Persistently increased acetaminophen concentrations in a patient with acute liver failure

Clinical Chemistry

Volumn 57, Issue 1, 2011, Pages 9-11

  Fong, Bonnie Mei Wah ^a   Siu, Tak Shing ^a   Tam, Sidney ^a  

^a QUEEN MARY HOSPITAL   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOTRANSFERASE; BILIRUBIN; PARACETAMOL;

ABDOMINAL PAIN; ADULT; AMINOTRANSFERASE BLOOD LEVEL; APPETITE DISORDER; ARTICLE; BILIRUBIN BLOOD LEVEL; BLOOD SAMPLING; CASE REPORT; COMATOSE PATIENT; CONFUSION; DRUG BLOOD LEVEL; DRUG OVERDOSE; FEMALE; HOSPITAL ADMISSION; HUMAN; INTERNATIONAL NORMALIZED RATIO; JAUNDICE; LIVER FAILURE; MALAISE; PROTHROMBIN TIME;

ACETAMINOPHEN; ADULT; BILIRUBIN; DIAGNOSIS, DIFFERENTIAL; FALSE POSITIVE REACTIONS; FEMALE; HUMANS; LIVER FAILURE, ACUTE; ULTRAFILTRATION;

EID: 78650975565     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2010.144527     Document Type: Article

References (10)

1. Meredith TJ, Vale JA. Paracetamol poisoning. In: Vale JA, Medredith TJ, eds. Poisoning: Diagnosis and treatment. London: Update Books; 1981. p 104-12.
2. Mitchell JR, Jollow DJ, Potter WZ, Davis DC, Gillette JR, Brodie BB. Acetaminophen-induced hepatic necrosis: I. Role of drug metabolism. J Pharmacol Exp Ther 1973;187:185-94.
3. Jollow DJ, Mitchell JR, Potter WZ, Davis DC, Gillette JR, Brodie BB. Acetaminophen-induced hepatic necrosis: II. Role of covalent binding in vivo. J Pharmacol Exp Ther 1973;187:195-202.
4. Potter WZ, Davis DC, Mitchell JR, Jollow DJ, Gillette JR, Brodie BB. Acetaminophen-induced hepatic necrosis: III. Cytochrome P-450-mediated covalent binding in vitro. J Pharmacol Exp Ther 1973;187:203-10.
5. Mitchell JR, Jollow DJ, Potter WZ, Gillette JR, Brodie BB. Acetaminopheninduced hepatic necrosis: IV. Protective role of glutathione. J Pharmacol Exp Ther 1973;187:211-7.
6. Ellenhorn MJ, Barceloux DG, eds. Medical toxicology: Diagnosis and treatment of human poisoning. New York: Elsevier Science; 1988. Chapter portion, Treatment; p 161-4. Portion of chapter 9: Acetaminophen (paracetamol).
7. Davern TJ, James LP, Hinson JA, Polson J, Larson AM, Fontana RJ, et al. Measurement of serum acetaminophen-protein adducts in patients with acute liver failure. Gastroenterology 2006;130:687-94.
8. Bertholf RL, Johnnsen LM, Bazooband A, Mansouri V. False-positive acetaminophen results in a hyperbilirubinemic patient. Clin Chem 2003;49:695-8.
9. Mayer M, Salpeter L. More on interference of N-acetylcysteine in measurement of acetaminophen. Clin Chem 1998;44:892-3.
10. da Fonseca-Wollheim F, Heinze KG, Lomsky K, Schreiner H. Serum ultrafiltration for the elimination of endogenous interfering substances in creatinine determination. J Clin Chem Clin Biochem 1988;26:523-5.