-
1
-
-
22844449583
-
The insulin resistance syndrome: definition and dietary approaches to treatment
-
Reaven G.M. The insulin resistance syndrome: definition and dietary approaches to treatment. Annu. Rev. Nutr. 2005, 25:391-406.
-
(2005)
Annu. Rev. Nutr.
, vol.25
, pp. 391-406
-
-
Reaven, G.M.1
-
2
-
-
17144429302
-
Calorie restriction, SIRT1 and metabolism: understanding longevity
-
Bordone L., Guarente L. Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat. Rev. Mol. Cell Biol. 2005, 6:298-305.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 298-305
-
-
Bordone, L.1
Guarente, L.2
-
3
-
-
33847764645
-
Aging, adiposity, and calorie restriction
-
Fontana L., Klein S. Aging, adiposity, and calorie restriction. JAMA 2007, 297:986-994.
-
(2007)
JAMA
, vol.297
, pp. 986-994
-
-
Fontana, L.1
Klein, S.2
-
4
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U., Cao Q., Yilmaz E., Lee A.H., Iwakoshi N.N., Ozdelen E., Tuncman G., Görgün C., Glimcher L.H., Hotamisligil G.S. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004, 306:457-461.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Görgün, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
5
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
Ozcan U., Yilmaz E., Ozcan L., Furuhashi M., Vaillancourt E., Smith R.O., Görgün C.Z., Hotamisligil G.S. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 2006, 313:1137-1140.
-
(2006)
Science
, vol.313
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Görgün, C.Z.7
Hotamisligil, G.S.8
-
6
-
-
57349110829
-
Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects
-
Sharma N.K., Das S.K., Mondal A.K., Hackney O.G., Chu W.S., Kern P.A., Rasouli N., Spencer H.J., Yao-Borengasser A., Elbein S.C. Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects. J. Clin. Endocrinol. Metab. 2008, 93:4532-4541.
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 4532-4541
-
-
Sharma, N.K.1
Das, S.K.2
Mondal, A.K.3
Hackney, O.G.4
Chu, W.S.5
Kern, P.A.6
Rasouli, N.7
Spencer, H.J.8
Yao-Borengasser, A.9
Elbein, S.C.10
-
7
-
-
62749178966
-
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss
-
Gregor M.F., Yang L., Fabbrini E., Mohammed B.S., Eagon J.C., Hotamisligil G.S., Klein S. Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss. Diabetes 2009, 58:693-700.
-
(2009)
Diabetes
, vol.58
, pp. 693-700
-
-
Gregor, M.F.1
Yang, L.2
Fabbrini, E.3
Mohammed, B.S.4
Eagon, J.C.5
Hotamisligil, G.S.6
Klein, S.7
-
8
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil G.S. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 2010, 140:900-917.
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
9
-
-
0036086064
-
The unfolded protein response in nutrient sensing and differentiation
-
Kaufman R.J., Scheuner D., Schröder M., Shen X., Lee K., Liu C.Y., Arnold S.M. The unfolded protein response in nutrient sensing and differentiation. Nat. Rev. Mol. Cell Biol. 2002, 3:411-421.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 411-421
-
-
Kaufman, R.J.1
Scheuner, D.2
Schröder, M.3
Shen, X.4
Lee, K.5
Liu, C.Y.6
Arnold, S.M.7
-
10
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D., Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 2007, 8:519-529.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
11
-
-
51249112769
-
Chemical induction of the unfolded protein response in the liver increases glucose production and is activated during insulin-induced hypoglycaemia in rats
-
Gonzales J.C., Gentile C.L., Pfaffenbach K.T., Wei Y., Wang D., Pagliassotti M.J. Chemical induction of the unfolded protein response in the liver increases glucose production and is activated during insulin-induced hypoglycaemia in rats. Diabetologia 2008, 51:1920-1929.
-
(2008)
Diabetologia
, vol.51
, pp. 1920-1929
-
-
Gonzales, J.C.1
Gentile, C.L.2
Pfaffenbach, K.T.3
Wei, Y.4
Wang, D.5
Pagliassotti, M.J.6
-
12
-
-
0001001689
-
Effects of food restriction on aging: separation of food intake and adiposity
-
Harrison D.E., Archer J.R., Astle C.M. Effects of food restriction on aging: separation of food intake and adiposity. Proc. Natl. Acad. Sci. USA 1984, 81:1835-1838.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 1835-1838
-
-
Harrison, D.E.1
Archer, J.R.2
Astle, C.M.3
-
13
-
-
58149177143
-
Mild electrical stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling
-
Morino S., Kondo T., Sasaki K., Adachi H., Suico M.A., Sekimoto E., Matsuda T., Shuto T., Araki E., Kai H. Mild electrical stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling. PLoS One 2008, 3:e4068.
