-
1
-
-
0023232216
-
Helsinki heart study: Primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia safety of treatment, changes in risk factors, and incidence of coronary heart disease
-
Frick MH, Elo O, Haapa K, Heinonen OP, Heinsalmi P, Helo P, Huttunen JK, Kaitaniemi P, Koskinen P, Manninen V (2003) Helsinki heart study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med 317:1237-1245
-
(2003)
N Engl J Med
, vol.317
, pp. 1237-1245
-
-
Frick, M.H.1
Elo, O.2
Haapa, K.3
Heinonen, O.P.4
Heinsalmi, P.5
Helo, P.6
Huttunen, J.K.7
Kaitaniemi, P.8
Koskinen, P.9
Manninen, V.10
-
2
-
-
0023726344
-
Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki heart study
-
Manninen V, Elo MO, Frick M, Haapa K, Heinonen OP, Heinsalm P, Helo P, Huttunen JK, Kaitaniem P, Koskinen P (1988) Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki heart study. JAMA 260:641-651
-
(1988)
JAMA
, vol.260
, pp. 641-651
-
-
Manninen, V.1
Elo, M.O.2
Frick, M.3
Haapa, K.4
Heinonen, O.P.5
Heinsalm, P.6
Helo, P.7
Huttunen, J.K.8
Kaitaniem, P.9
Koskinen, P.10
-
3
-
-
0017280786
-
Serum lipoproteins and coronary heart disease in a population study of Hawaii Japanese men
-
Rhoads GG, Gulbrandsen CL, Kagan A (1976) Serum lipoproteins and coronary heart disease in a population study of Hawaii Japanese men. N Engl J Med 294:293-298
-
(1976)
N Engl J Med
, vol.294
, pp. 293-298
-
-
Rhoads, G.G.1
Gulbrandsen, C.L.2
Kagan, A.3
-
4
-
-
0017384270
-
High density lipoprotein as a protective factor against coronary heart disease: The Framingham study
-
Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR (1977) High density lipoprotein as a protective factor against coronary heart disease: The Framingham study. Am J Med 66:707-714
-
(1977)
Am J Med
, vol.66
, pp. 707-714
-
-
Gordon, T.1
Castelli, W.P.2
Hjortland, M.C.3
Kannel, W.B.4
Dawber, T.R.5
-
5
-
-
0017614773
-
The Tromsø heart study: High-density lipoprotein and coronary heart-disease: A prospective case-control study
-
Miller NE, Thelle DS, Førde OH, Mjøs OD (1977) The Tromsø heart study: high-density lipoprotein and coronary heart-disease: A prospective case-control study. Lancet 1:964-968
-
(1977)
Lancet
, vol.1
, pp. 964-968
-
-
Miller, N.E.1
Thelle, D.S.2
Førde, O.H.3
Mjøs, O.D.4
-
6
-
-
0025014653
-
High density lipoprotein cholesterol as a predictor of cardiovascular disease mortality in men and women: The followup study of the lipid research clinics prevalence study
-
Jacobs DR Jr, Mebane IL, Bangdiwala SI, Criqu MH, Tyroler HA (1990) High density lipoprotein cholesterol as a predictor of cardiovascular disease mortality in men and women: The followup study of the lipid research clinics prevalence study. Am J Epidemiol 131:32-47
-
(1990)
Am J Epidemiol
, vol.131
, pp. 32-47
-
-
Jacobs Jr., D.R.1
Mebane, I.L.2
Bangdiwala, S.I.3
Criqu, M.H.4
Tyroler, H.A.5
-
7
-
-
36348975228
-
Effects of torcetrapib in patients at high risk for coronary events
-
Barter PJ, Caulfield M, Eriksson M, Grundy SM, Kastelein JJ, Komajda M, Lopez-Sendon J, Mosca L, Tardif JC, Waters DD, Shear CL, Revkin JH, Buhr KA, Fisher MR, Tall AR, Brewer HB (2007) Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med 357L:2109-2122
-
(2007)
N Engl J Med
, vol.357 L
, pp. 2109-2122
-
-
Barter, P.J.1
Caulfield, M.2
Eriksson, M.3
Grundy, S.M.4
Kastelein, J.J.5
Komajda, M.6
Lopez-Sendon, J.7
Mosca, L.8
Tardif, J.C.9
Waters, D.D.10
Shear, C.L.11
Revkin, J.H.12
Buhr, K.A.13
Fisher, M.R.14
Tall, A.R.15
Brewer, H.B.16
-
8
-
-
33745132444
-
Macrophage reverse cholesterol transport: Key to the regression of atherosclerosis?
