Ropivacaine-induced late-onset systemic toxicity after transversus abdominis plane block under general anesthesia: Successful reversal with 20% lipid emulsion

Japanese Journal of Anesthesiology

Volumn 59, Issue 12, 2010, Pages 1502-1505

  Sakai, Toshiko ^a   Manabe, Wataru ^a   Kamitani, Taeko ^a   Takeyama, Eiko ^a   Nakano, Sonoko ^a  

^a Osaka Chuo Byoin   (Japan)

Author keywords

Late onset toxicity; Lipid emulsion; Ropivacaine; TAPblock

Indexed keywords

DIAZEPAM; HYPERTENSIVE AGENT; INTRALIPOS; ROPIVACAINE;

ADULT; ADVERSE DRUG REACTION; ARTICLE; CASE REPORT; CLONIC SEIZURE; ECHOGRAPHY; FEMALE; GENERAL ANESTHESIA; HUMAN; HYPOTENSION; LAPAROSCOPIC SURGERY; MYOMECTOMY; NERVE BLOCK; TRANSVERSUS ABDOMINIS PLANE BLOCK;

ABDOMINAL MUSCLES; ADULT; AMIDES; ANESTHESIA, GENERAL; ANESTHETICS, LOCAL; ANTIDOTES; FAT EMULSIONS, INTRAVENOUS; FEMALE; GYNECOLOGIC SURGICAL PROCEDURES; HUMANS; LAPAROSCOPY; LEIOMYOMA; NERVE BLOCK; OVERDOSE; TREATMENT OUTCOME; UTERINE NEOPLASMS;

EID: 78650863659     PISSN: 00214892     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Omura S, Kawada M, Ohta T, Yamamoto K, Kobayashi T. Systemic toxicity and resuscitation in bupivacaine-, levobupivacaine-, or ropivacaine-infused rats. Anesth Analg 2001 ; 93 : 743-8.
2. Knudsen K, Beckman Suurküla M, Blomberg S, Sjövall J, Edvardsson N. Central nervous and cardiovascular effects of i. v. infusions of ropivacaine, bupivacaine and placebo in volunteers. Br J Anaesthesia 1997 ; 78 : 507-14. (Pubitemid 27226361)
3. Chazalon P, Tourtier JP, Villevielle T, Giraud D, Saïssy JM, Mion G, et al. Ropivacaine-induced cardiac arrest after peripheral nerve block : Successful resuscitation. Anesthesiology 2003 ; 99 : 1449-51.
4. Copeland SE, Ladd LA, Gu XQ, Mather LE. The effects of general anesthesia on the central nervous system toxicity of local anesthetics. Anesth Analg 2008 ; 106 : 1429-39.
5. http://www.LipidRescue™
6. Weinberg G, Ripper R, Freinstein DL, Hoffman W. Lipid emulsion infusion rescues dogs from bupivacaine-induced cardiac toxicity. Reg Anesth Pain Med 2003 ; 28 : 198-202.
7. Rosenblatt MA, Abel M, Fisher GW, Itzkovich CJ, Eisenkraft JB. Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest. Anesthesiology 2006 ; 105 : 217-8.
8. Spence AG. Lipid reversal of central nervous system symptoms of bupivacaine toxicity. Anesthesiology 2007 ; 107 : 516-7.