One hundred years of allergen immunotherapy: Time to ring the changes

Journal of Allergy and Clinical Immunology

Volumn 127, Issue 1, 2011, Pages 3-7

  Durham, Stephen R ^a   Leung, Donald Y M ^b  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRASS POLLEN EXTRACT; HOUSE DUST ALLERGEN;

ALLERGEN IMMUNOTHERAPY; DESENSITIZATION; EVIDENCE BASED MEDICINE; GRASS POLLEN; HAY FEVER; HOUSE DUST ALLERGY; HUMAN; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOTHERAPY; PRIORITY JOURNAL; REVIEW; SUBCUTANEOUS IMMUNOTHERAPY; SUBLINGUAL IMMUNOTHERAPY;

EID: 78650908684     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2010.11.032     Document Type: Editorial

References (85)

1. L. Noon Prophylactic inoculation against hayfever Lancet 1 1911 1572
2. C. Prausnitz, and H. Küstner Studien über die Ueberempfindlichkeit Zentralbl Bakteriol 86 1921 160 169
3. R.A. Cooke, J.H. Barnard, S. Hebald, and A. Stull Serological immunity with co-existing sensitisation in a type of human allergy (hay fever) J Exp Med 62 1935 733 750
4. K. Ishizaka, T. Ishizaka, and M.M. Hornbrook Physiochemical properties of reaginic antibody V. Correlation of reaginic activity with yEglobulin antibody J Immunol 97 1966 840 853
5. Johansson SGO, Bennich H. Studies on a new class of human immunoglobulins. 1. Immunological properties. Nobel symposium 3, gamma globulins, structure and control of biosynthesis. P193. (Stockholm, June 12-17, 1967.) Almqvist and Wiksell.
6. G.J. Gleich, E.M. Zimmermann, L.L. Henderson, and J.W. Yunginger Effect of immunotherapy on immunoglobulin E and immunoglobulin G antibodies to ragweed antigens: a six-year prospective study J Allergy Clin Immunol 70 1982 261 271
7. M.H. Shamji, L.K. Wilcock, P.A. Wachholz, R.J. Dearman, I. Kimber, and P.A. Wurtzen The IgE-facilitated allergen binding (FAB) assay: validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses J Immunol Methods 17 2006 71 79
8. P.S. Creticos, D.G. Marsh, D. Proud, A. Kagey-Sobotka, N.F. Adkinson Jr., and L. Friedhoff Responses to ragweed-pollen nasal challenge before and after immunotherapy J Allergy Clin Immunol 84 1989 197 205
9. G. Passalacqua, M. Albano, L. Fregonese, A. Riccio, C. Pronzato, and G.S. Mela Randomised controlled trial of local allergoid immunotherapy on allergic inflammation in mite-induced rhinoconjunctivitis Lancet 351 1998 629 632
10. J.O. Warner, J.F. Price, J.F. Soothill, and E.N. Hey Controlled trial of hyposensitisation to Dermatophagoides pteronyssinus in children with asthma Lancet 2 1978 912 915
11. S. Rak, A. Björnson, L. Hkanson, S. Sörenson, and P. Venge The effect of immunotherapy on eosinophil accumulation and production of eosinophil chemotactic activity in the lung of subjects with asthma during natural pollen exposure J Allergy Clin Immunol 88 1991 878 888
12. R.E. Rocklin, A.L. Sheffer, D.K. Greineder, and K.L. Melmon Generation of antigen-specific suppressor cells during allergy desensitization N Engl J Med 302 1980 1213 1219
13. C.A. Akdis, T. Blesken, M. Akdis, B. Wüthrich, and K. Blaser Role of interleukin 10 in specific immunotherapy J Clin Invest 1021 1998 98 106
14. C.A. Akdis, and M. Akdis Mechanisms of allergen-specific immunotherapy J Allergy Clin Immunol 127 2011 18 27
15. K. Yamanaka, A. Yuta, M. Kakeda, R. Sasaki, H. Kitagawa, and E.C. Gabazza Induction of IL-10-producing regulatory T cells with TCR diversity by epitope-specific immunotherapy in pollinosis J Allergy Clin Immunol 124 2009 842 845
