Changes of intestinal microflora in patients with rheumatoid arthritis during fasting or a mediterranean diet

Forschende Komplementarmedizin

Volumn 17, Issue 6, 2010, Pages 307-313

  Abendroth, Annalena ^a   Michalsen, Andreas ^b   Lüdtke, Rainer ^c   Rüffer, Andreas ^d   Musial, Frauke ^a   Dobos, Gustav J ^a   Langhorst, Jost ^a,e  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b Immanuel Hospital   (Germany)

^c Karl und Veronica Carstens Stiftung   (Germany)

^d Labor L+S AG   (Germany)

^e KLINIKEN ESSEN MITTE   (Germany)

Author keywords

Fasting; Intestinal microflora; Mediterranean diet; Nutrition; Rheumatic disease

Indexed keywords

VOLATILE FATTY ACID;

AGED; ANALGESIA; ARTICLE; BLOOD; BLOOD ANALYSIS; CLINICAL TRIAL; DIET RESTRICTION; DIET THERAPY; FECES; FEMALE; HUMAN; INTESTINE; MALE; MEDITERRANEAN DIET; MICROBIOLOGY; MIDDLE AGED; PATHOLOGY; QUALITY OF LIFE; RHEUMATOID ARTHRITIS; TIME; TREATMENT OUTCOME;

AGED; ARTHRITIS, RHEUMATOID; BLOOD CHEMICAL ANALYSIS; DIET, MEDITERRANEAN; FASTING; FATTY ACIDS, VOLATILE; FECES; FEMALE; HUMANS; INTESTINES; MALE; MIDDLE AGED; PAIN MANAGEMENT; QUALITY OF LIFE; TIME FACTORS; TREATMENT OUTCOME;

EID: 78650873385     PISSN: 16614119     EISSN: 16614127     Source Type: Journal    
DOI: 10.1159/000322313     Document Type: Article

References (39)

