Differential response of endothelial cells to simvastatin when conditioned with steady, non-reversing pulsatile or oscillating shear stress

Annals of Biomedical Engineering

Volumn 39, Issue 1, 2011, Pages 402-413

  Rossi, Joanna ^a,b   Jonak, Paul ^a   Rouleau, Leonie ^a,b   Danielczak, Lisa ^a   Tardif, Jean Claude ^b   Leask, Richard L ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MONTREAL HEART INSTITUTE   (Canada)

Author keywords

Atherosclerosis; Endothelial nitric oxide synthase; Kruppel like factor 2; Statins; Thrombomodulin

Indexed keywords

ATHEROSCLEROSIS; ENDOTHELIAL NITRIC OXIDE SYNTHASE; KRUPPEL-LIKE FACTORS; STATINS; THROMBOMODULIN;

CELL CULTURE; CONCENTRATION (PROCESS); CONTACTS (FLUID MECHANICS); DISEASES; FLUID MECHANICS; GLYCOPROTEINS; NITRIC OXIDE; OSCILLATING FLOW; PULSATILE FLOW; SELF ASSEMBLY; SHEAR STRESS; STRENGTH OF MATERIALS;

ENDOTHELIAL CELLS;

HYPOCHOLESTEROLEMIC AGENT; SIMVASTATIN;

ARTICLE; BLOOD FLOW VELOCITY; CELL CULTURE; DOSE RESPONSE; DRUG EFFECT; ENDOTHELIUM CELL; HUMAN; MECHANICAL STRESS; MECHANOTRANSDUCTION; PHYSIOLOGY; PULSATILE FLOW; SHEAR STRENGTH;

ANTICHOLESTEREMIC AGENTS; BLOOD FLOW VELOCITY; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; MECHANOTRANSDUCTION, CELLULAR; PULSATILE FLOW; SHEAR STRENGTH; SIMVASTATIN; STRESS, MECHANICAL;

EID: 78650866021     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-010-0145-9     Document Type: Article

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