16. V.A. Varney, Q.A. Hamid, M. Gaga, S. Ying, M. Jacobson, and A.J. Frew Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses J Clin Invest 92 1993 644 651
17. C. Ebner, U. Siemann, B. Bohle, M. Willheim, U. Wiedermann, and S. Schenk Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T-cell clones specific for Phl p 1, a major grass pollen allergen Clin Exp Allergy 27 1997 1007 1015
18. S.R. Durham, S. Ying, V.A. Varney, M.R. Jacobson, R.M. Sudderick, and I.S. Mackay Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma J Allergy Clin Immunol 97 1996 1356 1365
19. M.K. Tulic, P.O. Fiset, P. Christodoulopoulos, P. Vaillancourt, M. Desrosiers, and F. Lavigne Amb a 1-immunostimulatory oligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response J Allergy Clin Immunol 113 2004 235 241
20. A.W. Frankland Immunotherapy [allergy archives] J Allergy Clin Immunol 127 2011 160
21. J. Freeman Rush inoculation with special reference to hay fever treatment Lancet 1 1930 744
22. A.W. Frankland, and R. Augustin Prophylaxis of summer hayfever and asthma: controlled trial comparing crude grass pollen extracts with isolated main protein component Lancet 1 1954 1055
23. M.A. Cox Calderon Subcutaneous specific immunotherapy for seasonal allergic rhinitis: a review of treatment practices in the US and Europe Curr Med Res Opin 26 2010 2723 2733
24. F.C. Lowell, and W. Franklin A double-blind study of the effectiveness and specificity of injection therapy in ragweed hay fever N Engl J Med 273 1965 675 679
25. P.S. Norman, and L.M. Lichtenstein The clinical and immunologic specificity of immunotherapy J Allergy Clin Immunol 61 1978 370 377
26. N.F. Adkinson Jr., P.A. Eggleston, D. Eney, E.O. Goldstein, K.C. Schuberth, and J.R. Bacon A controlled trial of immunotherapy for asthma in allergic children N Engl J Med 336 1997 324 331
27. D.E. Johnstone, and A. Dutton The value of hyposensitization therapy for bronchial asthma in children-a 14-year study Pediatrics 42 1968 793 802
28. L. Jacobsen, B. Niggemann, S. Dreborg, H.A. Ferdousi, S. Halken, and A. Høst Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year follow-up on the PAT study Allergy 62 2007 943 948
29. S. Zielen, P. Kardos, and E. Madonini Steroid-sparing effects with allergen-specific immunotherapy in children with asthma: a randomized controlled trial J Allergy Clin Immunol 126 2010 942 949
30. A.I. Tabar, S. Echechipia, B.E. Garcia, S. Martin, M.J. Alvarez-Puebla, and E. Arroabarren Three years of specific immunotherapy may be sufficient in house dust mite respiratory allergy J Allergy Clin Immunol 127 2011 63 67
31. K.J. Hunt, M.D. Valentine, A.K. Sobotka, A.W. Benton, F.J. Amodio, and L.M. Lichtenstein A controlled trial of immunotherapy in insect hypersensitivity N Engl J Med 299 1978 157 161
32. J. Bousquet, R. Lockey, and H.J. Malling Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper J Allergy Clin Immunol 102 1998 558 562
33. L. Haugaard, R. Dahl, and L. Jacobsen A controlled dose-response study of immunotherapy with standardized, partially purified extract of house dust mite: clinical efficacy and side effects J Allergy Clin Immunol 9 1993 709 722