-
Cuchel M, Rader DJ (2006) Macrophage reverse cholesterol transport: key to the regression of atherosclerosis? Circulation 113:2548-2555
-
(2006)
Circulation
, vol.113
, pp. 2548-2555
-
-
Cuchel, M.1
Rader, D.J.2
-
9
-
-
33646829831
-
Serum opacity factor, a streptococcal virulence factor that binds to apolipoproteins A-I and A-II and disrupts high density lipoprotein structure
-
Courtney HS, Zhang YM, Frank MW, Rock CO (2006) Serum opacity factor, a streptococcal virulence factor that binds to apolipoproteins A-I and A-II and disrupts high density lipoprotein structure. J Biol Chem 281:5515-5521
-
(2006)
J Biol Chem
, vol.281
, pp. 5515-5521
-
-
Courtney, H.S.1
Zhang, Y.M.2
Frank, M.W.3
Rock, C.O.4
-
10
-
-
36048999898
-
Serum opacity factor unmasks human plasma high density lipoprotein instability via selective delipidation and apolipoprotein A-I desorption
-
Gillard BK, Courtney HS, Massey JB, Pownall HJ (2007) Serum opacity factor unmasks human plasma high density lipoprotein instability via selective delipidation and apolipoprotein A-I desorption. Biochemistry 46:12968-12978
-
(2007)
Biochemistry
, vol.46
, pp. 12968-12978
-
-
Gillard, B.K.1
Courtney, H.S.2
Massey, J.B.3
Pownall, H.J.4
-
11
-
-
55049110080
-
Properties of the products formed by the activity of serum opacity factor against human plasma high density lipoproteins
-
Pownall HJ, Courtney HS, Gillard BK, Massey JB (2008) Properties of the products formed by the activity of serum opacity factor against human plasma high density lipoproteins. Chem Phys Lipids 156:45-51
-
(2008)
Chem Phys Lipids
, vol.156
, pp. 45-51
-
-
Pownall, H.J.1
Courtney, H.S.2
Gillard, B.K.3
Massey, J.B.4
-
12
-
-
61749096293
-
Disruption of human plasma high density lipoproteins by streptococcal serum opacity factor requires labile apolipoprotein A-I
-
Han M, Gillard BK, Courtney HS, Ward K, Rosales C, Khant H, Ludtke SJ, Pownall HJ (2009) Disruption of human plasma high density lipoproteins by streptococcal serum opacity factor requires labile apolipoprotein A-I. Biochemistry 48:1481-1487
-
(2009)
Biochemistry
, vol.48
, pp. 1481-1487
-
-
Han, M.1
Gillard, B.K.2
Courtney, H.S.3
Ward, K.4
Rosales, C.5
Khant, H.6
Ludtke, S.J.7
Pownall, H.J.8
-
13
-
-
0022513842
-
Partially reassembled high density lipoproteins effects on cholesterol flux, synthesis, and esterification in normal human skin fibroblasts
-
Picardo M, Massey JB, Kuhn DE, Gotto AM Jr, Gianturco SH, Pownall HJ (1986) Partially reassembled high density lipoproteins effects on cholesterol flux, synthesis, and esterification in normal human skin fibroblasts. Arteriosclerosis 6:434-441
-
(1986)
Arteriosclerosis
, vol.6
, pp. 434-441
-
-
Picardo, M.1
Massey, J.B.2
Kuhn, D.E.3
Gotto Jr., A.M.4
Gianturco, S.H.5
Pownall, H.J.6
-
14
-
-
0034711306
-
High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI
-
Yancey PG, De la Llera-Moya M, Swarnakar S, Monzo P, Klein SM, Connelly MA, Johnson WJ, Williams DL, Rothblat GH (2000) High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI. J Biol Chem 275:36596-36604
-
(2000)
J Biol Chem
, vol.275
, pp. 36596-36604
-
-
Yancey, P.G.1
De La Llera-Moya, M.2
Swarnakar, S.3
Monzo, P.4
Klein, S.M.5
Connelly, M.A.6
Johnson, W.J.7
Williams, D.L.8
Rothblat, G.H.9
-
15
-
-
77950021400
-
HDL superphospholipidation enhances key steps in reverse cholesterol transport
-
