Variably protease-sensitive prionopathy in a PRNP codon 129 heterozygous UK patient with co-existing tau, α synuclein and Aβ pathology

Acta Neuropathologica

Volumn 120, Issue 6, 2010, Pages 821-823

  Head, Mark W ^a   Lowrie, Suzanne ^a   Chohan, Gurjit ^a   Knight, Richard ^a   Scoones, David J ^b   Ironside, James W ^a,c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b JAMES COOK UNIVERSITY HOSPITAL   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Alzheimer's disease; Creutzfeldt Jakob disease; Lewy body disease; Prion protein; PRNP codon 129; Protease sensitive prionopathy

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID BETA PROTEIN; PRION PROTEIN; PROTEINASE; PROTEINASE K; TAU PROTEIN;

AGED; AMYLOID PLAQUE; CASE REPORT; CLINICAL FEATURE; CODON; DIFFUSE LEWY BODY DISEASE; ELECTROENCEPHALOGRAM; FATALITY; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; LETTER; MALE; MINI MENTAL STATE EXAMINATION; MUTISM; NEUROLOGIC DISEASE; NEUROPATHOLOGY; PRION DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CEREBROSPINAL FLUID LEVEL; TREMOR; UNITED KINGDOM; URINE INCONTINENCE; VASCULAR AMYLOIDOSIS; WALKING DIFFICULTY; WESTERN BLOTTING;

AGED; ALPHA-SYNUCLEIN; AMYLOID BETA-PEPTIDES; GREAT BRITAIN; HUMANS; MALE; MUTATION; PRION DISEASES; PRIONS; PROSPECTIVE STUDIES; TAU PROTEINS;

EID: 78651068014     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-010-0766-y     Document Type: Letter

References (6)

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