The role of endoscopic imaging of the small bowel in clinical practice

American Journal of Gastroenterology

Volumn 106, Issue 1, 2011, Pages 27-36

  Leighton, Jonathan A ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BALLOON ASSISTED ENTEROSCOPY; CAPSULE ENDOSCOPY; CELIAC DISEASE; CLINICAL PRACTICE; CROHN DISEASE; ENDOSCOPY; ENTERITIS; GASTROINTESTINAL HEMORRHAGE; PRIORITY JOURNAL; REVIEW; SMALL INTESTINE; SMALL INTESTINE TUMOR;

BALLOON DILATION; CAPSULE ENDOSCOPY; CELIAC DISEASE; CROHN DISEASE; DIAGNOSTIC IMAGING; DOUBLE-BALLOON ENTEROSCOPY; EDUCATION, MEDICAL, CONTINUING; ENDOSCOPES, GASTROINTESTINAL; ENDOSCOPY, GASTROINTESTINAL; EQUIPMENT DESIGN; EQUIPMENT SAFETY; FEMALE; FORECASTING; GASTROINTESTINAL HEMORRHAGE; HUMANS; INTESTINE, SMALL; MALE; SENSITIVITY AND SPECIFICITY;

EID: 78650969390     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2010.410     Document Type: Review

References (129)

1. Cave D, Fleischer DE, Heigh R et al. First study involving simultaneous ingestion of two video capsules (VCs): a comparison of Olympus VC and Given Imaging VC in the detection of obscure GI bleeding (OGIB) [abstract]. Gastrointest Endosc 2006; 63: AB171.
2. Rondonotti E, Villa F, Mulder CJ et al. Small bowel capsule endoscopy in 2007: indications, risks and limitations. World J Gastroenterol 2007; 13: 6140-9.
3. Lewis BS, Eisen GM, Friedman S. A pooled analysis to evaluate results of capsule endoscopy trials. Endoscopy 2005; 37: 960-5. Erratum in: Endoscopy. 2007;39(4):303.
4. Fry LC, De Petris G, Swain JM et al. Impaction and fracture of a video capsule in the small bowel requiring laparotomy for removal of the capsule fragments. Endoscopy 2005; 37: 674-6.
5. Cheifetz AS, Kornbluth AA, Legnani P et al. The risk of retention of the capsule endoscope in patients with known or suspected Crohn's disease. Am J Gastroenterol 2006; 101: 2218-22.
6. Monkemuller K, Fry LC, Bellutti M et al. Balloon-assisted enteroscopy: unifying double-balloon and single-balloon enteroscopy [letter to the editor]. Endoscopy 2008; 40: 537, author reply 539.
7. May A, Nachbar L, Ell C. Double-balloon enteroscopy (push-and-pull enteroscopy) of the small bowel: feasibility and diagnostic and therapeutic yield in patients with suspected small bowel disease. Gastrointest Endosc 2005; 62: 62-70.
8. Mehdizadeh S, Ross A, Gerson L et al. What is the learning curve associated with double-balloon enteroscopy? Technical details and early experience in 6 US tertiary care centers. Gastrointest Endosc 2006; 64: 740-50.
9. Nakamura M, Niwa Y, Ohmiya N et al. Preliminary comparison of capsule endoscopy and double-balloon enteroscopy in patients with suspected small-bowel bleeding. Endoscopy 2006; 38: 59-66.
10. Heine GD, Hadithi M, Groenen MJ et al. Double-balloon enteroscopy: indications, diagnostic yield, and complications in a series of 275 patients with suspected small-bowel disease. Endoscopy 2006; 38: 42-8.
11. May A, Ell C. Push-and-pull enteroscopy using the double-balloon technique/double-balloon enteroscopy. Dig Liver Dis 2006; 38: 932-8.
12. Ross AS, Semrad C, Waxman I et al. Enteral stent placement by double balloon enteroscopy for palliation of malignant small bowel obstruction. Gastrointest Endosc 2006; 64: 835-7.
13. Ell C, May A. Mid-gastrointestinal bleeding: capsule endoscopy and push-and-pull enteroscopy give rise to a new medical term. Endoscopy 2006; 38: 73-5.
