Pipecolic acid derivatives as small-molecule inhibitors of the legionella MIP protein

Journal of Medicinal Chemistry

Volumn 54, Issue 1, 2011, Pages 277-283

  Juli, Christina ^a   Sippel, Martin ^a   Jäger, Jens ^b   Thiele, Alexandra ^c   Weiwad, Matthias ^c   Schweimer, Kristian ^d   Rösch, Paul ^d   Steinert, Michael ^b   Sotriffer, Christoph A ^a   Holzgrabe, Ulrike ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^c Max Planck Research Unit   (Germany)

^d UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 (BENZYLSULFONYL)PIPERIDINE 2 CARBOXYLIC ACID; 3 (3,4,5 TRIMETHOXYPHENYL)PROPYL 1 (BENZYLSULFONYL) PIPERIDINE 2 CARBOXYLATE; ANTIINFECTIVE AGENT; ETHYL 1 (BENZYLSULFONYL)PIPERIDINE 2 CARBOXYLATE; ETHYL PIPERIDINE 2 CARBOXYLATE; FK 506 BINDING PROTEIN; LIGAND; MOLECULAR SCAFFOLD; PIPECOLIC ACID DERIVATIVE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; COMPUTER ANALYSIS; DRUG SYNTHESIS; LEGIONELLA PNEUMOPHILA; NONHUMAN;

ANIMALS; BACTERIAL PROTEINS; BINDING SITES; CELL LINE; COLONY COUNT, MICROBIAL; GUINEA PIGS; LEGIONELLA PNEUMOPHILA; LEGIONNAIRES' DISEASE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PEPTIDYLPROLYL ISOMERASE; PIPECOLIC ACIDS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TACROLIMUS BINDING PROTEIN 1A;

EID: 78651066518     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm101156y     Document Type: Article

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