Inhibition of phospholipase A2 increased the removal of the prion derived peptide PrP82-146 from cultured neurons

Neuropharmacology

Volumn 60, Issue 2-3, 2011, Pages 365-372

  Bate, Clive ^a   Ingham, Victoria ^a   Williams, Alun ^a  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

Author keywords

Cholesterol; Lysosomes; Phospholipase A2; Platelet activating factor; Prion

Indexed keywords

GINKGOLIDE B; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PRION PROTEIN; PRP82-146 PROTEIN; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; UNCLASSIFIED DRUG; ARACHIDONIC ACID DERIVATIVE; METHYL ARACHIDONYLFLUOROPHOSPHONATE; PEPTIDE FRAGMENT; PHOSPHONIC ACID DERIVATIVE; PRION PROTEIN (82 146); PRION PROTEIN (82-146);

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; LIPID RAFT; LYSOSOME; MOUSE; NERVE CELL; NONHUMAN; PRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN TARGETING; ANIMAL; BRAIN CORTEX; CELL CULTURE; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT;

ANIMALS; ARACHIDONIC ACIDS; CELLS, CULTURED; CEREBRAL CORTEX; HUMANS; MICE; NEURONS; PEPTIDE FRAGMENTS; PHOSPHOLIPASES A2; PHOSPHONIC ACIDS; PRIONS; PROTEIN TRANSPORT;

EID: 78650813872     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.10.001     Document Type: Article

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