1. Symmons DP: Epidemiology of rheumatoid arthritis: determinants of onset, persistence and outcome. Best Pract Res Clin Rhematol 2002;16(5): 707-722.
2. Aletaha D, Smolen J: Rheumatoid arthritis: Target outcome for treatment. Z Rheumatol 2009;68(1): 10-5.
3. Kjeldsen-Kragh J, Haugen M, Borchgrevnik CF, Laerum E, Eek M, Mowinkel P, Hovi K, Forre O: Controlled trial of fasting and one-year vegetarian diet in rheumatoid arthritis. Lancet 1991;338(8772):899-902.
4. Kjeldsen-Kragh J, Haugen M, Forre O, Laache H, Malt UF: Vegetarian diet for patients with rheumatoid arthritis. Can the clinical effects be explained by the physiological characteristics of the patients? Br J Rheumatol 1994;33:569-575.
5. Hagen KB, Byfuglien MG, Falzon L, Olsen SU, Smedslund G: Dietary interventions for rheumatoid arthritis. Cochrane Database Syst Rev 2009;(1): CD006400.
6. Müller H, Wilhelmi de Toledo F, Resch KL: Fasting followed by vegetarian diet in patients with rheumatoid arthritis: a systematic review. Scand J Rheumatol 2001;30(1):1-10.
7. Michalsen A, Kuhlmann MK, Lüdtke R, Bäcker M, Langhorst J, Dobos GJ: Prolonged fasting in patients with chronic pain syndromes leads to late mood-enhancement not related to weight loss and fasting-induced leptin depletion. Nutr Neurosci 2006;9(5-6):195-200.
8. von Koerber K, Männle T, Leitzmann C: Vollwert- Ernährung - Konzeption einer zeitgemäßen und nachhaltigen Ernährung. Stuttgart, Haug 2004, pp 93-98.
9. Cleland LG, Hill CL, James MJ: Diet and arthritis. Baillieres Clin Rheumatol 1995;9(4):771-85.
10. Peltonen R, Ling WH, Hänninen O, Eerola E: An uncooked vegan diet shifts the profile of human faecal microflora: computerized analysis of direct stool sample gas-liquid chromatography profiles of bacterial cellular fatty acids. Appl Environ Microbiol 1992;58(11):3660-3666.
11. Michalsen A, Riegert M, Lüdtke R, Bäcker M, Langhorst J, Schwickert M, Dobos GJ: Mediterranean diet or extended fasting's influence on changing the intestinal microflora, immunoglobulin A secretion and clinical outcome in patients with rheumatoid arthritis and fibromyalgia: an observational study. BMC Complement Altern Med 2005;22(5):22.
12. Wong JMW, de Souza R, Kendall CWC, Emam A, Jenkins DJA: Colonic health: fermentation and short chain fatty acids. J Clin Gastroenterol 2006; 40(3):235-43.
13. Roediger WEW: Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut 1980;21:793-798.
14. Schröder O, Stein J: Kurzkettige Fettsäuren - Physiologie und pathophysiologische Implikationen. Akt Ernähr Med 1997;22:86-96.
15. Lührs H, Gerke T, Boxberger F, Backhaus K, Melcher R, Scheppach W, Menzel T: Butyrate inhibits interleukin-1-mediated nuclear factor - kappa b activation in human epithelial cells. Dig Dis Sci 2001;46(9):1968-73.
16. Tedelind S, Westberg F, Kjerrulf M, Vidal A: Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: A study with relevance to inflammatory bowel disease. World J Gastroenterol 2007;13(20):2826-2832.
17. Peltonen R, Nenonen M, Helve T, Hänninen O, Toivanen P, Eerola E: Faecal microbial flora and disease activity in rheumatoid arthritis during a vegan diet. Br J Rheumatol 1997;36(1):64-68.
18. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, Medseger TA, Mitchell DM, Neustadt DH, Pinals RS, Schaller JG, Sharp JT, Wilder RL Hunder GG: The American Rheumatism Association 1987 Revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31(3):315-24.
19. Buchinger O: Das Heilfasten und seine Hilfs methoden als biologischer Weg. Stuttgart, Hippokrates, 1999.
20. Wilhelmi de Toledo F, Buchinger A, Burggrabe H, Gaisbauer M, Hölz G, Kronsteiner W, Kuhn C, Lischka E, Lischka N, Lützner H, May W, Melchart D, Michalsen A, Müller H, Peper E, Resch KL, Ritzmann-Widderich M, Wessel A, Wichert H, Stange R: Leitlinien zur Fastentherapie. Forsch Komplemen tärmed Klass Naturheilkd 2002;9:189-198.
21. Linde L, Sorensen J, Ostergaard M, Horselv-Petersen K, Hetland ML: Health- Related Quality of Life: validity, reliability, and responsiveness of SF-36, EQ15D, EQ-5D, RAQoL and HAQ in patients with rheumatoid arthritis. J Rheumatol 2008;35(8):1528-37.
22. Roy CC, Kien CL, Bouthillier L, Levy E: Short-chain fatty acids: ready for prime time? Nutr Clin Pract 2006;21(4):351-66.
23. Haugen M, Kjeldsen-Kragh J, Nordvag BY, Forre O: Diet and disease symptoms in rheumatic disease - results of a questionnair based survey. Clin Rheumatol 1991;10(4):401-7.
24. Rennie KL, Hughes J, Lang R, Jebb SA: Nutritional management of rheumatoid arthritis: a review of the evidence. J Hum Nutr Diet 2003;16(2):97-109.
25. Remans PHJ, Sont JK, Wagenaar LW, Wouters-Wesseling W, Zuijderdiun WM, Jongma A, Breedveld FC, van Laar JM: Nutrient supplementation with polyunsaturated fatty acids and micronutrients in rheumatoid arthritis: clinical and biochemical effects. Eur J Clin Nutr 2004;58(6):839-45.
26. Gambhir JK, Lali P, Jain AK: Correlation between blood antioxidant levels and lipid peroxidation in rheumatoid arthritis. Clin Biochem 1997;30(4):351-355.
27. Öztürk Serdar H, Burak Cimen MY, Bölgen Cimen Ö, Kacmaz M, Durak I: Oxidant/antioxidant status of plasma samples from patients with rheumatoid arthritis. Rheumatol Int 1999;19:35-37.
28. Rao JK, Mihaliak K, Kroenke K, Bradley J, Tierney WM, Weinberger M: Use of complementary therapies for arthritis among patients of rheumatologists. Ann Intern Med 1999;131(6):409-16.
29. Peper E, Rogner J, Hettwer H: Stationäres Heilfasten - Prä-/Post-Befragung zum körperlichen und emotionalen Befinden sowie erlebten Veränderungen. Präv Rehab 1996;8(3):129-136.
30. Kjeldsen-Kragh J, Mellbye OJ, Haugen M, Mollnes TE, Hammer HB, Sioud M, Forre O: Changes in laboratory variables in rheumatoid arthritis during a trial of fasting and one-year vegetarian diet. Scand J Rheumatol 1995;24(2):85-93.
31. Fraser DA, Thoen J, Reseland JE, Forre O, Kjeldsen-Kragh J: Decreased CD4+ lymphocyte activation and increased interleukin-4 production in peripheral blood of rheumatoid arthritis patients after acute starvation. Clin Rheumatol 1999;18(5):394-401.
32. Peltonen R, Kjeldsen-Kragh J, Haugen M, Tuominen J, Toivanen P, Forre O, Eerola E: Changes of faecal flora in rheumatoid arthritis during fasting and one year vegetarian diet. Br J Rheumatol 1994; 33(7):638-643.
33. Mansson I, Norberg R, Olhagen B, Björklund NE: Arthritis in pigs induced by dietary factors. Microbiologic, clinical and histologic studies. Clin Exp Immunol 1971;9(5):677-93.
34. Severijnen AJ, Kool J, Swaak AJ, Hazenberg MP: Intestinal flora of patients with rheumatoid arthritis: induction of chronic arthritis in rats by cell wall fragments from isolated Eubacterium aerofaciens strains. Br J Rheumatol 1990; 29(6):433-9.
35. Kjeldsen-Kragh J, Rashid T, Dybwad A, Sioud M, Haugen M, Forre O, Ebringer A: Decrease in anti-Proteus mirabilis but not anti-Escherichia coli antibody levels in rheumatoid arthritis patients treated with fasting and a one year vegetarian diet. Ann Rheum Dis 1995;54:221-224.
36. Newkirk MM, Goldbach-Mansky R, Senior BW, Klippel J, Schumacher HR Jr, El-Gabalawy HS: Elevated levels of IgM and IgA antibodies to Proteus mirabilis and IgM antibodies to Escherichia coli are associated with early rheumatoid factor(RF)-positive rheumatoid arthritis. Rheumatology (Oxford) 2005; 44(11):1433-41.
37. Rombeau JL, Kripke SA: Metabolic and intestinal effects of short-chain fatty acids. JPEN Parenter Enteral Nutr 1990;14(5 suppl):181S-185S.
38. Royall D, Wolever TM, Jeejeebhoy KN: Clinical significance of colonic fermentation. Am J Gastroenterol 1990;85(10):1307-12.
39. Smedslund G, Byfuglien MG, Olsen SU, Hagen KB: Effectiveness and safety of dietary interventions for rheumatoid arthritis: a systematic review of randomized controlled trials. J Am Diet Assoc 2010;110(5):727-35.