Adjuvant radiation therapy for distal pancreatic cancer: Is there a role?

Annals of Surgical Oncology

Volumn 17, Issue 12, 2010, Pages 3082-3084

  Czito, Brian G ^a   Willett, Christopher G ^a  

^a DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROPYRIMIDINE; GEMCITABINE;

CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER SURVIVAL; CHEMORADIOTHERAPY; EDITORIAL; HEALTH CARE QUALITY; HUMAN; LYMPH NODE METASTASIS; OVERALL SURVIVAL; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PANCREAS RESECTION; RADIATION INJURY; TREATMENT OUTCOME;

ADENOCARCINOMA; HUMANS; PANCREATIC NEOPLASMS; RADIOTHERAPY, ADJUVANT; TREATMENT OUTCOME;

EID: 78650975209     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-010-1356-x     Document Type: Editorial

References (11)

1. R Geer M Brennan 1993 Prognostic indicators for survival after resection of pancreatic adenocarcinoma Am J Surg. 165 68 72 1:STN:280:DyaK3s7hvVynsQ%3D%3D 10.1016/S0002-9610(05)80406-4 8380315 discussion 72-3
2. HA Burris 3rd MJ Moore J Andersen MR Green ML Rothenberg MR Modiano, et al. 1997 Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial J Clin Oncol. 15 2403 2413 1:CAS:528:DyaK2sXlsFKksLY%3D 9196156
3. M Kalser S Ellenberg 1985 Pancreatic cancer. Adjuvant combined radiation and chemotherapy following curative resection Arch Surg. 120 899 903 1:STN:280:DyaL2M3ltFSnsQ%3D%3D 4015380
4. J Herman M Swartz C Hsu J Winter TM Pawlik E Sugar, et al. 2008 Analysis of fluorouracil based adjuvant chemotherapy and radiation after pancreaticoduodenectomy for ductal adenocarcinoma of the pancreas: results of a large, prospectively collected database at the Johns Hopkins Hospital J Clin Oncol. 26 3503 3510 10.1200/JCO.2007.15.8469 18640931
5. J Klinkenbijl J Jeekel T Sahmoud R van Pel ML Couvreur CH Veenhof, et al. 1999 Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC gastrointestinal tract cancer cooperative group Ann Surg. 230 776 782 1:STN:280:DC%2BD3c%2FotFKkug%3D%3D 10.1097/00000658-199912000-00006 10615932 discussion 782-4 (Pubitemid 30191812)
6. J Neoptolemos D Stocken H Friess C Bassi JA Dunn H Hickey, et al. 2004 A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer N Engl J Med. 350 1200 1210 1:CAS:528:DC%2BD2cXit12rtr8%3D 10.1056/NEJMoa032295 15028824 (Pubitemid 38339364)
7. J Neoptolemos M Büchler DD Stocken P Ghaneh D Smith C Bassi, et al. 2009 ESPAC-3(v2): A multicenter, international, open-label, randomized, controlled phase III trial of adjuvant 5-fluorouracil/folinic acid (5-FU/FA) versus gemcitabine (GEM) in patients with resected pancreatic ductal adenocarcinoma J Clin Oncol 27 18s 10.1200/JCO.2009.22.4626 (suppl; abstr LBA4505)
8. W Regine K Winter R Abrams H Safran JP Hoffman A Konski, et al. 2008 Fluorouracil vs. gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trial JAMA. 299 1019 1026 1:CAS:528:DC%2BD1cXjtVSltL0%3D 10.1001/jama.299.9.1019 18319412 (Pubitemid 351347058)
9. Redmond KJ, Wolfgang CL, Sugar E, Ahn J, Nathan H, Laheru D, et al. Adjuvant chemoradiation therapy for adenocarcinoma of the distal pancreas. Ann Surg Oncol. 2010. doi: 10.1245/s10434-010-1200-3 [Epub ahead of print].
10. R Abrams K Winter W Regine H Safran JP Hoffman AA Konski, et al. 2007 Correlation of RTOG 9704 (adjuvant therapy of pancreatic adenocarcinoma) radiation therapy quality assurance scores with survival J Clin Oncol 25 18s 4523
11. W Sun C Leong Z Zhang JJ Lu 2010 Purposing the lymphatic target volume for elected radiation therapy for pancreatic cancer: A pooled analysis of clinical evidence Radiat Oncol. 5 28 10.1186/1748-717X-5-28 20398316