34. A. Nanda, M. O'connor, M. Anand, S.C. Dreskin, L. Zhang, and B. Hines Dose dependence and time course of the immunologic response to administration of standardized cat allergen extract J Allergy Clin Immunol 114 2004 1339 1344
35. S.R. Durham, W.H. Yang, M.R. Pedersen, N. Johansen, and S. Rak Sublingual immunotherapy with once-daily grass allergen tablets: a randomized controlled trial in seasonal allergic rhinoconjunctivitis J Allergy Clin Immunol 117 2006 802 809
36. A. Didier, H.J. Malling, M. Worm, F. Horak, S. Jäger, and A. Montagut Optimal dose, efficacy, and safety of once-daily sublingual immunotherapy with a 5-grass pollen tablet for seasonal allergic rhinitis J Allergy Clin Immunol 120 2007 1338 1345
37. A.J. Frew, R.J. Powell, C.J. Corrigan, and S.R. Durham Efficacy and safety of specific immunotherapy with SQ allergen extract in treatment-resistant seasonal allergic rhinoconjunctivitis J Allergy Clin Immunol 117 2006 319 328
38. R. van Ree The CREATE partnership The CREATE project: EU support for the improvement of allergen standardization in Europe Allergy 59 2004 571 574
39. M.D. Chapman, F. Ferreira, M. Villalba, O. Cromwell, D. Bryan, and W.M. Becker The European Union CREATE project: a model for international standardization of allergy diagnostics and vaccines J Allergy Clin Immunol 122 2008 882 889
40. L.S. Cox, H. Nelson, R. Lockey, C. Calabria, T. Chacko, and I. Fingegold Allergen immunotherapy: a practice parameter third update J Allergy Clin Immunol 127 suppl 2011 S1 55
41. M.J. Abramson, R.M. Puy, and J.M. Weiner Allergen immunotherapy for asthma. An update Cochrane Database Syst Rev 4 2003 CD001186
42. M.A. Calderon, B. Alves, M. Jacobson, B. Hurwitz, A. Sheikh, and S. Durham Allergen injection immunotherapy for seasonal allergic rhinitis Cochrane Database Syst Rev 1 2007 CD001936
43. D.R. Wilson, M. Torres-Lima, and S.R. Durham Sublingual immunotherapy for allergic rhinitis: systematic review and meta-analysis Allergy 60 2005 4 12
44. A. Nieto, A. Mazon, R. Pamies, L. Bruno, M. Navarro, and A. Montanes Sublingual immunotherapy for allergic respiratory diseases: an evaluation of meta-analyses J Allergy Clin Immunol 24 2009 157 161
45. J.L. Brozek, J. Bousquet, C.E. Baena-Cagnani, S. Bonini, G.W. Canonica, and T.B. Casale Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision J Allergy Clin Immunol 126 2010 466 476
46. G.W. Canonica, C.E. Baena-Cagnani, J. Bousquet, P.J. Bousquet, R.F. Lockey, and H.J. Malling Recommendations for standardization of clinical trials with Allergen Specific Immunotherapy for respiratory allergy. A statement of a World Allergy Organization (WAO) taskforce Allergy 62 2007 317 324
47. P.J. Bousquet, J. Brozek, C. Bachert, T. Bieber, S. Bonini, and P. Burney The CONSORT statement checklist in allergen-specific immunotherapy: a GA2LEN paper Allergy 64 2009 1737 1745
48. P.J. Bousquet, M.A. Calderon, P. Demoly, D. Larenas, G. Passalacqua, and C. Bachert The CONSORT statement applied to allergen-specific immunotherapy with inhalant allergens. A GA2LEN paper J Allergy Clin Immunol 127 2011 49 56
49. M. Calderon, T.B. Casale, A. Togias, J. Bousquet, S.R. Durham, and P. Demoly Allergen-specific immunotherapy for respiratory allergies: from meta-analysis to registration and beyond J Allergy Clin Immunol 127 2011 30 38
50. U. Wahn, A. Tabar, P. Kuna, S. Halken, A. Montagut, and O. de Beaumont Efficacy and safety of 5-grass-pollen sublingual immunotherapy tablets in pediatric allergic rhinoconjunctivitis J Allergy Clin Immunol 123 2009 160 166