Tchoua U, Gillard BK, Pownall HJ (2010) HDL superphospholipidation enhances key steps in reverse cholesterol transport. Atherosclerosis 209:430-435
-
(2010)
Atherosclerosis
, vol.209
, pp. 430-435
-
-
Tchoua, U.1
Gillard, B.K.2
Pownall, H.J.3
-
16
-
-
33748990619
-
Detergent-mediated phospholipidation of plasma lipoproteins increases HDL cholesterophilicity and cholesterol efflux via SR-BI
-
Pownall HJ (2006) Detergent-mediated phospholipidation of plasma lipoproteins increases HDL cholesterophilicity and cholesterol efflux via SR-BI. Biochemistry 45(38):11514-11522
-
(2006)
Biochemistry
, vol.45
, Issue.38
, pp. 11514-11522
-
-
Pownall, H.J.1
-
17
-
-
0023221153
-
Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products
-
Steinbrecher UP (1987) Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products. J Biol Chem 262:3603-3608
-
(1987)
J Biol Chem
, vol.262
, pp. 3603-3608
-
-
Steinbrecher, U.P.1
-
18
-
-
58149477561
-
Enhancing apolipoprotein A-I-dependent cholesterol efflux elevates cholesterol export from macrophages in vivo
-
Mukhamedova N, Escher G, D'Souza W, Tchoua U, Grant A, Krozowski Z, Bukrinsky M, Sviridov D (2008) Enhancing apolipoprotein A-I-dependent cholesterol efflux elevates cholesterol export from macrophages in vivo. J Lipid Res 49:2312-2322
-
(2008)
J Lipid Res
, vol.49
, pp. 2312-2322
-
-
Mukhamedova, N.1
Escher, G.2
D'Souza, W.3
Tchoua, U.4
Grant, A.5
Krozowski, Z.6
Bukrinsky, M.7
Sviridov, D.8
-
19
-
-
33845580066
-
ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL
-
Vaughan AM, Oram JF (2006) ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL. J Lipid Res 47:2433-2443
-
(2006)
J Lipid Res
, vol.47
, pp. 2433-2443
-
-
Vaughan, A.M.1
Oram, J.F.2
-
20
-
-
0020323642
-
Kinetics and mechanism of free cholesterol exchange between human serum high- and low-density lipoproteins
-
Lund-Katz S, Hammerschlag B, Phillips MC (1982) Kinetics and mechanism of free cholesterol exchange between human serum high- and low-density lipoproteins. Biochemistry 21:2964-2969
-
(1982)
Biochemistry
, vol.21
, pp. 2964-2969
-
-
Lund-Katz, S.1
Hammerschlag, B.2
Phillips, M.C.3
-
21
-
-
0021213188
-
Measurement and prediction of the rates of spontaneous transfer of phospholipids between plasma lipoproteins
-
Massey JB, Hickson D, She HS, Sparrow JT, Via DP, Gotto AM Jr, Pownall HJ (1984) Measurement and prediction of the rates of spontaneous transfer of phospholipids between plasma lipoproteins. Biochim Biophys Acta 794:274-280
-
(1984)
Biochim Biophys Acta
, vol.794
, pp. 274-280
-
-
Massey, J.B.1
Hickson, D.2
She, H.S.3
Sparrow, J.T.4
Via, D.P.5
Gotto Jr., A.M.6
Pownall, H.J.7
-
22
-
-
0025827317
-
Spontaneous phospholipid transfer: Development of a quantitative model
-
Pownall HJ, Bick DL, Massey JB (1991) Spontaneous phospholipid transfer: development of a quantitative model. Biochemistry 30:5696-5700
-
(1991)
Biochemistry
, vol.30
, pp. 5696-5700
-
-
Pownall, H.J.1
Bick, D.L.2
Massey, J.B.3
-
23
-
-
0032917836
-
Correlation of serum triglyceride and its reduction by ω-3 fatty acids with lipid transfer activity and the neutral lipid compositions of high-density and low-density lipoproteins
-
Pownall HJ, Brauchi D, Kilinç C, Osmundsen K, Pao Q, Payton- Ross C, Gotto AM, Ballantyne CM (1999) Correlation of serum triglyceride and its reduction by ω-3 fatty acids with lipid transfer activity and the neutral lipid compositions of high-density and low-density lipoproteins. Atherosclerosis 143:285-297
