Effect of HSP47 expression levels on hetero trimmer formation among type iv collagen α3, α4 and α5 chains

Biomedical Research

Volumn 31, Issue 6, 2010, Pages 371-377

  Kobayashi, Takehiro ^a   Uchiyama, Makoto ^a  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; COLLAGEN TYPE 4; COLLAGEN TYPE 4 ALPHA3 CHAIN; COLLAGEN TYPE 4 ALPHA4 CHAIN; COLLAGEN TYPE 4 ALPHA5 CHAIN; HEAT SHOCK PROTEIN 47; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; COLLAGEN SYNTHESIS; CONTROLLED STUDY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HETEROTRIMERIZATION; HUMAN; HUMAN CELL; POLYMERIZATION; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; QUALITY CONTROL; RNA INTERFERENCE;

COLLAGEN TYPE IV; HEK293 CELLS; HSP47 HEAT-SHOCK PROTEINS; HUMANS; KIDNEY GLOMERULUS; MUTATION; NEPHRITIS, HEREDITARY; PROTEIN MULTIMERIZATION;

FORMICIDAE;

EID: 78650840802     PISSN: 03886107     EISSN: 1880313X     Source Type: Journal    
DOI: 10.2220/biomedres.31.371     Document Type: Article

References (23)

1. Chen M, Costa FK, Lindvay CR, Han YP and Woodley DT (2002) The recombinant expression of full-length type VII collagen and characterization of molecular mechanisms underlying dystrophic epidermolysis bullosa. J Biol Chem 277, 2118-2124.
2. Gordon MK and Hahn RA (2010) Collagens. Cell Tissue Res 339, 247-257.
3. Gross O, Netzer KO, Lambrecht R, Seibold S and Weber M (2002) Meta-analysis of genotype-phenotype correlation in X-linked Alport syndrome: impact on clinical counselling. Nephrol Dial Transplant 17, 1218-1227.
4. Hosokawa N, Hohenadl C, Satoh M, Kühn K and Nagata K (1998) HSP47, a collagen-specifc molecular chaperone, delays the secretion of type III procollagen transfected in human embryonic kidney cell line 293: a possible role for HSP47 in collagen modifcation. J Biochem 124, 654-662.
5. Hudson BG, Tryggvason K, Sundaramoorthy M and Neilson EG (2003) Alport's syndrome, Goodpasture's syndrome, and type IV collagen. N Engl J Med 348, 2543-2556.
6. Ishida Y, Kubota H, Yamamoto A, Kitamura A, Bächinger HP and Nagata K (2006) Type I collagen in Hsp47-null cells is aggregated in endoplasmic reticulum and deficient in N-propeptide processing and fbrillogenesis. Mol Biol Cell 17, 2346-2355.
7. Kadler KE, Baldock C, Bella J and Boot-Handford RP (2007) Collagens at a glance. J Cell Sci 120, 1955-1958.
8. Khoshnoodi J, Cartailler JP, Alvares K, Veis A and Hudson BG (2006) Molecular recognition in the assembly of colla-gens: terminal noncollagenous domains are key recognition modules in the formation of triple helical protomers. J Biol Chem 281, 38117-38121.
9. Kobayashi T and Uchiyama M (2003) Characterization of assembly of recombinant type IV collagen α3, α4, and α5 chains in transfected cell strains. Kidney Int 64, 1986-1996.
10. Kobayashi T, Kakihara T and Uchiyama M (2008) Mutational analysis of type IV collagen α5 chain, with respect to hetero-trimer formation. Biochem Biophys Res Commun 366, 60-65.
11. Kobayashi T and Uchiyama M (2010) Mutant-type α5(IV) collagen in a mild form of Alport syndrome has residual ability to form a heterotrimer. Pediatr Nephrol 25, 1169- 1172.
12. Koide T, Asada S, Takahara Y, Nishikawa Y, Nagata K and Kitagawa K (2006) Specifc recognition of the collagen triple helix by chaperone HSP47: minimal structural requirement and spatial molecular orientation. J Biol Chem 281, 3432- 3438.
13. Lemmink HH, Schröder CH, Monnens LAH and Smeets HJM (1997) The clinical spectrum of type IV collagen mutations. Hum Mutat 9, 477-499.
14. Myllyharju J and Kivirikko KI (2004) Collagens, modifying enzymes and their mutations in humans, fies and worms. Trends Genet 20, 33-43.
15. Nagai N, Hosokawa M, Itohara S, Adachi E, Matsushita T, Hosokawa N and Nagata K (2000) Embryonic lethality of molecular chaperone Hsp47 knockout mice is associated with defects in collagen biosynthesis. J Cell Biol 150, 1499-1505.
16. Nagata K (1998) Expression and function of heat shock protein 47: a collagen-specifc molecular chaperone in the endo-plasmic reticulum. Matrix Biol 16, 379-386.
17. Nagata K (2003) HSP47 as a collagen-specific molecular chaperone: function and expression in normal mouse development. Semin Cell Dev Biol 14, 275-282.
18. Ruggiero F and Koch M (2008) Making recombinant extracellular matrix proteins. Methods 45, 75-85.
19. Satoh M, Hirayoshi K, Yokota SI, Hosokawa N and Nagata K (1996) Intracellular interaction of collagen-specifc stress protein HSP47 with newly synthesized procollagen. J Cell Biol 133, 469-483.
20. Taguchi T and Razzaque MS (2007) The collagen-specifc molecular chaperone HSP47: is there a role in fibrosis? Trends Mol Med 13, 45-53.
21. Tasab M, Batten MR and Bulleid NJ (2000) Hsp47: a molecular chaperone that interacts with and stabilizes correctly-folded procollagen. EMBO J 19, 2204-2211.
22. Tryggvason K and Martin P (2001) Alport syndrome and basement membrane collagen. In: The Metabolic and Molecular Bases of Inherited Disease (vol 4) (Scriver CR, Beaudet AL, Sly WS and Valle D, eds), pp 5453-5466, McGraw-Hill, New York.
23. Wilson JC, Yoon HS, Walker RJ and Eccles MR (2007) A novel Cys1638Tyr NC1 domain substitution in α5(IV) collagen causes Alport syndrome with late onset renal failure without hearing loss or eye abnormalities. Nephrol Dial Transplant 22, 1338-1346.