14. Yamamoto H, Sekine Y, Sato Y et al. Total enteroscopy with a nonsurgical steerable double-balloon method. Gastrointest Endosc 2001; 53: 216-20.
15. Mensink PB, Haringsma J, Kucharzik T et al. Complications of double balloon enteroscopy: a multicenter survey. Endoscopy 2007; 39: 613-5.
16. Tsujikawa T, Saitoh Y, Andoh A et al. Novel single-balloon enteroscopy for diagnosis and treatment of the small intestine: preliminary experiences. Endoscopy 2008; 40: 11-5.
17. Vargo JJ, Upchurch B, Dumot JA et al. Clinical utility of the Olympus single balloon enteroscope: the initial US experience [abstract]. Gastrointest Endosc 2007; 65: AB90.
18. Akerman PA, Agrawal D, Chen W et al. Spiral enteroscopy: a novel method of enteroscopy by using the Endo-Ease Discovery SB overtube and a pediatric colonoscope. Gastrointest Endosc 2009; 69: 327-32.
19. Buscaglia JM, Dunbar KB, Okolo PI III et al. The spiral enteroscopy training initiative: results of a prospective study evaluating the Discovery SB overtube device during small bowel enteroscopy (with video). Endoscopy 2009; 41: 194-9.
20. Akerman PA, Cantero D. Complications of spiral enteroscopy in the first 2950 patients [abstract] [cited 26 July 2010]. Available at http://www. gastro2009.org/scien-prog/abstract-detail.php?navId=93&ssid=760.
21. Raju GS, Gerson L, Das A et al. American Gastroenterological Association. American Gastroenterological Association (AGA) Institute technical review on obscure gastrointestinal bleeding. Gastroenterology 2007; 133: 1697-717.
22. Elijah D, Daas A, Brady P. Capsule endoscopy for obscure GI bleeding yields a high incidence of significant treatable lesions within reach of standard upper endoscopy. J Clin Gastroenterol 2008; 42: 962-3.
23. Fry LC, Bellutti M, Neumann H et al. Incidence of bleeding lesions within reach of conventional upper and lower endoscopes in patients undergoing double-balloon enteroscopy for obscure gastrointestinal bleeding. Aliment Pharmacol Ther 2009; 29: 342-9.
24. Leaper M, Johnston MJ, Barclay M et al. Reasons for failure to diagnose colorectal carcinoma at colonoscopy. Endoscopy 2004; 36: 499-503.
25. Descamps C, Schmit A, Van Gossum A. " Missed " upper gastrointestinal tract lesions may explain " occult " bleeding. Endoscopy 1999; 31: 452-5.
26. Zaman A, Katon RM. Push enteroscopy for obscure gastrointestinal bleeding yields a high incidence of proximal lesions within reach of a standard endoscope. Gastrointest Endosc 1998; 47: 372-6.
27. Spiller RC, Parkins RA. Recurrent gastrointestinal bleeding of obscure origin: report of 17 cases and a guide to logical management. Br J Surg 1983; 70: 489-93.
28. Lin S, Rockey DC. Obscure gastrointestinal bleeding. Gastroenterol Clin N Am 2005; 34: 679-98.
29. Leighton JA, Goldstein J, Hirota W et al. Obscure gastrointestinal bleeding. Gastrointest Endosc 2003; 58: 650-5.
30. Triester SL, Leighton JA, Leontiadis GI et al. A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding. Am J Gastroenterol 2005; 100: 2407-18.
31. Pennazio M, Santucci R, Rondonotti E et al. Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases. Gastroenterology 2004; 126: 643-53.
32. Delvaux M, Fassler I, Gay G. Clinical usefulness of the endoscopic video capsule as the initial intestinal investigation in patients with obscure digestive bleeding: validation of a diagnostic strategy based on the patient outcome after 12 months. Endoscopy 2004; 36: 1067-73.
33. Ben Soussan E, Antonietti M, Herve S et al. Diagnostic yield and therapeutic implications of capsule endoscopy in obscure gastrointestinal bleeding. Gastroenterol Clin Biol 2004; 28: 1068-73.