-
(1999)
Atherosclerosis
, vol.143
, pp. 285-297
-
-
Pownall, H.J.1
Brauchi, D.2
Kilinç, C.3
Osmundsen, K.4
Pao, Q.5
Payton-Ross, C.6
Gotto, A.M.7
Ballantyne, C.M.8
-
24
-
-
0029149363
-
Effects of acceptor particle size on the efflux of cellular free cholesterol
-
Davidson WS, Rodriguez WV, Lund-Katz S, Johnson WJ, Rothblat GH, Phillips MC (1995) Effects of acceptor particle size on the efflux of cellular free cholesterol. J Biol Chem 270:17106-17113
-
(1995)
J Biol Chem
, vol.270
, pp. 17106-17113
-
-
Davidson, W.S.1
Rodriguez, W.V.2
Lund-Katz, S.3
Johnson, W.J.4
Rothblat, G.H.5
Phillips, M.C.6
-
25
-
-
64749090059
-
Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux
-
Sankaranarayanan S, Oram JF, Asztalos BF, Vaughan AM, Lund- Katz S, Adorni MP, Phillips MC, Rothblat GH (2009) Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux. J Lipid Res 50:275-284
-
(2009)
J Lipid Res
, vol.50
, pp. 275-284
-
-
Sankaranarayanan, S.1
Oram, J.F.2
Asztalos, B.F.3
Vaughan, A.M.4
Lund-Katz, S.5
Adorni, M.P.6
Phillips, M.C.7
Rothblat, G.H.8
-
26
-
-
3042798281
-
ATPbinding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins
-
Wang N, Lan D, Chen W, Matsuura F, Tall AR (2004) ATPbinding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins. Proc Natl Acad Sci USA 101:9774-9779
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9774-9779
-
-
Wang, N.1
Lan, D.2
Chen, W.3
Matsuura, F.4
Tall, A.R.5
-
27
-
-
48749119847
-
Characterization and properties of pre beta-HDL particles formed by ABCA1-mediated cellular lipid efflux to apo A-I
-
Duong PT, Weibel GL, Lund-Katz S, Rothblat GH, Phillips MC (2008) Characterization and properties of pre beta-HDL particles formed by ABCA1-mediated cellular lipid efflux to apo A-I. J Lipid Res 49:1006-1014
-
(2008)
J Lipid Res
, vol.49
, pp. 1006-1014
-
-
Duong, P.T.1
Weibel, G.L.2
Lund-Katz, S.3
Rothblat, G.H.4
Phillips, M.C.5
-
28
-
-
77950894330
-
The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages
-
de la Llera-Moya M, Drazul-Schrader D, Asztalos BF, Cuchel M, Rader DJ, Rothblat GH (2010) The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages. Arterioscler Thromb Vasc Biol 30:796-801
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 796-801
-
-
Se La Llera-Moya, M.1
Drazul-Schrader, D.2
Asztalos, B.F.3
Cuchel, M.4
Rader, D.J.5
Rothblat, G.H.6
-
29
-
-
0020353561
-
Distribution of lecithin-cholesterol acyltransferase (LCAT) in human plasma lipoprotein fractions evidence for the association of active LCAT with low density lipoproteins
-
Chen CH, Albers JJ (1982) Distribution of lecithin-cholesterol acyltransferase (LCAT) in human plasma lipoprotein fractions evidence for the association of active LCAT with low density lipoproteins. Biochem Biophys Res Commun 107:1091-1096
-
(1982)
Biochem Biophys Res Commun
, vol.107
, pp. 1091-1096
-
-
Chen, C.H.1
Albers, J.J.2
-
30
-
-
0018120222
-
Human plasma lecithincholesterol acyltransferase: Characterization of cofactor-dependent phospholipase activity
-
Aron L, Jones S, Fielding CJ (1978) Human plasma lecithincholesterol acyltransferase: characterization of cofactor-dependent phospholipase activity. J Biol Chem 253:7220-7226
-
(1978)
J Biol Chem
, vol.253
, pp. 7220-7226
-
-
Aron, L.1
Jones, S.2
Fielding, C.J.3
-
31
-
-
0002410107
-
-
Saunders Publishing, Philadelphia
-
