Control and Eradication of Brucella melitensis Infection in Sheep and Goats

Veterinary Clinics of North America - Food Animal Practice

Volumn 27, Issue 1, 2011, Pages 95-104

  Blasco, José M ^a   Molina Flores, Baldomero ^b  

^a CENTRO DE INVESTIGACIÓN Y TECNOLOGÍA AGROALIMENTARIA DE ARAGÓN CITA   (Spain)

^b Food and Agriculture Organization of the United Nations   (Tunisia)

Author keywords

Abortion; Brucella melitensis; Brucellosis; Control; Goat; Sheep

Indexed keywords

BRUCELLA VACCINE;

ANIMAL; ANIMAL DISEASE; BRUCELLA MELITENSIS; BRUCELLOSIS; DISEASE TRANSMISSION; GOAT; GOAT DISEASE; HUMAN; OCCUPATIONAL DISEASE; REVIEW; SHEEP; SHEEP DISEASE; ZOONOSIS;

ANIMALS; BRUCELLA MELITENSIS; BRUCELLA VACCINE; BRUCELLOSIS; GOAT DISEASES; GOATS; HUMANS; OCCUPATIONAL DISEASES; SHEEP; SHEEP DISEASES; ZOONOSES;

BRUCELLA MELITENSIS; CAPRA HIRCUS; OVIS ARIES;

EID: 78650802636     PISSN: 07490720     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cvfa.2010.10.003     Document Type: Review

References (26)

1. OIE Manual of diagnostic tests and vaccines for terrestrial animals 2008, OIE, Paris, p. 1343. 6th edition.
2. FAO Global livestock production and health atlas 2006, FAO, Rome (Italy), Electronic edition. Available at:, Accessed May 5, 2010. http://kids.fao.org/glipha/.
3. Pappas G., Papadimitriou P., Akritidis N., et al. The new global map of human brucellosis. Lancet Infect Dis 2006, 6:91-99.
4. WHO. The control of neglected zoonotic diseases: a route to poverty alleviation. In: Proceedings of a Joint WHO/DFID-AHP/FAO/OIE Meeting. Geneva (Switzerland): 20 and 21 September, 2005.
5. MacMillan A. Conventional serological tests. Animal brucellosis 1990, 153-198. CRC Press, Boca Raton (FL). K. Nielsen, J.R. Duncan (Eds.).
6. Blasco J.M., Garin-Bastuji B., Marín C.M., et al. Efficacy of different Rose Bengal and complement fixation antigens for the diagnosis of Brucella melitensis in sheep and goats. Vet Rec 1994, 134:415-420.
7. Blasco J.M., Marín C., De Bagués M.P., et al. Evaluation of allergic and serological tests for diagnosing Brucella melitensis infection in sheep. J Clin Microbiol 1994, 32:1835-1840.
8. Fensterbank R., Pardon P., Marly J. Comparison between subcutaneous and conjunctival route of vaccination of Rev-1 strain against B. melitensis infection in ewes. Ann Rech Vet 1982, 13:295-301.
9. De Bagués M.P.J., Marín C.M., Blasco J.M., et al. An ELISA with Brucella lipopolysaccharide antigen for the diagnosis of B. melitensis infection in sheep and for the evaluation of serological responses following subcutaneous or conjunctival B. melitensis Rev-1 vaccination. Vet Microbiol 1992, 30:233-241.
10. Díaz-Aparicio E., Marín C., Alonso B., et al. Evaluation of serological tests for diagnosis of B. melitensis infection of goats. J Clin Microbiol 1994, 32:1159-1165.
11. Díaz R., Garatea P., Jones L., et al. Radial immunodiffusion test with a Brucella polysaccharide antigen for differentiating infected from vaccinated cattle. J Clin Microbiol 1979, 10:37-41.
12. Marín C., Moreno E., Moriyón I., et al. Performance of competitive and indirect ELISAs, gel immunoprecipitation with native hapten polysaccharide and standard serological tests in diagnosis of sheep brucellosis. Clin Diagn Lab Immunol 1999, 6:269-272.
13. Muñoz P.M., Marín C.M., Monreal D., et al. Efficacy of several serological tests and antigens for diagnosis of bovine brucellosis in the presence of false-positive serological results due to Yersinia enterocolitica O:9. Clin Diagn Lab Immunol 2005, 12:141-151.
14. Maudlin I., Weber S. The control of neglected zoonotic diseases: a route to poverty alleviation 2006, WHO, Geneva (Switzerland), p. 54.
15. Blasco J.M. A review of the use of B. melitensis Rev-1 vaccine in adult sheep and goats. Prev Vet Med 1997, 31:275-281.
16. Al Khalaf S.A., Mohamad B.T., Nicoletti P. Control of brucellosis in Kuwait by vaccination of cattle, sheep and goats with Brucella abortus strain 19 or Brucella melitensis strain Rev-1. Trop Anim Health Prod 1992, 24:45-49.
17. Blasco J.M., Díaz R. Brucella melitensis Rev 1 vaccine as a cause of human brucellosis. Lancet 1993, 342:805.
18. Ariza J., Bosilkovski M., Cascio A., et al. Perspectives for the treatment of brucellosis in the 21st century: the Ioannina recommendations. PLoS Med 2007, 4:1872-1878.
19. González D., Grilló M.J., de Miguel M.J., et al. Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export. PLoS One 2008, 3:e2760.
20. Moriyón I., Grilló M.J., Monreal D., et al. Rough vaccines in animal brucellosis: structural and genetic basis and present status. Vet Res 2004, 35:1-38.
21. Mainar-Jaime RC, Marín CM, De Miguel MJ, et al. Experiences on the use of RB51 vaccine in Spain. In: Proceedings of the Brucellosis 2008 International Conference, London (United Kingdom): Veterinary Laboratory Agency; 2008. p. 40.
22. Villarroel M., Grell M., Saenz R. Isolation and identification of Brucella abortus RB51 in human: first report in Chile. Arch Med Vet 2000, 32:89-91.
23. Barrio M.B., Grilló M.J., Muñoz P.M., et al. Rough mutants defective in core and O-polysaccharide synthesis and export induce antibodies reacting in an indirect ELISA with smooth lipopolysaccharide and are less effective than Rev-1 vaccine against Brucella melitensis infection of sheep. Vaccine 2009, 27:1741-1749.
24. Blasco J.M. Existing and future vaccines against brucellosis in small ruminants. Small Rumin Res 2006, 62:33-37.
25. Jacques I., Verger J.M., Larocau K., et al. Immunological responses and protective efficacy against Brucella melitensis induced by bp26 and omp31 B. melitensis Rev.1 deletion mutants in sheep. Vaccine 2007, 25:794-805.
26. Grilló M.J., Marín C.M., Barberán M., et al. Efficacy of bp26 and bp26/omp31 B. melitensis Rev.1 deletion mutants against Brucella ovis in rams. Vaccine 2009, 27:187-191.