Bistable Cell Fate Specification as a Result of Stochastic Fluctuations and Collective Spatial Cell behaviour

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Stockholm, Daniel ^a   Edom Vovard, Frédérique ^a   Coutant, Sophie ^a,b,c   Sanatine, Peggy ^a   Yamagata, Yoshiaki ^a,b,c   Corre, Guillaume ^a,b,c   le Guillou, Laurent ^d   Neildez Nguyen, Thi My Anh ^a,b,c   Pàldi, Andràs ^a,b,c  

^a GÉNÉTHON   (France)

^b UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

^c PSL RESEARCH UNIVERSITY   (France)

^d UNIVERSITÉ PARIS DIDEROT   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD56 ANTIGEN; SUPEROXIDE;

ARTICLE; CELL ACTIVITY; CELL DENSITY; CELL FATE; CELL INTERACTION; CELL MOTION; CELL SPECIFICITY; CELL SURFACE; CELLULAR DISTRIBUTION; COMPUTER SIMULATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MOLECULAR CLONING; MYOTUBE; PHENOTYPIC PLASTICITY; STEM CELL; STOCHASTIC MODEL; UPREGULATION; BIOLOGICAL MODEL; CELL COMMUNICATION; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; CELL SEPARATION; CYTOLOGY; DNA METHYLATION; FLOW CYTOMETRY; METABOLISM; MYOBLAST; PHENOTYPE; STATISTICS;

MAMMALIA;

ANTIGENS, CD56; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL SEPARATION; CELLS, CULTURED; COMPUTER SIMULATION; DNA METHYLATION; FLOW CYTOMETRY; HUMANS; MODELS, BIOLOGICAL; MYOBLASTS; PHENOTYPE; STOCHASTIC PROCESSES; SUPEROXIDES;

EID: 78650813064     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014441     Document Type: Article

References (32)

1. Stockholm D, Benchaouir R, Picot J, Rameau P, Neildez TM, et al. (2007) The origin of phenotypic heterogeneity in a clonal cell population in vitro. PLoS One 2: e394.
2. Chang HH, Hemberg M, Barahona M, Ingber DE, Huang S (2008) Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature 453: 544-547.
3. Kalmar T, Lim C, Hayward P, Munoz-Descalzo S, Nichols J, et al. (2009) Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells. PLoS Biol 7: e1000149.
4. Hayashi K, Lopes SM, Tang F, Surani MA (2008) Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. Cell Stem Cell 3: 391-401.
5. Snijder B, Sacher R, Ramo P, Damm EM, Liberali P, et al. (2009) Population context determines cell-to-cell variability in endocytosis and virus infection. Nature 461: 520-523.
6. Kaern M, Elston TC, Blake WJ, Collins JJ (2005) Stochasticity in gene expression: from theories to phenotypes. Nat Rev Genet 6: 451-464.
7. Raser JM, O'Shea EK (2005) Noise in gene expression: origins, consequences, and control. Science 309: 2010-2013.
8. Brock A, Chang H, Huang S (2009) Non-genetic heterogeneity-a mutationindependent driving force for the somatic evolution of tumours. Nat Rev Genet 10: 336-342.
9. Huang S, Eichler G, Bar-Yam Y, Ingber DE (2005) Cell fates as highdimensional attractor states of a complex gene regulatory network. Phys Rev Lett 94: 128701.
10. Neildez-Nguyen TM, Parisot A, Vignal C, Rameau P, Stockholm D, et al. (2008) Epigenetic gene expression noise and phenotypic diversification of clonal cell populations. Differentiation 76: 33-40.
11. Edom F, Mouly V, Barbet J, Fiszman M, Butler-Browne G (1994) Clones of human satellite cells can express in vitro both fast and slow myosin heavy chains. Developmental Biology 164: 219-229.
12. Capkovic KL, Stevenson S, Johnson MC, Thelen JJ, Cornelison DD (2008) Neural cell adhesion molecule (NCAM) marks adult myogenic cells committed to differentiation. Exp Cell Res 314: 1553-1565.
13. Tyson JJ, Chen KC, Novak B (2003) Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. Curr Opin Cell Biol 15: 221-231.
14. Ferrell JE, Xiong W (2001) Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible. Chaos 11: 227-236.
15. Paulsson J (2004) Summing up the noise in gene networks. Nature 427: 415-418.
16. Iezzi S, Cossu G, Nervi C, Sartorelli V, Puri PL (2002) Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. Proc Natl Acad Sci U S A 99: 7757-7762.
17. Wang L, Walker BL, Iannaccone S, Bhatt D, Kennedy PJ, et al. (2009) Bistable switches control memory and plasticity in cellular differentiation. Proc Natl Acad Sci U S A 106: 6638-6643.
18. Xiong W, Ferrell JE Jr. (2003) A positive-feedback-based bistable 'memory module' that governs a cell fate decision. Nature 426: 460-465.
19. Chang HH, Oh PY, Ingber DE, Huang S (2006) Multistable and multistep dynamics in neutrophil differentiation. BMC Cell Biol 7: 11.
20. Silva J, Smith A (2008) Capturing pluripotency. Cell 132: 532-536.
21. Orkin SH, Zon LI (2002) Hematopoiesis and stem cells: plasticity versus developmental heterogeneity. Nat Immunol 3: 323-328.
22. Hoffmann M, Chang HH, Huang S, Ingber DE, Loeffler M, et al. (2008) Noisedriven stem cell and progenitor population dynamics. PLoS One 3: e2922.
23. Paldi A (2003) Stochastic gene expression during cell differentiation: order from disorder? Cellular and Molecular Life Sciences 60: 1775-1779.
24. Huang S (2009) Reprogramming cell fates: reconciling rarity with robustness. Bioessays 31: 546-560.
25. Kashiwagi A, Urabe I, Kaneko K, Yomo T (2006) Adaptive response of a genetic network to environmental changes by fitness-induced attractor selection. PlosONE 1.
26. Kaneko K (1994) Relevance of dynamic clustering to biological networks. Physica D 75: 55-73.
27. Kupiec J (1983) A probabilist theory for cell differentiation, embryonic mortality and DNA C-value paradox. Specul Sci Technol 6: 471-478.
28. Laforge B, Guez D, Martinez M, Kupiec JJ (2005) Modeling embryogenesis and cancer: an approach based on an equilibrium between the autostabilization of stochastic gene expression and the interdependence of cells for proliferation. Prog Biophys Mol Biol 89: 93-120.
29. Furusawa C, Kaneko K (2008) A generic mechanism for adaptive growth rate regulation. Plos Computational Biology 4: e3.
30. Abou-Khalil R, Le Grand F, Pallafacchina G, Valable S, Authier FJ, et al. (2009) Autocrine and paracrine angiopoietin 1/Tie-2 signaling promotes muscle satellite cell self-renewal. Cell Stem Cell 5: 298-309.
31. Benchaouir R, Picot J, Greppo N, Rameau P, Stockholm D, et al. (2006) Combination of quantification and observation methods for study of "side population"cells in their "in vitro" microenvironment. Cytometry A 71: 251-257.
32. Baddeley A, Turner R (2005) Spatstat: an R package for analyzing spatial point patterns. Journal of Statistical Software 12: 1-42.