34. Estevez E, Gonzalez-Conde B, Vazquez-Iglesias JL et al. Diagnostic yield and clinical outcomes after capsule endoscopy in 100 consecutive patients with obscure gastrointestinal bleeding. Eur J Gastroenterol Hepatol 2006; 18: 881-8.
35. Lai LH, Wong GL, Chow DK et al. Long-term follow-up of patients with obscure gastrointestinal bleeding after negative capsule endoscopy. Am J Gastroenterol 2006; 101: 1224-8.
36. Pasha SF, Leighton JA, Das A et al. Double-balloon enteroscopy and capsule endoscopy have comparable diagnostic yield in small-bowel disease: a meta-analysis. Clin Gastroenterol Hepatol 2008; 6: 671-6.
37. Chen X, Ran ZH, Tong JL. A meta-analysis of the yield of capsule endoscopy compared to double-balloon enteroscopy in patients with small bowel diseases. World J Gastroenterol 2007; 13: 4372-8.
38. Pasha SF, Leighton JA. How useful is capsule endoscopy for the selection of patients for double-balloon enteroscopy? Nat Clin Pract Gastroenterol Hepatol 2008; 5: 490-1.
39. Gerson L, Kamal A. Cost-effectiveness analysis of management strategies for obscure GI bleeding. Gastrointest Endosc 2008; 68: 920-36.
40. Monkemuller K, Neumann H, Meyer F et al. A retrospective analysis of emergency double-balloon enteroscopy for small-bowel bleeding. Endoscopy 2009; 41: 715-7.
41. Giuliani A, Caporale A, Teneriello F et al. Primary tumors of the small intestine. Int Surg 1985; 70: 331-4.
42. Schwartz GD, Barkin JS. Small bowel tumors. Gastrointest Endosc Clin N Am 2006; 16: 267-75.
43. Carey EJ, Leighton JA, Heigh RI et al. A single-center experience of 260 consecutive patients undergoing capsule endoscopy for obscure gastrointestinal bleeding. Am J Gastroenterol 2007; 102: 89-95.
44. Schwartz GD, Barkin JS. Small-bowel tumors detected by wireless capsule endoscopy. Dig Dis Sci 2007; 52: 1026-30.
45. Estevez E, Gonzalez-Conde B, Vazquez-Iglesias JL et al. Incidence of tumoral pathology according to study using capsule endoscopy for patients with obscure gastrointestinal bleeding. Surg Endosc 2007; 21: 1776-80.
46. Bailey AA, Debinski HS, Appleyard MN et al. Diagnosis and outcome of small bowel tumors found by capsule endoscopy: a three-center Australian experience. Am J Gastroenterol 2006; 101: 2237-43.
47. Urbain D, De Looze D, Demedts I et al. Video capsule endoscopy in smallbowel malignancy: a multicenter Belgian study. Endoscopy 2006; 38: 408-11.
48. Cobrin GM, Pittman RH, Lewis BS. Increased diagnostic yield of small bowel tumors with capsule endoscopy. Cancer 2006; 107: 22-7.
49. Flieger D, Keller R, May A et al. Capsule endoscopy in gastrointestinal lymphomas. Endoscopy 2005; 37: 1174-80.
50. Daum S, Wahnschaffe U, Glasenapp R et al. Capsule endoscopy in refractory celiac disease. Endoscopy 2007; 39: 455-8. Erratum in: Endoscopy. 2007;39(5):1 p following 458. Endoscopy. 2007;39(7):672.
51. Van Tuyl SA, van Noorden JT, Timmer R et al. Detection of small-bowel neuroendocrine tumors by video capsule endoscopy. Gastrointest Endosc 2006; 64: 66-72.
52. Johanssen S, Boivin M, Lochs H et al. The yield of wireless capsule endoscopy in the detection of neuroendocrine tumors in comparison with CT enteroclysis. Gastrointest Endosc 2006; 63: 660-5.
53. Costamagna G, Shah SK, Riccioni ME et al. A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease. Gastroenterology 2002; 123: 999-1005.