-
(2008)
PLoS One
, vol.3
-
-
Morino, S.1
Kondo, T.2
Sasaki, K.3
Adachi, H.4
Suico, M.A.5
Sekimoto, E.6
Matsuda, T.7
Shuto, T.8
Araki, E.9
Kai, H.10
-
14
-
-
77955173247
-
Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice
-
Ishii N., Matsumura T., Kinoshita H., Fukuda K., Motoshima H., Senokuchi T., Nakao S., Tsutsumi A., Kim-Mitsuyama S., Kawada T., Takeya M., Miyamura N., Nishikawa T., Araki E. Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice. Arterioscler. Thromb. Vasc. Biol. 2010, 30:1598-1605.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 1598-1605
-
-
Ishii, N.1
Matsumura, T.2
Kinoshita, H.3
Fukuda, K.4
Motoshima, H.5
Senokuchi, T.6
Nakao, S.7
Tsutsumi, A.8
Kim-Mitsuyama, S.9
Kawada, T.10
Takeya, M.11
Miyamura, N.12
Nishikawa, T.13
Araki, E.14
-
15
-
-
0029939065
-
Decreased food intake does not completely account for adiposity reduction after ob protein infusion
-
Levin N., Nelson C., Gurney A., Vandlen R., de Sauvage F. Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proc. Natl. Acad. Sci. USA 1996, 93:1726-1730.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1726-1730
-
-
Levin, N.1
Nelson, C.2
Gurney, A.3
Vandlen, R.4
de Sauvage, F.5
-
16
-
-
0032925202
-
Effect of leptin deficiency on metabolic rate in ob/ob mice
-
Breslow M.J., Min-Lee K., Brown D.R., Chacko V.P., Palmer D., Berkowitz D.E. Effect of leptin deficiency on metabolic rate in ob/ob mice. Am. J. Physiol. 1999, 276:443-449.
-
(1999)
Am. J. Physiol.
, vol.276
, pp. 443-449
-
-
Breslow, M.J.1
Min-Lee, K.2
Brown, D.R.3
Chacko, V.P.4
Palmer, D.5
Berkowitz, D.E.6
-
17
-
-
36949001558
-
Leptin deficiency per se dictates body composition and insulin action in ob/ob mice
-
van den Hoek A.M., Teusink B., Voshol P.J., Havekes L.M., Romijn J.A., Pijl H. Leptin deficiency per se dictates body composition and insulin action in ob/ob mice. J. Neuroendocrinol. 2008, 20:120-127.
-
(2008)
J. Neuroendocrinol.
, vol.20
, pp. 120-127
-
-
van den Hoek, A.M.1
Teusink, B.2
Voshol, P.J.3
Havekes, L.M.4
Romijn, J.A.5
Pijl, H.6
-
18
-
-
61449095573
-
Leptin at 14y of age: an ongoing story
-
Friedman J.M. Leptin at 14y of age: an ongoing story. Am. J. Clin. Nutr. 2009, 89:973-979.
-
(2009)
Am. J. Clin. Nutr.
, vol.89
, pp. 973-979
-
-
Friedman, J.M.1
-
19
-
-
70349262248
-
Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice
-
Stranahan A.M., Lee K., Martin B., Maudsley S., Golden E., Cutler R.G., Mattson M.P. Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice. Hippocampus 2009, 19:951-961.
-
(2009)
Hippocampus
, vol.19
, pp. 951-961
-
-
Stranahan, A.M.1
Lee, K.2
Martin, B.3
Maudsley, S.4
Golden, E.5
Cutler, R.G.6
Mattson, M.P.7
-
20
-
-
35148901611
-
Characterization of weight loss and weight regain mechanisms after Roux-en-Y gastric bypass in rats
-
Guijarro A., Suzuki S., Chen C., Kirchner H., Middleton F.A., Nadtochiy S., Brookes P.S., Niijima A., Inui A., Meguid M.M. Characterization of weight loss and weight regain mechanisms after Roux-en-Y gastric bypass in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 293:1474-1489.
