ETV6/RUNX1 (TEL/AML1) is a frequent prenatal first hit in childhood leukemia

Blood

Volumn 117, Issue 1, 2011, Pages 368-369

  Zuna, Jan ^a   Madzo, Jozef ^a   Krejci, Ondrej ^a   Zemanova, Zuzana ^a   Kalinova, Marketa ^a   Muzikova, Katerina ^a   Zapotocky, Michal ^a   Starkova, Julia ^a   Hrusak, Ondrej ^a   Horak, Jiri ^a   Trka, Jan ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MIXED LINEAGE LEUKEMIA PROTEIN; TRANSCRIPTION FACTOR ETV6; TRANSCRIPTION FACTOR RUNX1;

ABORTION; ACUTE LYMPHOBLASTIC LEUKEMIA; CHILDHOOD LEUKEMIA; FLUORESCENCE IN SITU HYBRIDIZATION; FUSION GENE; HUMAN; HUMAN TISSUE; LETTER; PRENATAL PERIOD; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL CORD BLOOD FLOW;

EID: 78650983451     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-09-309070     Document Type: Letter

References (3)

1. Lausten-Thomsen U, Madsen HO, Vestergaard TR, Hjalgrim H, Nersting J, Schmiegelow K. Prevalence of t(12;21)[ETV6-RUNX1]-positive cells in healthy neonates. Blood. 2011;117(1):186-189.
2. Mori H, Colman SM, Xiao Z, et al. Chromosome translocations and covert leukemic clones are generated during normal fetal development. Proc Natl Acad Sci U S A. 2002;99(12):8242-8247.
3. Trka J, Zuna J, Hrusak O, et al. No evidence for MLL/AF4 expression in normal cord blood samples. Blood. 1999;93(3):1106-1107; author reply 1108-1110.