Cortisol stimulates secretion of dehydroepiandrosterone in human adrenocortical cells through inhibition of 3βHSD2

Journal of Clinical Endocrinology and Metabolism

Volumn 96, Issue 1, 2011, Pages

  Topor, Lisa Swartz ^a,b   Asai, Masato ^a,b,c   Dunn, James ^a   Majzoub, Joseph A ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 BETA HYDROXYSTEROID DEHYDROGENASE TYPE II; ANDROSTENEDIONE; CORTISONE; CORTODOXONE; CYTOCHROME P450 17; CYTOCHROME P450 17A1; DEXAMETHASONE; GLUCOCORTICOID; HYDROCORTISONE; HYDROXYSTEROID DEHYDROGENASE; LYASE; MESSENGER RNA; PRASTERONE; PREDNISOLONE; SULFOTRANSFERASE; UNCLASSIFIED DRUG;

ADRENAL CORTEX CELL; ADRENARCHE; ANDROGEN RELEASE; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL STRAIN COS7; CHILDHOOD; COMPETITIVE INHIBITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOASSAY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REGULATORY MECHANISM; STEROIDOGENESIS; TANDEM MASS SPECTROMETRY; THIN LAYER CHROMATOGRAPHY; UNIVERSITY HOSPITAL;

EID: 78650858469     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2010-0692     Document Type: Article

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