Antibiotic therapy for the irritable bowel syndrome

New England Journal of Medicine

Volumn 364, Issue 1, 2011, Pages 81-82

  Tack, Jan ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

PROBIOTIC AGENT; PROTON PUMP INHIBITOR; RIFAXIMIN;

ANTIBIOTIC THERAPY; BACTERIAL OVERGROWTH; BREATH ANALYSIS; CLOSTRIDIUM DIFFICILE; CONSTIPATION; DRUG ABSORPTION; DRUG EFFICACY; EDITORIAL; HUMAN; IRRITABLE COLON; PRIORITY JOURNAL;

EID: 78650874332     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe1011211     Document Type: Editorial

References (10)

1. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology 2006;130:1480-91. [Erratum, Gastroenterology 2006;131: 688.]
2. Lee KJ, Tack J. Altered intestinal microbiota in irritable bowel syndrome. Neurogastroenterol Motil 2010;22:493-8.
3. Pimentel M, Chow EJ, Lin HC. Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome. Am J Gastroenterol 2000;95:3503-6.
4. Pimentel M, Chow EJ, Lin HC. Normalization of lactulose breath testing correlates with symptom improvement in irritable bowel syndrome: a double-blind, randomized, placebo-controlled study. Am J Gastroenterol 2003;98:412-9.
5. Pimentel M, Park S, Mirocha J, Kane SV, Kong Y. The effect of a nonabsorbed oral antibiotic (rifaximin) on the symptoms of the irritable bowel syndrome: a randomized trial. Ann Intern Med 2006;145:557-63.
6. Drossman DA. Treatment for bacterial overgrowth in the irritable bowel syndrome. Ann Intern Med 2006;145:626-8.
7. Pimentel M, Lembo T, Chey WD, et al. Rifaximin therapy for patients with irritable bowel syndrome without constipation. N Engl J Med 2011;364:22-32.
8. Layer P, Andresen V. Review article: rifaximin, a minimally absorbed oral antibacterial, for the treatment of travellers' diarrhoea. Aliment Pharmacol Ther 2010;31:1155-64.
9. Corazziari E, Bytzer P, Delvaux M, et al. Clinical trial guidelines for pharmacological treatment of irritable bowel syndrome. Aliment Pharmacol Ther 2003;18:569-80.
10. Ford AC, Spiegel BM, Talley NJ, Moayyedi P. Small intestinal bacterial overgrowth in irritable bowel syndrome: systematic review and meta-analysis. Clin Gastroenterol Hepatol 2009;7: 1279-86.