54. Selby W, Shackell N. A comparison between the M2A capsule and push enteroscopy for the investigation of obscure gastrointestinal bleeding [abstract]. J Gastroenterol Hepatol 2001; 16 (Suppl): A29.
55. Ell C, Remke S, May A et al. The first prospective controlled trial comparing wireless capsule endoscopy with push enteroscopy in chronic gastrointestinal bleeding. Endoscopy 2002; 34: 685-9.
56. Mylonaki M, Fritscher-Ravens A, Swain PC. Clinical results of wireless capsule endoscopy [abstract]. Gastrointest Endosc 2002; 55: AB146.
57. Pennazio M, Santucci R, Rondonotti E et al. Capsule endoscopy: diagnostic yield and comparison with push enteroscopy in patients with obscure gastrointestinal bleeding: the Italian multicentre experience [abstract]. Endoscopy 2002; 34 (Suppl 2): 91.
58. Delvaux MM, Saurin J-C, Gaudin J-L et al. Comparison of wireless endoscopic capsule and push-enteroscopy in patients with obscure occult/overt digestive bleeding: results of a prospective, blinded, multicenter trial [abstract]. Gastrointest Endosc 2002; 55: AB88.
59. Van Gossum A, Francois E, Schmit A et al. A prospective comparative study between push-enteroscopy and wireless video capsule in patients with obscure digestive bleeding [abstract]. Gastrointest Endosc 2002; 55: AB88.
60. Wong RF, Tuteja AK, Haslem DS et al. Video capsule endoscopy compared with standard endoscopy for the evaluation of small-bowel polyps in persons with familial adenomatous polyposis (with video). Gastrointest Endosc 2006; 64: 530-7.
61. Mata A, Llach J, Castells A et al. A prospective trial comparing wireless capsule endoscopy and barium contrast series for small-bowel surveillance in hereditary GI polyposis syndromes. Gastrointest Endosc 2005; 61: 721-5.
62. Schulmann K, Hollerbach S, Kraus K et al. Feasibility and diagnostic utility of video capsule endoscopy for the detection of small bowel polyps in patients with hereditary polyposis syndromes. Am J Gastroenterol 2005; 100: 27-37.
63. Burke CA, Santisi J, Church J et al. The utility of capsule endoscopy small bowel surveillance in patients with polyposis. Am J Gastroenterol 2005; 100: 1498-502.
64. Barkay O, Moshkowitz M, Fireman Z et al. Initial experience of videocapsule endoscopy for diagnosing small-bowel tumors in patients with GI polyposis syndromes. Gastrointest Endosc 2005; 62: 448-52.
65. Caspari R, Von Falkenhausen M, Krautmacher C et al. Comparison of capsule endoscopy and magnetic resonance imaging for the detection of polyps of the small intestine in patients with familial adenomatous polyposis or with Peutz-Jeghers'syndrome. Endoscopy 2004; 36: 1054-9.
66. Brown G, Fraser C, Schofield G et al. Video capsule endoscopy in Peutz- Jeghers syndrome: a blinded comparison with barium follow-through for detection of small-bowel polyps. Endoscopy 2006; 38: 385-90.
67. Iaquinto G, Fornasarig M, Quaia M et al. Capsule endoscopy is useful and safe for small-bowel surveillance in familial adenomatous polyposis. Gastrointest Endosc 2008; 67: 61-7.
68. Almeida N, Figueiredo P, Lopes S et al. Double-balloon enteroscopy and small bowel tumors: a South-European single-center experience. Dig Dis Sci 2009; 54: 1520-4.
69. Fry LC, Neumann H, Kuester D et al. Small bowel polyps and tumours: endoscopic detection and treatment by double-balloon enteroscopy. Aliment Pharmacol Ther 2008; 29: 135-42.
70. Koornstra JJ, de Vries EG, Porte RJ. Improvements in small bowel carcinoid diagnosis and staging: 18F-DOPA PET, capsule endoscopy and double balloon enteroscopy. Dig Liver Dis 2009; 41: e35-8.
71. Bellutti M, Fry LC, Schmitt J et al. Detection of neuroendocrine tumors of the small bowel by double balloon enteroscopy. Dig Dis Sci 2009; 54: 1050-8.
