A biomimetic three-layered compartmented scaffold for vascular tissue engineering

2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10

Volumn , Issue , 2010, Pages 839-842

  Rainer, Alberto ^a   Centola, Matteo ^a   Spadaccio, Cristiano ^a   De Porcellinis, Stefano ^b   Abbruzzese, Franca ^a   Genovese, Jorge A ^a   Trombetta, Marcella ^a  

^a UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^b Biomatica Srl   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR TISSUES; CELL ELONGATION; CLINICAL USE; CYTOKINES; DRUG DELIVERY SYSTEM; ELECTROSPINNING TECHNIQUES; FUNCTIONALIZED; HUMAN MESENCHYMAL STEM CELLS; IN-CELL; INNER LAYER; MEDICAL FIELDS; MICROENVIRONMENTS; MULTI-LAYERED; OUTER LAYER; POLY-L-LACTIDE; THERAPEUTIC APPLICATION; VASCULAR GRAFTS; VASCULAR TISSUE ENGINEERING;

BIOMIMETICS; CELL CULTURE; DRUG DELIVERY; ENDOTHELIAL CELLS; GRAFTS; SCAFFOLDS; STEM CELLS; TISSUE;

TISSUE ENGINEERING;

BIOMIMETIC MATERIAL; TISSUE SCAFFOLD;

ARTICLE; BLOOD VESSEL; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; EQUIPMENT; EQUIPMENT DESIGN; EQUIPMENT FAILURE; GROWTH, DEVELOPMENT AND AGING; HUMAN; MESENCHYMAL STROMA CELL; PHYSIOLOGY; TISSUE ENGINEERING;

BIOMIMETIC MATERIALS; BLOOD VESSELS; CELL DIFFERENTIATION; CELLS, CULTURED; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; HUMANS; MESENCHYMAL STROMAL CELLS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 78650824780     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/IEMBS.2010.5626795     Document Type: Conference Paper

References (10)

1. M. Avci-Adali, G. Zieme, H.P. Wendel, "Induction of EPC homing on biofunctionalized vascular grafts for rapid in vivo selfendothelialization - a review of current strategies", Biotech Adv, 2010, 28:119-29
2. T. Shinoka, D. Shum-Tim, P.X. Ma, R.E. Tanel, R. Langer et al., "Creation of viable pulmonary artery autografts through tissue engineering", J Thorac Cardiovasc Surg, 1998, 115: 536-545.
3. C. Spadaccio, M. Chello, M. Trombetta, A. Rainer, Y. Toyoda, J.A. Genovese, "Drug releasing systems in cardiovascular tissue engineering", J Cell Mol Med, 2009, 13:422-39.
4. S.A. Sell, M.J. McClure, K. Garg, P.S. Wolfe, P.S. Wolfe, G. L. Bowlin, "Electrospinning of collagen/biopolymers for regenerative medicine and cardiovascular tissue engineering", Adv Dr Deliv Rev, 2009, 61: 1007-19.
5. S. Srouji, T. Kizhner, E. Suss-Tobi, E. Livne, E. Zussman, "3-D Nanofibrous electrospun multilayered construct is an alternative ECM mimicking scaffold", J Mater Sci Mater Med, 2008, 19: 1249-55.
6. C. Spadaccio, A. Rainer, M. Centola, M. Trombetta, M. Lusini, M. Chello et al, "A heparin releasing scaffold for stem cells: a differentiating device for vascular aims", Regen Med, 2010, to be published.
7. L.B. Jaques, T.K. Sue, N.M. Mcduffie, S.M. Wice, "Heparin and sulfated mucopolysaccharides--a micro system for quantitative differentiation and determination", Can J Physiol Pharmacol, 1977, 55: 1179-89.
8. S. Yan, Y. Xiaoqiang, L. Shuiping, M. Xiumei, S. Ramakrishna, "Controlled release of dual drugs from emulsion electrospun nanofibrous mats, Coll Surf B: Biointerf, 2009, 73: 376-81.
9. L. Moroni, R. Licht, J. de Boer, J.R. de Wijn, C.A. van Blitterswijk, "Fiber diameter and texture of electrospun PEOT/PBT scaffolds influence human mesenchymal stem cell proliferation and morphology, and the release of incorporated compounds", Biomaterials, 2006, 27: 4911-22.
10. J.M. Bezemer, R. Radersma, D.W. Grijpma, D.J. Dijkstra, J. Feijen, C.A. van Blitterswijk, "Zero-order release of lysozyme from poly(ethylene glycol)/ poly(butylene terephthalate) matrices", J Contr Rel, 2000, 64: 179-92.