The effects of sampling procedures and storage conditions on short-term stability of blood-based biochemical markers of bone metabolism

Clinical Chemistry

Volumn 57, Issue 1, 2011, Pages 138-140

  Stokes, Felicity J ^a   Ivanov, Petko ^a   Bailey, Lisa M ^a   Fraser, William D ^b  

^a ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; BIOCHEMICAL MARKER; CARBOXY TERMINAL TELOPEPTIDE; EDETIC ACID; HEPARIN; LITHIUM; OSTEOCALCIN; PARATHYROID HORMONE;

BLOOD ANALYSIS; BLOOD SAMPLING; BONE METABOLISM; BONE TURNOVER; CONCENTRATION (PARAMETERS); ENZYME IMMUNOASSAY; HUMAN; HUMAN CELL; LETTER; METABOLIC BONE DISEASE; PROTEIN ANALYSIS; PROTEIN STABILITY; ROOM TEMPERATURE; SAMPLING;

BIOLOGICAL MARKERS; BLOOD SPECIMEN COLLECTION; BONE AND BONES; BONE DISEASES, METABOLIC; HUMANS; TEMPERATURE; TIME FACTORS;

EID: 78650990782     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2010.157289     Document Type: Letter

References (5)

1. Fraser WD. The burden of osteoporosis and the case for disease management. Dis Manag Clin Outcomes 2004;12:409-18.
2. Seibel MJ. Biochemical markers of bone remodeling. Endocrinol Metab Clin North Am 2003;32: 83-113.
3. Christgau S, Bitsch-Jensen O, Hanover Bjarnason N, Gamwell Henriksen E, Qvist P, Alexandersen P, Bang Henriksen D. Serum Cross- Laps for monitoring the response in individuals undergoing antiresorptive therapy. Bone 2000;26:505-11.
4. WHO. Use of anticoagulants in diagnostic laboratory investigations and stability of blood, plasma and serum samples. Geneva: WHO; 2002. http:// whqlibdoc.who.int/hq/2002/WHO-DIL-LAB-99.1-Rev.2.pdf (Accessed October 2010).
5. Rodríguez-Mendizábal M, Lucena MI, Cabello MR, Blanco E, López-Rodríguez B, Sánchez de la Cuesta F. Variations in blood levels of aminoglycosides related to in vitro anticoagulant usage. Ther Drug Monit 1998;20:88-91.