51. A. Bufe, P. Eberle, E. Franke-Beckmann, J. Funck, M. Kimmig, and L. Klimek Safety and efficacy in children of an SQ-standardized grass allergen tablet for sublingual immunotherapy J Allergy Clin Immunol 123 2009 167 173
52. M.A. Calderon, A.O. Birk, J.S. Andersen, and S.R. Durham Prolonged preseasonal treatment phase with Grazax sublingual immunotherapy increases clinical efficacy Allergy 62 2007 958 961
53. C. Hankin, and R.F. Lockey Patient characteristics associated with allergen immunotherapy initiation and adherence J Allergy Clin Immunol 127 2011 46 48
54. R.F. Lockey, and C. Hankin Health economics of allergen specific immunotherapy in the United States of America J Allergy Clin Immunol 127 2011 39 43
55. G.K. Scadding, and J. Brostoff Low dose sublingual therapy in patients with allergic rhinitis due to house dust mite Clin Allergy 16 1986 483 491
56. G.W. Canonica, J. Bousquet, T. Casale, R.F. Lockey, C.E. Baena-Cagnani, and R. Pawankar Sub-lingual immunotherapy: World Allergy Organization Position Paper 2009 Allergy 64 suppl 91 2009 1 59
57. L.S. Cox, D. Larenas Linnemann, H. Nolte, D. Weldon, I. Finegold, and H.S. Nelson Sublingual immunotherapy: a comprehensive review J Allergy Clin Immunol 117 2006 1021 1035
58. M. Larche Immune mechanisms of sublingual immunotherapy: are oral Langerhans cells the masters of tolerance? J Allergy Clin Immunol 126 2010 646 647
59. R. Dahl, A. Stender, and S. Rak Specific immunotherapy with SQ standardized grass allergen tablets in asthmatics with rhinoconjunctivitis Allergy 61 2006 185 190 (Pubitemid 43381828)
60. C. Bussmann, A. Böckenhoff, H. Henke, T. Werfel, and N. Novak Does allergen-specific immunotherapy represent a therapeutic option for patients with atopic dermatitis? J Allergy Clin Immunol 118 2006 1292 1298
61. S.D. Narisety, J.M. Skripak, P. Steele, R.G. Hamilton, E.C. Matsui, and A.W. Burks Open-label maintenance after milk oral immunotherapy for IgE-mediated cow's milk allergy J Allergy Clin Immunol 124 2009 610 612
62. S.M. Jones, L. Pons, J.L. Roberts, A.M. Scurlock, T.T. Perry, and M. Kulis Clinical efficacy and immune regulation with peanut oral immunotherapy J Allergy Clin Immunol 124 2009 292 300
63. K. Blumchen, H. Ulbricht, U. Staden, K. Dobberstein, J. Beschorner, and L.C. de Oliveira Oral peanut immunotherapy in children with peanut anaphylaxis J Allergy Clin Immunol 126 2010 83 91
64. A. Thyagarajan, P. Varshney, S.M. Jones, S. Sicherer, R. Wood, and B.P. Vickery Peanut oral immunotherapy is not ready for clinical use J Allergy Clin Immunol 126 2010 31 32
65. P. Varshney, P.H. Steele, B.P. Vickery, J.A. Bird, A. Thyagarajan, and A.M. Scurlock Adverse reactions during peanut oral immunotherapy home dosing J Allergy Clin Immunol 124 2009 1351 1352
66. S.M. Amar, R.J. Harbeck, M. Sills, L.J. Silveira, H. O'Brien, and H.S. Nelson Response to sublingual immunotherapy with grass pollen extract: monotherapy versus combination in a multiallergen extract J Allergy Clin Immunol 124 2009 150 156
67. W.G. Canonica, and G. Passalacqua Disease modifying effect and economic implications of sublingual immunotherapy J Allergy Clin Immunol 127 2011 44 45
68. S.R. Durham, S.M. Walker, E.M. Varga, M.R. Jacobson, F. O'Brien, and W. Noble Long-term clinical efficacy of grass-pollen immunotherapy N Engl J Med 341 1999 468 475