72. Monkemuller K, Fry LC, Ebert M et al. Feasibility of double-balloon enteroscopy-assisted chromoendoscopy of the small bowel in patients with familial adenomatous polyposis. Endoscopy 2007; 39: 52-7.
73. Gao H, van Lier MG, Poley JW et al. Endoscopic therapy of small-bowel polyps by double-balloon enteroscopy in patients with Peutz-Jeghers syndrome. Gastrointest Endosc 2010; 71: 768-73.
74. Matsumoto T, Esaki M, Yanaru-Fujisawa R et al. Small-intestinal involvement in familial adenomatous polyposis: evaluation by double-balloon endoscopy and intraoperative enteroscopy. Gastrointest Endosc 2008; 68: 911-9.
75. Ross A, Mehdizadeh S, Tokar J et al. Double balloon enteroscopy detects small bowel mass lesions missed by capsule endoscopy. Dig Dis Sci 2008; 53: 2140-3.
76. Herrerias JM, Caunedo A, Rodriguez-Tellez M et al. Capsule endoscopy in patients with suspected Crohn's disease and negative endoscopy. Endoscopy 2003; 35: 564-8.
77. Mow WS, Lo SK, Targan SR et al. Initial experience with wireless capsule enteroscopy in the diagnosis and management of inflammatory bowel disease. Clin Gastroenterol Hepatol 2004; 2: 31-40.
78. Marmo R, Rotondano G, Piscopo R et al. Capsule endoscopy versus enteroclysis in the detection of small-bowel involvement in Crohn's disease: a prospective trial. Clin Gastroenterol Hepatol 2005; 3: 772-6.
79. Marmo R, Rotondano G, Piscopo R et al. Meta-analysis: capsule enteroscopy vs conventional modalities in diagnosis of small bowel diseases. Aliment Pharmacol Ther 2005; 22: 595-604.
80. Triester SL, Leighton JA, Leontiadis GI et al. A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with non-stricturing small bowel Crohn's disease. Am J Gastroenterol 2006; 101: 954-64.
81. Dionisio PM, Leighton JA, Leontiadis GI et al. Capsule endoscopy (CE) has a significantly higher diagnostic yield in patients with suspected and established non-stricturing Crohn disease (NSCD): a meta-analysis [abstract]. Gastrointest Endosc 2007; 65: AB369.
82. Solem CA, Loft us EV Jr, Fletcher JG et al. Small-bowel imaging in Crohn's disease: a prospective, blinded 4-way comparison trial. Gastrointest Endosc 2008; 68: 255-66.
83. Mehdizadeh S, Chen GC, Barkodar L et al. Capsule endoscopy in patients with Crohn's disease: diagnostic yield and safety. Gastrointest Endosc 2010; 71: 121-7.
84. Lewis BS, Eisen GM, Friedman S. A pooled analysis to evaluate results of capsule endoscopy trials. Endoscopy 2005; 37: 960-5. Erratum in: Endoscopy. 2007;39(4):303.
85. Schoo R, Buening C, Ockenga J et al. Mucosal healing in the small intestine detected by wireless capsule endoscopy [abstract]. Gastroenterology 2006; 130 (4 Suppl 2): A-220.
86. Bourreille A, Jarry M, D'Halluin PN et al. Wireless capsule endoscopy versus ileocolonoscopy for the diagnosis of postoperative recurrence of Crohn's disease: a prospective study. Gut 2006; 55: 978-83.
87. Stewenius J, Adnerhill I, Ekelund G et al. Ulcerative colitis and indeterminate colitis in the city of Malmo, Sweden: a 25-year incidence study. Scand J Gastroenterol 1995; 30: 38-43.
88. Maunoury V, Savoye G, Bourreille A et al. Value of wireless capsule endoscopy in patients with indeterminate colitis (inflammatory bowel disease type unclassified). Inflamm Bowel Dis 2007; 13: 152-5.
89. Viazis N, Karamanolis DG. Indeterminate colitis: the role of wireless capsule endoscopy [letter to the editor]. Aliment Pharmacol Ther 2007; 25: 859, author reply 860.