-
(2007)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.293
, pp. 1474-1489
-
-
Guijarro, A.1
Suzuki, S.2
Chen, C.3
Kirchner, H.4
Middleton, F.A.5
Nadtochiy, S.6
Brookes, P.S.7
Niijima, A.8
Inui, A.9
Meguid, M.M.10
-
21
-
-
0038623652
-
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake
-
Anson R.M., Guo Z., de Cabo R., Iyun T., Rios M., Hagepanos A., Ingram D.K., Lane M.A., Mattson M.P. Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Proc. Natl. Acad. Sci. USA 2003, 100:6216-6220.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 6216-6220
-
-
Anson, R.M.1
Guo, Z.2
de Cabo, R.3
Iyun, T.4
Rios, M.5
Hagepanos, A.6
Ingram, D.K.7
Lane, M.A.8
Mattson, M.P.9
-
22
-
-
57849115277
-
Endoplasmic reticulum stress plays a central role in development of leptin resistance
-
Ozcan L., Ergin A.S., Lu A., Chung J., Sarkar S., Nie D., Myers M.G., Ozcan U. Endoplasmic reticulum stress plays a central role in development of leptin resistance. Cell Metab. 2009, 9:35-51.
-
(2009)
Cell Metab.
, vol.9
, pp. 35-51
-
-
Ozcan, L.1
Ergin, A.S.2
Lu, A.3
Chung, J.4
Sarkar, S.5
Nie, D.6
Myers, M.G.7
Ozcan, U.8
-
23
-
-
0000567961
-
Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat
-
Barzilai N., Banerjee S., Hawkins M., Chen W., Rossetti L. Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. J. Clin. Invest. 1998, 101:1353-1361.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1353-1361
-
-
Barzilai, N.1
Banerjee, S.2
Hawkins, M.3
Chen, W.4
Rossetti, L.5
-
24
-
-
58149385620
-
Effect of weight loss on liver free fatty acid uptake and hepatic insulin resistance
-
Viljanen A.P., Iozzo P., Borra R., Kankaanpää M., Karmi A., Lautamäki R., Järvisalo M., Parkkola R., Rönnemaa T., Guiducci L., Lehtimäki T., Raitakari O.T., Mari A., Nuutila P. Effect of weight loss on liver free fatty acid uptake and hepatic insulin resistance. J. Clin. Endocrinol. Metab. 2009, 94:50-55.
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 50-55
-
-
Viljanen, A.P.1
Iozzo, P.2
Borra, R.3
Kankaanpää, M.4
Karmi, A.5
Lautamäki, R.6
Järvisalo, M.7
Parkkola, R.8
Rönnemaa, T.9
Guiducci, L.10
Lehtimäki, T.11
Raitakari, O.T.12
Mari, A.13
Nuutila, P.14
-
25
-
-
70350539531
-
Atf4 regulates obesity, glucose homeostasis, and energy expenditure
-
Seo J., Fortuno E.S., Suh J.M., Stenesen D., Tang W., Parks E.J., Adams C.M., Townes T., Graff J.M. Atf4 regulates obesity, glucose homeostasis, and energy expenditure. Diabetes 2009, 58:2565-2573.
-
(2009)
Diabetes
, vol.58
, pp. 2565-2573
-
-
Seo, J.1
Fortuno, E.S.2
Suh, J.M.3
Stenesen, D.4
Tang, W.5
Parks, E.J.6
Adams, C.M.7
Townes, T.8
Graff, J.M.9
-
26
-
-
44349163999
-
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice
-
Oyadomari S., Harding H.P., Zhang Y., Oyadomari M., Ron D. Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice. Cell Metab. 2008, 7:520-532.
-
(2008)
Cell Metab.
, vol.7
, pp. 520-532
-
-
Oyadomari, S.1
Harding, H.P.2
Zhang, Y.3
Oyadomari, M.4
Ron, D.5
-
27
-
-
70349226800
-
The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts
-
Yoshizawa T., Hinoi E., Jung D.Y., Kajimura D., Ferron M., Seo J., Graff J.M., Kim J.K., Karsenty G. The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts. J. Clin. Invest. 2009, 119:2807-2817.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2807-2817
-
-
Yoshizawa, T.1
Hinoi, E.2
Jung, D.Y.3
Kajimura, D.4
Ferron, M.5
Seo, J.6
Graff, J.M.7
Kim, J.K.8
Karsenty, G.9
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