-925.
9. Sõber S., Laan M., Annilo T. MicroRNAs miR-124 and miR-135a are potential regulators of the mineralocorticoid receptor gene (NR3C2) expression. Biochem Biophys Res Commun 2010, 391:727-732.
10. Bruneau B.G. The developmental genetics of congenital heart disease. Nature 2008, 451:943-948.