90. Llach J, Mata A, Pellise M et al. The role of capsule endoscopy in patients with indeterminate colitis: preliminary results of a prospective trial [abstract] 5th International Conference on Capsule Endoscopy. Program and Abstracts 2006 Paris, France, p. 27.
91. Goldstein JL, Eisen GM, Lewis B, et al., Investigators. Video capsule endo scopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo. Clin Gastroenterol Hepatol 2005; 3: 133-41.
92. Graham DY, Opekun AR, Willingham FF et al. Visible small-intestinal mucosal injury in chronic NSAID users. Clin Gastroenterol Hepatol 2005; 3: 55-9.
93. Toy E, Rojany M, Sheikh R et al. Capsule endoscopy's impact on clinical management and outcomes: a single-center experience with 145 patients. Am J Gastroenterol 2008; 103: 3022-8.
94. Barkin JS, Friedman S. Wireless capsule endoscopy requiring surgical intervention: the world's experience [abstract]. Am J Gastroenterol 2002; 97 (9 Suppl 1): S298.
95. Cave D, Legnani P, de Franchis R, et al., ICCE. ICCE consensus for capsule retention. Endoscopy 2005; 37: 1065-7.
96. Sears DM, Avots-Avotins A, Culp K et al. Frequency and clinical outcome of capsule retention during capsule endoscopy for GI bleeding of obscure origin. Gastrointest Endosc 2004; 60: 822-7.
97. Signorelli C, Rondonotti E, Villa F et al. Use of the Given Patency System for the screening of patients at high risk for capsule retention. Dig Liver Dis 2006; 38: 326-30.
98. Herrerias JM, Leighton JA, Costamagna G et al. Agile patency system eliminates risk of capsule retention in patients with known intestinal strictures who undergo capsule endoscopy. Gastrointest Endosc 2008; 67: 902-9.
99. Spada C, Shah SK, Riccioni ME et al. Video capsule endoscopy in patients with known or suspected small bowel stricture previously tested with the dissolving patency capsule. J Clin Gastroenterol 2007; 41: 576-82.
100. Yamamoto H, Kita H, Sunada K et al. Clinical outcomes of double-balloon endoscopy for the diagnosis and treatment of small-intestinal diseases. Clin Gastroenterol Hepatol 2004; 2: 1010-6.
101. Numata M, Kodama M, Sasaki F et al. Usefulness of double-balloon endoscopy as a diagnostic and therapeutic method for small-intestinal involvement in patients with inflammatory bowel disease [abstract]. Gastrointest Endosc 2007; 65: AB188.
102. Ross AS, Leighton JA, Schembre D et al. Double balloon enteroscopy in Crohn's disease: findings and impact on management [abstract]. Gastroenterology 2007; 132 (4 Suppl 2): A-654.
103. Oshitani N, Yukawa T, Yamagami H et al. Evaluation of deep small bowel involvement by double-balloon enteroscopy in Crohn's disease. Am J Gastroenterol 2006; 101: 1484-9.
104. Kenji W, Hosomi S, Hirata N et al. Useful diagnostic strategy in combination capsule endoscopy with double balloon endoscopy for Crohn's disease [abstract]. 5th International Conference on Capsule Endoscopy, Program and Abstracts. 2006 Paris, France, p. 41.
105. Sunada K, Yamamoto H, Kita H et al. Clinical outcomes of enteroscopy using the double-balloon method for strictures of the small intestine. World J Gastroenterol 2005; 11: 1087-9.
106. Pohl J, May A, Nachbar L et al. Diagnostic and therapeutic yield of push-and-pull enteroscopy for symptomatic small bowel Crohn's disease strictures. Eur J Gastroenterol Hepatol 2007; 19: 529-34.
107. Lee BI, Choi H, Choi KY et al. Retrieval of a retained capsule endoscope by double-balloon enteroscopy. Gastrointest Endosc 2005; 62: 463-5.
