Chitosan as a condensing agent induces high gene transfection efficiency and low cytotoxicity of liposome

Journal of Bioscience and Bioengineering

Volumn 111, Issue 1, 2011, Pages 98-103

  Liu, Ruizhen ^a   Gan, Lu ^a   Yang, Xiangliang ^a   Xu, Huibi ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Chitosan; Cytotoxicity; Gene transfer; Liposome; Precondensed DNA

Indexed keywords

AGAROSE GEL; CATIONIC LIPOSOMES; CELL LINES; CELL TOXICITY; CLINICAL APPLICATION; CONDENSING AGENTS; DNA FLUORESCENCE; GENE TRANSFECTION; GREEN FLUORESCENT PROTEIN; IN-VITRO; IN-VIVO; LIPOPLEXES; MOUSE MODELS; PRECONDENSED DNA; RU(PHEN); TERNARY COMPLEX; TRANSFECTION ACTIVITY; TRANSFECTION EFFICIENCY;

CELL CULTURE; CHITOSAN; COMPLEXATION; CYTOTOXICITY; DNA; FLUORESCENCE; GENE TRANSFER; GENES; LIPOSOMES; PHOSPHOLIPIDS; ZETA POTENTIAL;

CHITIN;

CHITOSAN; DNA; GREEN FLUORESCENT PROTEIN; LIPOSOME; POLYLYSINE; TERNARY COMPLEX FACTOR;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL LINE; CELL STRAIN 3T3; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; IN VIVO GENE TRANSFER; IN VIVO STUDY; MALE; MOUSE; MUSCLE; NONHUMAN; PARTICLE SIZE; PROTEIN EXPRESSION; SERUM; TIBIA; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ANIMALS; CHITOSAN; DNA; GREEN FLUORESCENT PROTEINS; HEP G2 CELLS; HUMANS; LIPOSOMES; MALE; MICE; MICE, INBRED BALB C; NIH 3T3 CELLS; PARTICLE SIZE; TRANSFECTION; TRANSGENES;

EID: 78650966096     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2010.08.017     Document Type: Article

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