Frequency and susceptibility pattern of metallo-beta-lactamase producers in a hospital in Pakistan

Journal of Infection in Developing Countries

Volumn 4, Issue 12, 2010, Pages 810-813

  Kaleem, Fatima ^a   Usman, Javaid ^a   Hassan, Afreenish ^a   Khan, Aslam ^a  

^a NATIONAL UNIVERSITY OF SCIENCES AND TECHNOLOGY   (Pakistan)

Author keywords

Antimicrobial resistance; Carbapenem resistant Gram negative rods; Extended spectrum beta lactamase; Metallo beta lactamase

Indexed keywords

CARBAPENEM; METALLO BETA LACTAMASE; SULPERAZON;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATION; ENZYME SYNTHESIS; ESCHERICHIA COLI; FREQUENCY ANALYSIS; MORGANELLA MORGANII; NONHUMAN; PAKISTAN; PROVIDENCIA RETTGERI; PSEUDOMONAS AERUGINOSA;

ACINETOBACTER BAUMANNII; NEGIBACTERIA; PSEUDOMONAS AERUGINOSA;

EID: 78650796017     PISSN: 20366590     EISSN: 19722680     Source Type: Journal    
DOI: 10.3855/jidc.1050     Document Type: Article

References (25)

1. Watanabe M, Iyobe S, Inoue M, Mitsuhashi S (1991) Transferable imipenem resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother 35:147-51.
2. Lee K, Ha GY, Shin BM, Kim JJ, Kang JO, Jang SJ, Yong D, Chong Y (2004) Metallo-β-lactamase-producing Gram-negative bacilli in Korean Nationwide Surveillance of Antimicrobial Resistance group hospitals in 2003: continued prevalence of VIM-producing Pseudomonas spp. and increase of IMP producing Acinetobacter spp. Diagn Microbiol Infect Dis 50:51-58.
3. Yan JJ, Hsueh PR, Ko WC, Luh KT, Tsai SH, Wu HM, Lin YT, Wu JJ (2001) Metallo-β-lactamases in clinical Pseudomonas isolates in Taiwan and identification of VIM-3, a novel variant of the VIM-2 enzyme. Antimicrob Agents Chemother 45:2224-28.
4. Lagatolla C, Tonin EA, Monti-Bragadin C, Dolzani L, Gombac F, Bearzi C, Edalucci C (2004) Endemic carbapenem-resistant Pseudomonas aeruginosa with acquired Metallo-β-lactamase determinants in European hospital. Emerg Infect Dis 10:535-38.
5. Libisch B, Gacs M, Csiszar K, Muzslay M, Rokusz L, Fuzi M (2004) Isolation of an integron-borne blaVIM-4 type Metallo-β-lactamase gene from a carbapenem-resistant Pseudomonas aeruginosa clinical isolate in Hungary. Antimicrob Agents Chemother 48:3576-78.
6. Patzer J, Toleman MA, Deshpande LM, Kaminska W, Dzierzanowska D, Bennett PM, Jhons RN (2004) Pseudomonas aeruginosa strains harboring an unusual blaVIM-4 gene cassette isolated from hospitalized children in Poland (1998-2001). J. Antimicrob. Chemother 53:451-56.
7. Poirel L, Naas T, Nicolas D, Collet L, Bellais S, Cavallo JD, Nordman P (2000) Characterization of VIM-2, a carbapenems hydrolyzing Metallo-β-lactamase and its plasmid-and integron-borne gene from a Pseudomonas aeruginosa clinical isolate in France. Antimicrob Agents Chemother 44:891-97.
8. Peleg AY, Franklin C, Bell J, and Spelman DW (2004) Emergence of IMP-4 Metallo-β-lactamase in a clinical isolate from Australia. J Antimicrob Chemother. 54:699-700.
9. Kahan FM, Kropp H, Sundelof JG, Birnbaum J (1981) Thienamycin: development of imipenen-cilastatin. J Antimicrob Agents Chemother 12:1-35.
10. Ambler RP (1980) The structure of beta-lactamases. Philos Trans R Soc London Bio Sci 289:321-31.
11. Bush K, Jacoby GA, Medeiros AA (1995) A functional classification scheme for b-lactamases and its correlation with molecular structure. Antimicrob Agents Chemother 39:1211-33.
12. Lee K, Chong Y, Shin HB, Kim YA, Yong D, Yum JH (2001) Modified Hodge and EDTA-disk synergy tests to screen Metallo-β-lactamase-producing strains of Pseudomonas and Acinetobacter species. Clin Microbiol Infect 7:88-91.
13. Lee K, Lim YS, Yong D, Yum JH, Chong Y (2003) Evaluation of the Hodge test and the imipenem-EDTA double-disk synergy test for differentiating Metallo-beta-lactamase producing isolates of Pseudomonas spp. and Acinetobacter spp. J Clin Microbiol 41:4623-29.
14. Yan JJ, Wu JJ, Tsai SH, Chuang CL (2004) Comparison of the double-disk, combined disk, and Etest methods for detecting Metallo-β-lactamases in Gram-negative bacilli. Diagn Microbiol Infect Dis 49:5-11.
15. Arakawa Y, Shibata N, Shibayama K, Kurokawa H, Yagi T, Fujiwara H, Goto M (2000) Convenient test for screening metallo-β-lactamase-producing Gram-negative bacteria by using thiol compounds. J Clin Microbiol 38:40-43.
16. Yong D, Lee K, Yum JH, Shin HB, Rossolini GM, Chong Y (2002) Imipenem-EDTA disk method for differentiation of Metallo-β-lactamase producing clinical isolates of Pseudomonas spp. and Acinetobacter spp. J Clin Microbiol 40:3798-801.
17. Walsh TR, Bolmstrom A, Qwarnstrom A, Gales A (2002) Evaluation of a new E-test for detecting metallo-β-lactamases in routine clinical testing. J Clin Microbiol 40:2755-59.
18. Migliavacca R, Docquier JD, Mugnaioli C, Amicosante G, Daturi R, Lee K (2002) Simple microdilution test for detection of metallo-β-lactamase production in Pseudomonas aeruginosa. J Clin Microbiol 40:4388-90.
19. Richet HM, Mohammed J, McDonald LC, Jarvis WR (2001) Building communication networks: international network for the study and prevention of emerging antimicrobial resistance. Emerg Infect Dis 7:319-22.
20. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing-19th informational supplement. (2009) Wayne, PA M100-S19. NCCLS.
21. Nordmann P and Poirel L (2002) Emerging carbapenemases in Gram negative aerobes. Clin Microbiol Infect 8:32131.
22. Senda K, Arakawa Y, Nakashima K, Ito H, Ichiyama S, Shimokata K, Kato N, Ohta M (1996) Multifocal outbreaks of metallo-β-lactamase producing Pseudomonas aeruginosa resistant to broad-spectrum β-lactams, including carbapenems. Antimicrob Agents Chemother 40:349-53.
23. Hemalatha V, Uma S, Vijay LK (2005) Detection of metallo betalactamase producing Pseudomonas aeruginosa in hospitalized patients. Indian J Med Res. 122:148-52.
24. Varsha G (2007) An update on newer beta lactamases. Indian J Med Res 26:41727.
25. Irfan S, Zafar A, Gauhar D, Hasan R (2006) Metallo beta lactamase producing clinical isolates of Acinetobacter species and Pseudomonas aeruginosa from intensive care unit of tertiary care hospital. Indian J Microbiol 26:243-45.