69. A. Des Roches, L. Paradis, J.-L. Menardo, S. Bouges, J.-P. Daures, and J. Bousquet Immunotherapy with a standardized Dermatophagoides pteronyssinus extract. VI. Specific immunotherapy prevents the onset of new sensitizations in children J Allergy Clin Immunol 99 1997 450 453
70. S.R. Durham, W. Emminger, A. Kapp, G. Colombo, J.G. de Monchy, and S. Rak Long-term clinical efficacy in grass pollen-induced rhinoconjunctivitis after treatment with SQ-standardized grass allergy immunotherapy tablet J Allergy Clin Immunol 125 2010 131 138
71. M. Marogna, I. Spadolini, A. Massolo, G.W. Canonica, and G. Passalacqua Long-lasting effects of sublingual immunotherapy according to its duration: a 15-year prospective study J Allergy Clin Immunol 126 2010 969 975
72. T.B. Casale, and J.R. Stokes Future forms of immunotherapy J Allergy Clin Immunol 127 2011 8 15
73. P.S. Norman, J.L. Ohman Jr., A.A. Long, P.S. Creticos, M.A. Gefter, and Z. Shaked Treatment of cat allergy with T-cell reactive peptides Am J Respir Crit Care Med 154 1996 1623 1628
74. W.L. Oldfield, M. Larche, and A.B. Kay Effect of T-cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: a randomised controlled trial Lancet 360 2002 47 53
75. C.J. Corrigan, J. Kettner, C. Doemer, O. Cromwell, A. Narkus Study Group Efficacy and safety of preseasonal-specific immunotherapy with an aluminium-adsorbed six-grass pollen allergoid Allergy 60 2005 801 807
76. P.S. Creticos, J.T. Schroeder, R.G. Hamilton, S.L. Balcer-Whaley, A.P. Khattignavong, and R. Lindblad Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis N Engl J Med 355 2006 1445 1455
77. K.J. Drachenberg, A.W. Wheeler, P. Stuebner, and F. Horak A well tolerated grass pollen- specific allergy vaccine containing a novel adjuvant, monophosphoryl lipid A, reduces allergic symptoms after only four preseasonal injections Allergy 56 2001 498 505
78. M. Jutel, L. Jäger, R. Suck, H. Meyer, H. Fiebig, and O. Cromwell Allergen-specific immunotherapy with recombinant grass pollen allergens J Allergy Clin Immunol 116 2005 608 613
79. G. Pauli, T.H. Larsen, S. Rak, F. Horak, E. Pastorello, and R. Valenta Efficacy of recombinant birch pollen vaccine for the treatment of birch-allergic rhinoconjunctivitis J Allergy Clin Immunol 122 2008 951 960
80. V. Niederberger, F. Horak, S. Vrtala, S. Spitzauer, M.T. Krauth, and P. Valent Vaccination with genetically engineered allergens prevents progression of allergic disease Proc Natl Acad Sci U S A 101 2004 14677 14682
81. R. Valenta, F. Ferreira, M. Focke-Tejkl, B. Linhart, V. Niederberger, and I. Swoboda From allergen genes to allergy vaccines Annu Rev Immunol 28 2010 211 241
82. G. Senti, B.M. Prinz Vavricka, I. Erdmann, M.I. Diaz, R. Markus, and S.J. McCormack Intralymphatic allergen administration renders specific immunotherapy faster and safer: a randomized controlled trial Proc Natl Acad Sci U S A 105 2008 17908 17912
83. G. Senti, N. Graf, S. Haug, N. Rüedi, S. von Moos, and T. Sonderegger Epicutaneous allergen administration as a novel method of allergen-specific immunotherapy J Allergy Clin Immunol 124 2009 997 1002
84. M. Larche, C.A. Akdis, and R. Valenta Immunological mechanisms of allergen specific immunotherapy Nat Rev Immunol 6 2006 761 771
85. G. Scadding, and S. Durham Mechanisms of sublingual immunotherapy J Asthma 46 2009 322 334