108. Cellier C, Green PH, Collin P, et al., ICCE. ICCE consensus for celiac disease. Endoscopy 2005; 37: 1055-9.
109. Green PH, Rubin M. Capsule endoscopy in celiac disease. Gastrointest Endosc 2005; 62: 797-9.
110. Petroniene R, Dubcenco E, Baker JP et al. Given capsule endoscopy in celiac disease. Gastrointest Endosc Clin N Am 2004; 14: 115-27.
111. Petroniene R, Dubcenco E, Baker JP et al. Given capsule endoscopy in celiac disease: evaluation of diagnostic accuracy and interobserver agreement. Am J Gastroenterol 2005; 100: 685-94.
112. Hopper AD, Sidhu R, Hurlstone DP et al. Capsule endoscopy: an alternative to duodenal biopsy for the recognition of villous atrophy in coeliac disease? Dig Liver Dis 2007; 39: 140-5.
113. Rondonotti E, de Franchis R. Diagnosing coeliac disease: is the videocapsule a suitable tool? Dig Liver Dis 2007; 39: 145-7.
114. Rondonotti E, Spada C, Cave D et al. Video capsule enteroscopy in the diagnosis of celiac disease: a multicenter study. Am J Gastroenterol 2007; 102: 1624-31.
115. Muhammad A, Pitchumoni CS. Newly detected celiac disease by wireless capsule endoscopy in older adults with iron deficiency anemia. J Clin Gastroenterol 2008; 42: 980-3.
116. Biagi F, Rondonotti E, Campanella J et al. Video capsule endoscopy and histology for small-bowel mucosa evaluation: a comparison performed by blinded observers. Clin Gastroenterol Hepatol 2006; 4: 998-1003.
117. Ersoy O, Akin E, Ugras S et al. Capsule endoscopy findings in celiac disease. Dig Dis Sci 2009; 54: 825-9.
118. Maiden L, Elliott T, McLaughlin SD et al. A blinded pilot comparison of capsule endoscopy and small bowel histology in unresponsive celiac disease. Dig Dis Sci 2009; 54: 1280-3.
119. El-Matary W, Huynh H, Vandermeer B. Diagnostic characteristics of given video capsule endoscopy in diagnosis of celiac disease: a meta-analysis. J Laparoendosc Adv Surg Tech A 2009; 19: 815-20.
120. Culliford A, Daly J, Diamond B et al. The value of wireless capsule endoscopy in patients with complicated celiac disease. Gastrointest Endosc 2005; 62: 55-61.
121. Apostolopoulos P, Alexandrakis G, Giannakoulopoulou E et al. M2A wireless capsule endoscopy for diagnosing ulcerative jejunoileitis complicating celiac disease. Endoscopy 2004; 36: 247.
122. Joyce AM, Burns DL, Marcello PW et al. Capsule endoscopy findings in celiac disease associated enteropathy-type intestinal T-cell lymphoma. Endoscopy 2005; 37: 594-6.
123. Hadithi M, Al-toma A, Oudejans J et al. The value of double-balloon enteroscopy in patients with refractory celiac disease. Am J Gastroenterol 2007; 102: 987-96.
124. Fry LC, Bellutti M, Neumann H et al. Utility of double-balloon enteroscopy for the evaluation of malabsorption. Dig Dis 2008; 26: 134-9.
125. Rosch T, Adler A, Pohl H et al. A motor-driven single-use colonoscope controlled with a hand-held device: a feasibility study in volunteers. Gastrointest Endosc 2008; 67: 1139-46.
126. Bang S, Park JY, Jeong S et al. First clinical trial of the " MiRo " capsule endoscope by using a novel transmission technology: electric-field propagation. Gastrointest Endosc 2009; 69: 253-9.
127. Quirini M, Menciassi A, Scapellato S et al. Feasibility proof of a legged locomotion capsule for the GI tract. Gastrointest Endosc 2008; 67: 1153-8.
128. Sharma VK. The future is wireless: advances in wireless diagnostic and therapeutic technologies in gastroenterology. Gastroenterology 2009; 137: 434-9.
129. Malagelada C, De Iorio F, Azpiroz F et al. New insight into intestinal motor function via noninvasive endoluminal image analysis. Gastroenterology 2008; 135: 1155-62.