Successful immunoapheresis of bullous autoimmune diseases: Pemphigus vulgaris and pemphigoid gestationis;Erfolgreiche Immunapherese bullöser Autoimmunerkrankungen: Pemphigus vulgaris und Pemphigoid gestationis

JDDG - Journal of the German Society of Dermatology

Volumn 9, Issue 1, 2011, Pages 27-31

  Marker, Michael ^a   Derfler, Kurt ^b   Monshi, Babak ^a   Rappersberger, Klemens ^a  

^a KRANKENANSTALT RUDOLFSTIFTUNG   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

autoantibody levels; immunoadsorption; pemphigoid gestationis; pemphigus; rituximab

Indexed keywords

AUTOANTIBODY; AZATHIOPRINE; CORTICOSTEROID; DIFLUCORTOLONE VALERATE; DIPHENHYDRAMINE; GLOBAFFIN; IMMUNOGLOBULIN; IMMUNOSORBA; METHYLPREDNISOLONE; PREDNISOLONE; RITUXIMAB; STEROID; THERASORB; UNCLASSIFIED DRUG;

ADULT; ANTIBODY BLOOD LEVEL; APHERESIS; ARTICLE; AUTOIMMUNE SKIN DISEASE; BULLOUS SKIN DISEASE; CASE REPORT; DISEASE FREE INTERVAL; DISEASE SEVERITY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HAIR LOSS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOAPHERESIS; IMMUNOFLUORESCENCE; LOW DRUG DOSE; LYMPHOMA; MALE; MULTIPLE CYCLE TREATMENT; PEMPHIGOID GESTATIONIS; PEMPHIGUS VULGARIS; SKIN BURNING SENSATION; SYMPTOM; TREATMENT OUTCOME;

EID: 78650928740     PISSN: 16100379     EISSN: 16100387     Source Type: Journal    
DOI: 10.1111/j.1610-0387.2010.07500.x     Document Type: Article

References (15)

1. Amagai M, Tsunoda K, Zillikens D, Nagai T, Nishikawa T,. The clinical phenotype of Pemphigus is defined by the anti-desmoglein autoantibody profile. J Am Acad Dermatol 1999; 40: 167-70.
2. Harman KE, Seed PT, Gratian MJ, Bhogal BS, Challacombe SJ, Black MM,. The severity of cutaneous and oral pemphigus is related to desmoglein 1 and 3 antibody levels. Br J Dermatol 2001; 144: 775-80.
3. Vaughan Jones SA, Hern S, Nelson-Piercy C, Seed PT, Black MM,. A prospective study of 200 women with dermatoses of pregnancy correlating clinical findings with hormonal and immunopathological profiles. Br J Dermatol 1999; 141: 71-81.
4. Valeyrie L, Lebrune-Vignes B, Bodak N, Grossin M, Descamps V, Cricks B, Belaich S,. Pemphigoid gestationis: treatment by topical class I corticosteroid. Ann Dermatol Venerol 2001; 128: 638-40.
5. Toth GG, van de Meer JB, Jonkman MF,. Dexamethasone pulse therapy in pemphigus. J Eur Acad Dermatol Venereol 2002; 16: 607-11.
6. Zillikens D, Derfler K, Eming R, Fierlbeck G, Goebeler M, Hertl M, Hofmann SC, Karlhofer F, Kautz O, Nitschke M, Opitz A, Quist S, Rose C, Schanz S, Schmidt E, Shimanovich I, Michael M, Ziller F,. Recommendations for the use of immunoapheresis in the treatment of autoimmune bullous diseases. J Dtsch Dermatol Ges 2007; 5: 881-7.
7. Hertl M, Zillikens D, Borradori L, Bruckner-Tudermann L, Burckhard H, Eming R, Engert A, Goebeler M, Hofmann S, Hunzelmann N, Karlhofer F, Kautz O, Lippert U, Niedermeier A, Nitschke M, Pfütze M, Reiser M, Rose C, Schmidt E, Shimanovich I, Sticherling M, Wolff-Franke S,. Recommendations for the use of rituximab (anti-CD20 antibody) in the treatment of autoimmune bullous skin diseases. J Dtsch Dermatol Ges 2008; 6: 366-74.
8. Wöhrl S, Geusau A, Karhofer F, Derfler K, Stingl G, Zillikens D,. Pemphigoid gestationis: Treatment with immunoapheresis. J Dtsch Dermatol Ges 2003; 1: 126-30.
9. Schmidt E, Obe K, Bröcker EB, Zillikens D,. Serum levels of autoantibodies to BP180 correlate with disease activity in patients with bullous pemphigoid. Arch Dermatol 2000; 136: 174-8.
10. Günther C, Laske J, Frind A, Julius U, Pfeiffer C,. Successful therapy of pemphigus vulgaris with immunoadsorption using the Thera Sorb⢠adsorber. J Dtsch Dermatol Ges 2008; 6: 661-3.
11. Schmidt E, Hunzelmann N, Zillikens D, Bröcker ED, Goebelert M,. Rituxi-mab in refractory autoimmune bullous diseases. Clin Exp Dermatol 2006; 31: 503-8.
12. Pfütze M, Eming R, Kneisel A, Kuhlmann U, Hoyer J, Hertl M,. Clinical and immunological follow-up of pemphigus patients on adjuvant treatment with immunoadsorption or rituximab. Dermatol 2009; 218: 237-45.
13. Eming R, Barth S, Kalden JR, Schuler G, Harrer T, Hertl M,. Prolonged clinical remission of patients with severe pemphigus upon rapid removal of desmoglein-reactive autoantibodies by immunoadsorption. Dermatol 2006; 212: 177-87.
14. Goldammer A, Derfler K, Herkner K, Bradwell AR, Hörl WH, Haas M,. Influence of plasma immunglobulin level on antibody synthesis. Blood 2002; 100 (1): 353-5.
15. Schmidt E, Zillikens D,. Immunoadsorption in dermatology. Arch Dermatol Res 2010; 302: 241-53.