Havel RJ, Goldstein JL, Brown MS, Bondy PK, Rosenberg LE (1980) Lipoproteins and lipid transport in the context of metabolic disease. Saunders Publishing, Philadelphia, pp 393-494
-
(1980)
Lipoproteins and Lipid Transport in the Context of Metabolic Disease
, pp. 393-494
-
-
Havel, R.J.1
Goldstein, J.L.2
Brown, M.S.3
Bondy, P.K.4
Rosenberg, L.E.5
-
32
-
-
78651103050
-
Treatment of human HDL with serum opacity factor increases the rate of cholesterol ester uptake by human hepatoma cells
-
in press
-
Gillard BK, Rosales C, Lin H-Y, Courtney HS, Pownall HJ (2010) Treatment of human HDL with serum opacity factor increases the rate of cholesterol ester uptake by human hepatoma cells. Biochemistry (in press)
-
(2010)
Biochemistry
-
-
Gillard, B.K.1
Rosales, C.2
Lin, H.-Y.3
Courtney, H.S.4
Pownall, H.J.5
-
33
-
-
6344253356
-
Antiinflammatory properties of HDL
-
Barter PJ, Nicholls S, Rye KA, Anantharamaiah GM, Navab M, Fogelman AM (2004) Antiinflammatory properties of HDL. Circ Res 95(8):764-772
-
(2004)
Circ Res
, vol.95
, Issue.8
, pp. 764-772
-
-
Barter, P.J.1
Nicholls, S.2
Rye, K.A.3
Anantharamaiah, G.M.4
Navab, M.5
Fogelman, A.M.6
-
34
-
-
0037389415
-
HDL counterbalance the proinflammatory effect of oxidized LDL by inhibiting intracellular reactive oxygen species rise, proteasome activation, and subsequent NF-kappaB activation in smooth muscle cells
-
Robbesyn F, Garcia V, Auge N, Vieira O, Frisach MF, Salvayre R, Negre-Salvarye A (2003) HDL counterbalance the proinflammatory effect of oxidized LDL by inhibiting intracellular reactive oxygen species rise, proteasome activation, and subsequent NF-kappaB activation in smooth muscle cells. FASEB J 17(6):743-745
-
(2003)
FASEB J
, vol.17
, Issue.6
, pp. 743-745
-
-
Robbesyn, F.1
Garcia, V.2
Auge, N.3
Vieira, O.4
Frisach, M.F.5
Salvayre, R.6
Negre-Salvarye, A.7
-
35
-
-
38849114338
-
Cholesterol efflux pathways and other potential mechanisms involved in the athero-protective effect of high density lipoproteins
-
Tall AR (2008) Cholesterol efflux pathways and other potential mechanisms involved in the athero-protective effect of high density lipoproteins. J Intern Med 263(3):256-273
-
(2008)
J Intern Med
, vol.263
, Issue.3
, pp. 256-273
-
-
Tall, A.R.1
-
36
-
-
33846488058
-
Mechanisms of disease: HDL metabolism as a target for novel therapies
-
Rader DJ (2007) Mechanisms of disease: HDL metabolism as a target for novel therapies. Nat Clin Pract Cardiovasc Med 4:102-109
-
(2007)
Nat Clin Pract Cardiovasc Med
, vol.4
, pp. 102-109
-
-
Rader, D.J.1
-
37
-
-
27644537437
-
Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: The importance of lesion stage and phagocytic efficiency
-
Tabas I (2005) Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: The importance of lesion stage and phagocytic efficiency. Arterioscler Thromb Vasc Biol 25:2255-2264
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 2255-2264
-
-
Tabas, I.1
-
38
-
-
67651085117
-
Lecithin-cholesterol acyltransferase expression has minimal effects on macrophage reverse cholesterol transport in vivo
-
Tanigawa H, Billheimer JT, Tohyama J, Fuki IV, Ng DS, Rothblat GH, Rader DJ (2009) Lecithin-cholesterol acyltransferase expression has minimal effects on macrophage reverse cholesterol transport in vivo. Circulation 120:160-169
-
(2009)
Circulation
, vol.120
, pp. 160-169
-
-
Tanigawa, H.1
Billheimer, J.T.2
Tohyama, J.3
Fuki, I.V.4
Ng, D.S.5
Rothblat, G.H.6
Rader, D.J.7
|