Effect of continuous posttraumatic intrathecal nocistatin on the development of mechanical allodynia

Regional Anesthesia and Pain Medicine

Volumn 36, Issue 1, 2011, Pages 32-35

  Hermanns, Henning ^a   Muth Selbach, Uta ^a   Krug, Sabrina ^a,b   Williams, Ruth ^a,b   Braun, Sebastian ^a   Werdehausen, Robert ^a   Schlösser, Lukas ^a   Bauer, Inge ^a  

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NOCISTATIN; PENTOBARBITAL;

ALLODYNIA; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BOLUS INJECTION; CATHETER; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG EFFICACY; DRUG INFUSION; FOOT INJURY; LIGATION; MALE; MECHANICAL ALLODYNIA; NERVE COMPRESSION; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; OSMOTIC MINIPUMP; PAIN ASSESSMENT; PRIORITY JOURNAL; RAT; SURGICAL TECHNIQUE;

ANALGESICS, OPIOID; ANIMALS; BEHAVIOR, ANIMAL; CATHETERIZATION; DISEASE MODELS, ANIMAL; HYPERALGESIA; INFUSION PUMPS, IMPLANTABLE; INFUSIONS, PARENTERAL; LIGATION; MALE; NEURALGIA; OPIOID PEPTIDES; PAIN MEASUREMENT; PAIN THRESHOLD; RATS; RATS, WISTAR; SCIATIC NERVE; SCIATIC NEUROPATHY; TIME FACTORS;

EID: 78650837621     PISSN: 10987339     EISSN: None     Source Type: Journal    
DOI: 10.1097/AAP.0b013e31820306b0     Document Type: Article

References (22)

1. Freynhagen R, Bennett MI. Diagnosis and management of neuropathic pain. BMJ. 2009;339:b3002.
2. Baron R, Binder A, Wasner G. Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment. Lancet Neurol. 2010;9:807-819.
3. Meunier J-C, Mollereau C, Toll L, et al. Isolation and structure of the endogenous agonist of opioid receptorYlike ORL1 receptor. Nature. 1995;377:532-535.
4. Reinscheid R, Nothacker H, Bourson A, et al. Orphanin FQ: a neuropeptide that activates an opioidlike G proteinYcoupled receptor. Science. 1995;270:792-794.
5. Okuda-Ashitaka E, Minami T, Tachibana S, et al. Nocistatin, a peptide that blocks nociceptin action in pain transmission. Nature. 1998;392:286-289.
6. Nakano H, Minami T, Abe K, et al. Effect of intrathecal nocistatin on the formalin-induced pain in mice versus that of nociceptin/orphanin FQ. J Pharmacol Exp Ther. 2000;292:331-336.
7. Xu I, Hashemi M, Caló G, Regoli D, Wiesenfeld-Hallin Z, Xu X. Effects of intrathecal nocistatin on the flexor reflex and its interaction with orphanin FQ nociceptin. Neuroreport. 1999;10:3681-3684.
8. Zeilhofer HU, Muth-Selbach U, Guhring H, Erb K, Ahmadi S. Selective suppression of inhibitory synaptic transmission by nocistatin in the rat spinal cord dorsal horn. J Neurosci. 2000;20:4922-4929.
9. Muth-Selbach U, Dybek E, Kollosche K, et al. The spinal antinociceptive effect of nocistatin in neuropathic rats is blocked by D-serine. Anesthesiology. 2004;101:753-758.
10. Lee T-L, Tachibana S. NocistatinVa new antinociceptive peptide. Reg Anesth Pain Med. 2000;25:408-410.
11. Bennett G, Xie Y. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain. 1988;33: 87-107.
12. Hermanns H, Muth-Selbach U, Williams R, et al. Differential effects of spinally applied glycine transporter inhibitors on nociception in a rat model of neuropathic pain. Neurosci Lett. 2008;445:214-219.
13. Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007;39:175-191.
14. Burton AW, Lee DH, Saab C, Chung JM. Preemptive intrathecal ketamine injection produces a long-lasting decrease in neuropathic pain behaviors in a rat model. Reg Anesth Pain Med. 1999;24:208-213.
15. Munglani R, Hudspith MJ, Fleming B, et al. Effect of pre-emptive NMDA antagonist treatment on long-term Fos expression and hyperalgesia in a model of chronic neuropathic pain. Brain Res. 1999;822:210-219. (Pubitemid 29222844)
16. Huang W, Simpson R. Long-term intrathecal administration of glycine prevents mechanical hyperalgesia in a rat model of neuropathic pain. Neurol Res. 2000;22:160-164.
17. Nong Y, Huang Y-Q, Ju W, et al. Glycine binding primes NMDA receptor internalization. Nature. 2003;422:302-307.
18. Mollereau C, Parmentier M, Mailleux P, et al. ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization. FEBS Lett. 1994;341:33-38.
19. Fantin M, Fischetti C, Trapella C, Morari M. Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic Gi/o protein linked pathways. Br J Pharmacol. 2007;152:549-555.
20. Ko MC, Wei H, Woods JH, Kennedy RT. Effects of intrathecally administered nociceptin/orphanin FQ in monkeys: behavioral and mass spectrometric studies. J Pharmacol Exp Ther. 2006;318:1257-1264.
21. Maier C, Baron R, TÖlle TR, et al. Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes. Pain. 2010;150:439-450.
22. Dohi T, Morita K, Kitayama T, Motoyama N, Morioka N. Glycine transporter inhibitors as a novel drug discovery strategy for neuropathic pain. Pharmacol Ther. 2009;123:54-79.